+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Pulmonary complications of hyponatremic encephalopathy. Noncardiogenic pulmonary edema and hypercapnic respiratory failure



Pulmonary complications of hyponatremic encephalopathy. Noncardiogenic pulmonary edema and hypercapnic respiratory failure



Chest 107(2): 517-521



Objective: To determine the causes of hypoxia in patients with hyponatremic encephalopathy. Design: Retrospective cohort study. Setting: Consultation and referral service of two university medical centers and community hospitals. Patients: Forty adults with postoperative hyponatremic encephalopathy and hypoxia of whom 30 had noncardiogenic pulmonary edema and 10 had hypercapnic respiratory failure. Main measurements: We evaluated the chest radiographs and measured plasma electrolytes, arterial blood gas values, pulmonary artery pressure, pulmonary capillary wedge pressure (PCWP), cardiac output, and net fluid retention. Results: Forty patients with hyponatremic encephalopathy had hypoxia (arterial PO-2 below 70 mm Hg), of whom 30 had pulmonary edema and 10 had hypercapnia (PCO-2 above 50 mm Hg). Among the 30 patients with pulmonary edema, the serum sodium (+- SD) was 114 +- 7 mmol/L, arterial pH was 7.24 +- 0.16, PCO-2 was 45 +- 15 mm Hg, and PO-2 was 42 +- 16 mm Hg. The cardiac index was 3.6 +- 0.4 L/min/M-2, pulmonary artery pressure was 26/16 mm Hg, and PCWP was 12 +- 6 mm Hg. There was pulmonary edema, with normal heart size. The hypoxic patients who did not have pulmonary edema had significant hypercapnia (PCO-2=91 +- 29 mm Hg, p lt 0.001). Conclusions: Patients with postoperative hyponatremic encephalopathy can develop hypoxia by at least two different mechanisms: noncardiogenic pulmonary edema or hypercapnic respiratory failure.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 009273965

Download citation: RISBibTeXText

PMID: 7842787


Related references

Noncardiogenic pulmonary edema with hypoxemia in patients with hyponatremic encephalopathy. Clinical Research 42(2): 295A, 1994

Hyponatremic encephalopathy presenting as noncardiogenic pulmonary edema in marathon runners. Journal of the American Society of Nephrology 10(PROGRAM AND ABSTR ISSUE): 119A, 1999

Noncardiogenic pulmonary edema with hypoxia as the inital manifestation of hyponatremic encephalopathy. Journal of the American Society of Nephrology 4(3): 292, 1993

Diagnostic and prognostic utility of brain natriuretic Peptide in subjects admitted to the ICU with hypoxic respiratory failure due to noncardiogenic and cardiogenic pulmonary edema. Chest 131(4): 964-971, 2007

Hyponatremic encephalopathy with non-cardiogenic pulmonary edema. Development following marathon run. Medizinische Klinik Intensivmedizin und Notfallmedizin 108(3): 234-237, 2013

Pulmonary Complications of Hyponatremic Encephalopathy. Chest Journal 107(2): 517-521, 1995

Pulmonary edema and acute hypercapnic respiratory failure treated with bi-level nasal-CPAP: case report. Panminerva Medica 39(1): 53-55, 1997

Oxygen radical induced pulmonary edema a mechanism for the production of noncardiogenic pulmonary edema by neutrophils. Chest 81(5 Suppl.): 57S-59S, 1982

Noncardiogenic pulmonary edema and venous air embolus as complications of operative hysteroscopy. Journal of Clinical Anesthesia 16(1): 48-50, 2004

The spectrum of pulmonary edema: differentiation of cardiogenic, intermediate, and noncardiogenic forms of pulmonary edema. American Review of Respiratory Disease 124(6): 718-722, 1981

Do patients with cardiogenic pulmonary edema develop noncardiogenic pulmonary edema. American Review of Respiratory Disease 139(4 Part 2): A271, 1989

Noncardiogenic pulmonary edema and acute kidney failure after withdrawal of a central venous catheter. Revista Espanola de Anestesiologia Y Reanimacion 51(7): 399-402, 2004

Monitoring mechanics of the respiratory system and lung in experimentally induced noncardiogenic and cardiogenic pulmonary edema. American Review of Respiratory Disease 115(4 Part 2): 323, 1977

Microangiopathic hemolytic anemia, renal failure, and noncardiogenic pulmonary edema: a chemotherapy-induced syndrome. Cancer Treatment Reports 67(5): 429-434, 1983

Pulmonary hypertension and noncardiogenic pulmonary edema following cardiopulmonary bypass associated with an antigranulocyte antibody. Anesthesiology 64(1): 106-111, 1986