Retardation by the soybean Bowman-Birk inhibitor of elastin hydrolysis catalyzed by leukocyte proteinases

Tikhonova, T.V.; Gladysheva, I.P.; Larionova, N.I.

FEBS Letters 362(2): 225-228

1995


ISSN/ISBN: 0014-5793
PMID: 7720877
DOI: 10.1016/0014-5793(95)00202-k
Accession: 009352368

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Abstract
The classical Bowman-Birk inhibitor from soya retards strongly the hydrolysis of elastin catalyzed by leukocyte elastase, cathepsin G and a mixture of both. The inhibitory effect is practically unaffected by both the adsorption of the enzymes on elastin and prolongation of the enzymatic reaction.