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Serum antibody production by oral immunization with dextran B512

Serum antibody production by oral immunization with dextran B512

Journal of Immunological Methods 159(1-2): 245-251

Serum antibodies to dextran were detected when dextran B512 was orally administered to C3H/He mice. The amounts of serum antibodies were increased along with the dose of orally administered dextran B512. For serum antibody production, differences were observed among the strains of mice. C3H/He, C57BL/6 and CBA mice produced high levels of serum antibodies to dextran, while BALB/c and DBA/2 mice produced low levels of serum antibodies. The serum antibodies had groove-type combining sites, as determined by ELISA inhibitory assay.

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Accession: 009404616

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PMID: 7680367

DOI: 10.1016/0022-1759(93)90163-2

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