Synthesis and evaluation of C-Seco paclitaxel analogues

Appendino, G.; Danieli, B.; Jakupovic, J.; Belloro, E.; Scambia, G.; Bombardelli, E.

Tetrahedron Letters 38(24): 4273-4276

1997


ISSN/ISBN: 0040-4039
DOI: 10.1016/s0040-4039(97)00877-0
Accession: 009505146

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Abstract
Starting from 7,9-diTes-10-dehydro C-secobaccatin III (4a), C-seco analogues of paclitaxel retaining biological activity were synthesised.