Study of auto-rosette formation in circulating blood

Belchenko, D.I.

Klinicheskaia Laboratornaia Diagnostika 1993(3): 58-62


ISSN/ISBN: 0869-2084
PMID: 8963542
Accession: 009478617

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Examination of blood smears of humans and laboratory animals has shown endogenic intravascular auto-rosette formation by monocytes and granulocytes. The intensity of this phenomenon significantly increased in case of hereditary hemolytic anemias in children and in acute respiratory diseases of adults, in posthemorrhagic and hemolytic anemias of rabbits, and rats with hypokinesia, that is, in states associated with the appearance in the circulating blood of red cells with changed membrane characteristics. Intensified auto-rosette formation in the circulating blood may be an indicator of the immune system activity and the body adaptation to changed life conditions.