Structural elucidation of the capsular polysaccharide of Bacteroides fragilis strain 23745M1

Pavliak, V.; Uhrín, D.; Brisson, J.R.; Tzianabos, A.O.; Kasper, D.L.; Jennings, H.J.

Carbohydrate Research 275(2): 333-341


ISSN/ISBN: 0008-6215
PMID: 8529227
DOI: 10.1016/0008-6215(95)00158-p
Accession: 009465666

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The capsule of Bacteroides fragilis (ATCC23745) consists of two distinct polysaccharides, the separation of which could not be accomplished. The mouse-passaged strain (23745M1), however, yielded a preponderant polysaccharide which was isolated and purified. Using mainly high resolution NMR spectroscopy, the structure of the polysaccharide was elucidated and it is composed of the following repeating unit: