Synthesis of CD-ring modified 1-alpha,25-dihydroxy vitamin D analogues: E-ring analogues

Sabbe, K.; D'hallewyn, C.; De-Clercq, P.; Vandewalle, M.; Bouillon, R.; Verstuyf, A.

Bioorganic and Medicinal Chemistry Letters 6(14): 1697-1702

1996


ISSN/ISBN: 0960-894X
Accession: 009507471

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Abstract
Vitamin D analogues, characterized by the absence of both C- and D-rings and by the presence of a five-membered ring formed by connecting C-12 and C-21 (E-ring analogues) are described.