Home
  >  
Section 10
  >  
Chapter 9,508

Synthesis of CMP-deaminoneuraminic acid (CMP-KDN) using the CTP:CMP-3-deoxynonulosonate cytidylyltransferase from rainbow trout testis. Identification and characterization of a CMP-KDN synthetase

Terada, T.; Kitazume, S.; Kitajima, K.; Inoue, S.; Ito, F.; Troy, F.A.; Inoue, Y.

Journal of Biological Chemistry 268(4): 2640-2648

1993

ISSN/ISBN: 0021-9258
PMID: 8381411
Accession: 009507473
The sugar nucleotide, cytidine 5'-(3-deoxy-D-glycero-D-galacto-2-nonulosonic phosphate) (CMP-KDN) is expected to serve as a donor of KDN residues in the synthesis of KDN-containing glycoconjugates. We report here the identification and characterization of CMP-KDN synthetase, a novel enzyme responsible for synthesis of CMP-KDN from KDN and CTP.

PDF emailed within 1 workday: $29.90




Related References

Terada, T.; Kitazume, S.; Kitajima, K.; Inoue, S.; Ito, F.; Troy, F.A.; Inoue, Y. 1993: CMP-3-deoxynonulosonate synthetase which catalyzes the transfer of CMP to KDN from CTP Partial purification and characterization of the enzyme from rainbow trout testis Roth, J , Rutishauser, U , Troy, F A , II Advances in Life Sciences; Polysialic acid: From microbes to man : 191-199
Wu, D.; Gilormini, P.-A.é; Toda, S.; Biot, C.; Lion, C.éd.; Guérardel, Y.; Sato, C.; Kitajima, K. 2022: A novel C-domain-dependent inhibition of the rainbow trout CMP-sialic acid synthetase activity by CMP-deaminoneuraminic acid Biochemical and Biophysical Research Communications 617(Part 1): 16-21
Terada, T.; Kitajima, K.; Inoue, S.; Koppert, K.; Brossmer, R.; Inoue, Y. 1996: Substrate specificity of rainbow trout testis CMP-3-deoxy-D-glycero-D-galacto-nonulosonic acid (CMP-Kdn) synthetase: kinetic studies of the reaction of natural and synthetic analogues of nonulosonic acid catalyzed by CMP-Kdn synthetase European Journal of Biochemistry 236(3): 852-855
Terada, T.; Song, Y.; Angata, T.; Kitazume, S.; Kitajima, K.; Inoue, S.; Troy, F.A.; Inoue, Y. 1993: S18.16 Enzymatic synthesis of neoglycoconjugates containing Kdn residues: use of Cmp-Kdn synthetase and Kcn-transferase from rainbow trout testis for synthesis of Kdn-glycoproteins and Kdn-glycosphingolipids Glycoconjugate Journal 10(4): 331-332
Angata, T.; Nakata, D.; Matsuda, T.; Kitajima, K.; Troy, F.A. 1999: Biosynthesis of KDN (2-keto-3-deoxy-D-glycero-D-galacto-nononic acid). Identification and characterization of a KDN-9-phosphate synthetase activity from trout testis Journal of Biological Chemistry 274(33): 22949-22956
Song, Y.; Kitajima, K.; Inoue, S.; Khoo, K.H.; Morris, H.R.; Dell, A.; Inoue, Y. 1995: Expression of new KDN-gangliosides in rainbow trout testis during spermatogenesis and their structural identification Glycobiology 5(2): 207-218
Gedamu, L.; Dixon, G.H.; Davies, P.L. 1977: Identification and isolation of protamine messenger ribonucleoprotein particles from rainbow trout testis Biochemistry 16(7): 1383-1391
Jergil, B.; Dixon, G.H. 1970: Protamine kinase from rainbow trout testis. Partial purification and characterization Journal of Biological Chemistry 245(2): 425-434
Nakata, D.; Münster, A.K.; Gerardy-Schahn, R.; Aoki, N.; Matsuda, T.; Kitajima, K. 2001: Molecular cloning of a unique CMP-sialic acid synthetase that effectively utilizes both deaminoneuraminic acid (KDN) and N-acetylneuraminic acid (Neu5Ac) as substrates Glycobiology 11(8): 685-692
Jergil, B. 1972: Protein kinase from rainbow-trout-testis ribosomes. Partial purification and characterization European Journal of Biochemistry 28(4): 546-554
Schalburg, K.R.; Yasuike, M.; Davidson, W.S.; Koop, B.F. 2010: Regulation, expression and characterization of aromatase transcripts in ovary and testis of rainbow trout Comparative Biochemistry And Physiologyochemistry and Molecular Biology: 2, 118-125
Farlora, R.; Valenzuela-Miranda, D.; Alarcón-Matus, P.; Gallardo-Escárate, C. 2015: Identification of micro RNAs associated with sexual maturity in rainbow trout brain and testis through small RNA deep sequencing Molecular Reproduction and Development 82(9): 651-662
Pérez-Sánchez, T.; Balcázar, J.L.; García, Y.; Halaihel, N.; Vendrell, D.; de Blas, I.; Merrifield, D.L.; Ruiz-Zarzuela, I. 2011: Identification and characterization of lactic acid bacteria isolated from rainbow trout, Oncorhynchus mykiss (Walbaum), with inhibitory activity against Lactococcus garvieae Journal of Fish Diseases 34(7): 499-507
Gillam, S.; Aline, R.; Wylie, V.; Ingles, C.J.; Smith, M. 1979: RNA synthesis and RNA polymerase activities in germ cells of developing rainbow trout testis Biochimica et Biophysica Acta 565(2): 275-292
Jin, Z.X.; Morisawa, M.; Hayashi Sugashima, H. 1992: Characterization and partial purification of a protein kinase-substrate complex from the testis of rainbow trout Cell Motility and the Cytoskeleton 23(4): 304