+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Tests of sperm function for evaluation of the male: Penetrak and Tru-Trax



Tests of sperm function for evaluation of the male: Penetrak and Tru-Trax



Fertility and Sterility 60(2): 319-323



Objective: To evaluate the Penetrak (Serono Laboratories, Norwell, MA) and Tru-Trax (Humagen, Charlottesville, VA) bovine cervical mucus (CM) penetration assays and to correlate results to parameters of semen analysis and male factor diagnosis. Design: Prospective, nonrandomized, controlled study. Participants. Two hundred thirty-six males undergoing evaluation for male factor infertility and 37 fertile semen donors. Main Outcome Measures: Human sperm penetration in bovine CM measured by the Penetrak and Tru-Trax assay systems correlated to sperm density, motility, forward progression, and clinical diagnosis. Results: Two parameters of semen analysis, motility and density were correlated to the distance traversed by the vanguard sperm in both Penetrak and Tru-Trax assays. Penetrak results were significantly correlated to male factor infertility diagnosis. Conclusions: Both assays were reliable and highly reproducible, and the Tru-Trax assay was correlated to its predecessor, Penetrak. Although Penetrak and Tru-Trax were correlated to motility and density, no correlation coefficient was gt 0.6, suggesting that these assays measure a facet of sperm function that is independent of semen analysis.

(PDF emailed within 1 workday: $29.90)

Accession: 009526636

Download citation: RISBibTeXText

PMID: 8339831


Related references

Tests of sperm function for the evaluation of the male penetrak and tru trax. Journal of Urology 147(4 SUPPL): 323A, 1992

Prognostic value of two putative sperm function tests: hypo-osmotic swelling and bovine sperm mucus penetration test (Penetrak). Human Reproduction 7(9): 1240-1244, 1992

Evaluation of human sperm function with bovine cervical mucus penetrak. Japanese Journal of Fertility & Sterility 34(1): 126-133, 1989

Evaluation of different sperm function tests as screening methods for male fertilization potential--the value of the sperm migration test. Fertility and Sterility 62(3): 591-598, 1994

Fertility and Sperm Function in Cryptorchidism after Orchiopexy-Evaluation with Penetrak Test and Hypoosmotic Swelling Test. Japanese Journal of Fertility & Sterility 39(3): 299-304, 1994

The variance of repeated penetrak value for the estimation of sperm motility function. Japanese Journal of Fertility & Sterility 36(2): 69-71, 1991

Effects of microsurgical varicocelectomy on semen analysis and sperm function tests in patients with different grades of varicocele: Role of sperm functional tests in evaluation of treatments outcome. Andrologia: E13069-E13069, 2018

Evaluation of the effects of Hotyu-ekki-to on human sperm motility as assessed by the Penetrak test, hypoosmotic swelling test and computer-assisted semen analyzer. Japanese Journal of Fertility & Sterility 38(4): 654-660, 1993

Detective and predictive values for the sperm function laboratory tests in male infertility. Clinical Chemistry & Laboratory Medicine 37(SPEC SUPPL ): S102, June, 1999

Use of penetrak to study sperm penetration patterns. Journal of Andrology 8(1): P-28, 1987

The relationship between human sperm motility and penetrak test. Japanese Journal of Fertility & Sterility 35(1): 74-79, 1990

The Sperm Chromatin Structure Assay (SCSA(®)) and other sperm DNA fragmentation tests for evaluation of sperm nuclear DNA integrity as related to fertility. Animal Reproduction Science 169: 56-75, 2016

Male infertility: evaluation of human sperm function and its clinical application. Journal of Endocrinological Investigation 18(6): 468-483, 1995

An evaluation of semen analysis and in-vitro tests of sperm function in the prediction of the outcome of intrauterine AIH. Human Reproduction 4(6): 674-679, 1989

Tamoxifen treatment of oligozoospermia: A re-evaluation of its effects including additional sperm function tests. Archives of Gynecology & Obstetrics 252(3): 143-147, 1993