Section 10
Chapter 9,405

Serum antibody response in calves receiving modified live and/or inactivated vaccines containing bovine herpesvirus-1, bovine viral diarrhea virus, parainfluenza-3 virus, and bovine respiratory syncytial virus immunogens

Fulton, R.W.; Burge, L.J.; D'offay, J.M.; Payton, M.E.

Bovine Practitioner 1997(31 Part 2): 90-96


ISSN/ISBN: 0524-1685
Accession: 009404623

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Serum antibody responses to bovine herpesvirus-1(BHV-1), bovine viral diarrhea virus (BVDV), parainfluenza-3 virus (PI-3V), and bovine respiratory syncytial virus (BRSV) by calves receiving viral vaccines were evaluated. Calves were vaccinated at day 0 with one of four commercial vaccines containing BHV-1, BVDV, PI-3V, and BRSV immunogens. Selected vaccines were given a second time at day 28. Calves were revaccinated at day 140 with the respective vaccine given at day 0. The vaccines contained modified live virus (MLV) and/or inactivated components. Serums were collected at day 0 and at various intervals through day 196, and assayed for viral neutralizing antibodies. Between various vaccine groups there were differences in onset and duration of serum antibodies to each immunogen postvaccination. Anamnestic responses after day 140 revaccination to some but not all viruses were sometimes dependent on the type vaccine and level of antibodies at revaccination.

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