EurekaMag
+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Tabanidae
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Purification and characterization of an interleukin-1beta-converting enzyme family protease that activates cysteine protease P32 (CPP32)


Purification and characterization of an interleukin-1beta-converting enzyme family protease that activates cysteine protease P32 (CPP32)



Journal of Biological Chemistry 271(23): 13371-13376



ISSN/ISBN: 0021-9258

PMID: 8662833

CPP32, a member of the interleukin-1-beta-converting enzyme (ICE) family of cysteine proteases, cleaves poly(ADP-ribose) polymerase and sterol regulatory element binding proteins during apoptosis. CPP32 normally exists in the cytosol as a 32-kDa inactive precursor and only becomes activated when cells are undergoing apoptosis. The activation is a proteolytic event that generates a p20/p11 heterodimer.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 009276986

Download citation: RISBibTeXText

Related references

Purification and characterization of an interleukin-1b-converting enzyme family protease that activates cysteine protease P32. The Journal of Biological Chemistry 271: 371-6, 1996

Molecular characterization of mouse and rat CPP32 beta gene encoding a cysteine protease resembling interleukin-1 beta converting enzyme and CED-3. Oncogene 13(4): 749-755, 1996

Purification of an interleukin-1 beta converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains. Journal of Biological Chemistry 270(30): 18044-18050, 1995

Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer. Cell 78(2): 343-352, 1994

Identification of a cysteine protease closely related to interleukin-1 beta-converting enzyme. European Journal of Biochemistry 236(1): 207-213, 1996

Identification and mapping of Casp7, a cysteine protease resembling CPP32 beta, interleukin-1 beta converting enzyme, and CED-3. Genomics 40(1): 86-93, 1997

Interleukin-1 beta converting enzyme: a novel cysteine protease required for IL-1 beta production and implicated in programmed cell death. Protein Science: a Publication of the Protein Society 4(1): 3-12, 1995

Purification of interleukin-1 beta converting enzyme, the protease that cleaves the interleukin-1 beta precursor. Archives of Biochemistry and Biophysics 296(2): 698-703, 1992

Inhibitors of cysteine protease interleukin-1-beta-converting enzyme abolish the apoptosis of ST-1 cells induced by nephrotoxicant pesticides. Journal of the American Society of Nephrology 7(9): 1843, 1996

Purification of an interleukin-1b converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains. The Journal of Biological Chemistry 270: 044-50, 1995

Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis. Biochemical Journal 319: 683-690, 1996

Phosphatidylserine externalization is a downstream event of interleukin-1 beta-converting enzyme family protease activation during apoptosis. Blood 89(6): 2060-2066, 1997

Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli. Journal of Experimental Medicine 184(6): 2445-2450, 1996

Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases. Journal of Biological Chemistry 270(25): 15250-15256, 1995

Identification of a cysteine protease closely related to interleukin-1b-converting enzyme. European Journal of Biochemistry 236: 7-13, 1996