Section 10
Chapter 9,393

Selective inhibitors of monoamine oxidase (MAO) . 5. 1-Substituted phenoxathiin inhibitors containing no nitrogen that inhibit MAO A by binding it to a hydrophobic site

Harfenist, M.; McGee, D.P.; Reeves, M.D.; White, H.L.

Journal of Medicinal Chemistry 41(12): 2118-2125


ISSN/ISBN: 0022-2623
PMID: 9622553
DOI: 10.1021/jm970862j
Accession: 009392551

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It is believed that a monoamine oxidase (MAO) inhibitor specific for MAO A, which is reversibly bound to this enzyme and displaceable by tyramine, will be an antidepressant which will not cause a rise in blood pressure when tyramine-containing foods are ingested.

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