EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Stable and temperature-sensitive transformation of rat kidney epithelial cells suppresses expression of acidic fibroblast growth factor 1 but activates secretion of fibroblast growth factor 3 (int-2) and vascular endothelial growth factor



Stable and temperature-sensitive transformation of rat kidney epithelial cells suppresses expression of acidic fibroblast growth factor 1 but activates secretion of fibroblast growth factor 3 (int-2) and vascular endothelial growth factor



Cell Growth & Differentiation 5(4): 349-357



Rat kidney proximal tubule epithelial cells (RPTE) in primary culture express acidic fibroblast growth factor 1 (FGF-1). Transformation of RPTE by SV40 (SV-RPTE) suppressed FGF-1 expression but activated secretion of FGF-like factor(s). SV-RPTE conditioned medium contained growth-promoting activity for SV-RPTE and human umbilical vein endothelial cells, indicating that both autocrine and angiogenic factors were secreted.

(PDF emailed within 1 workday: $29.90)

Accession: 009451552

Download citation: RISBibTeXText

PMID: 7519042



Related references

Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Research 57(5): 963-969, 1997

Expression of transforming growth factor alpha/epidermal growth factor receptor, hepatocyte growth factor/c-met and acidic fibroblast growth factor/fibroblast growth factor receptors during hepatocarcinogenesis. Carcinogenesis 17(5): 931-938, 1996

Expression of transforming growth factor-alpha/epidermal growth factor receptor, hepatocyte growth factor/c-met, acidic fibroblast growth factor/fibroblast growth factor receptors during hepatocarcinogenesis. Hepatology 18(4 PART 2): 160A, 1993

Immunohistochemical localization of growth factors fibroblast growth factor-1 and fibroblast growth factor-2 and receptors fibroblast growth factor receptor-2 and fibroblast growth factor receptor-3 in normal oral epithelium, epithelial dysplasias, and squamous cell carcinoma. Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics 93(5): 573-579, 2002

Increased expression of transforming growth factor-beta1, acidic fibroblast growth factor, and basic fibroblast growth factor in fetal versus adult fibroblast cell lines. Laryngoscope 110(4): 616-619, 2000

Basic fibroblast growth factor and epithelial growth factor induces production of vascular endothelial growth factor and soluble receptor by human aortic smooth muscle cells. European Heart Journal 22(Abstract Supplement): 485, September, 2001

Priming Dental Pulp Stem Cells With Fibroblast Growth Factor-2 Increases Angiogenesis of Implanted Tissue-Engineered Constructs Through Hepatocyte Growth Factor and Vascular Endothelial Growth Factor Secretion. Stem Cells Translational Medicine 5(3): 392-404, 2016

Growth factor regulation of the renal cortical tubular cells by epidermal growth factor, insulin-like growth factor-I, acidic and basic fibroblast growth factor, and transforming growth factor-beta in serum free culture. Cell Biology International Reports 13(8): 687-699, 1989

Growth factor regulation of the renal cortical tubular cells by epidermal growth factor, insulin-like growth factor-I, acidic and basic fibroblast growth factor, and transforming growth factor-β in serum free culture. Cell Biology International Reports 13(8): 687-699, 1989

Zoledronic acid decreases gene expression of vascular endothelial growth factor and basic fibroblast growth factor by human epithelial cells. British Journal of Oral & Maxillofacial Surgery 51(8): 971-973, 2015

Localization of acidic fibroblast growth factor, fibroblast growth factor receptor-4, transforming growth factor-alpha, and epidermal growth factor receptor in human endocrine cells of the gut and related tumors: An immunohistochemical study. Applied Immunohistochemistry 6(4): 199-208, 1998

Regulation of sonic hedgehog on vascular endothelial growth factor, basic fibroblast growth factor expression and secretion in bone marrow mesenchymal stem cells. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 26(1): 112-116, 2012

Differential action of vascular endothelial growth factor and basic fibroblast growth factor , the two major angiogenic growth factors, on secretion of C-type natriuretic peptide from endothelial cells. Circulation 92(8 SUPPL ): I695, 1995

Vascular endothelial growth factor, hepatocyte growth factor/scatter factor, basic fibroblast growth factor, and placenta growth factor in human meningiomas and their relation to angiogenesis and malignancy. Neurosurgery 46(4): 938-47; Discussion 947-8, 2000

Vascular endothelial growth factor, basic fibroblast growth factor and epithelial growth factor receptor in peripheral nerve sheath tumors of neurofibromatosis type 1. Anticancer Research 35(1): 137-144, 2015