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Sleep quality and nocturnal respiratory function with once-daily theophylline (Uniphyl) and inhaled salbutamol in patients with COPD

Sleep quality and nocturnal respiratory function with once-daily theophylline (Uniphyl) and inhaled salbutamol in patients with COPD

Chest 110(3): 648-653

We compared the effects of evening administration of sustained-release theophylline (Uniphyl) and qid inhaled beta-2-agonist (salbutamol, two 100-mu-g puffs) on sleep quality and nocturnal oxygen saturation in 20 patients with COPD. Patients with FEV-1 less than 70% predicted and FEV-1/FVC ratio less than 70% were eligible to participate in this double-blind, crossover study, with 2-week treatment arms. Patients recorded morning and evening peak flow and symptoms in a daily diary.

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Accession: 009425433

Download citation: RISBibTeXText

PMID: 8797406

DOI: 10.1378/chest.110.3.648

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