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Sensing the heat: The application of isothermal titration calorimetry to thermodynamic studies of biomolecular interactions

Sensing the heat: The application of isothermal titration calorimetry to thermodynamic studies of biomolecular interactions

Chemistry and Biology (London) 3(10): 791-801

Biomolecular interactions can be defined by combining thermodynamic data on the energetic properties of the interaction with high-resolution structural data. The development of high sensitivity isothermal titration calorimetric equipment provides a dramatic advance in the gathering of thermodynamic data, and the interactions between biological macromolecules can now be described with unprecedented accuracy.

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Accession: 009395620

Download citation: RISBibTeXText

PMID: 8939696

DOI: 10.1016/s1074-5521(96)90063-0

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