+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The long term prognosis of infective endocarditis



The long term prognosis of infective endocarditis



European Heart Journal 16 Suppl B: 48-53



Three problems hamper the prognosis of patients who survive the initial phase of infective endocarditis (IE): the rate of IE recurrence is 0.3-2.5/100 patient years, about 60% of patients will have to be operated on at some time, 20-30% during the initial stay, 30-40% during the following 5-8 years; five-year survival after the hospital phase is about 75% in previous reports and 85% in more recent papers. Death is mainly due to heart failure. We looked at the long-term survival of 330 patients with IE who were hospitalized in our institution in 1970-1982, and at the potential influence of 10 factors: age, gender, previous heart disease, microorganism, location of IE, onset of IE, congestive heart failure (CHF) at onset, CHF during the first year, persistent fever, surgery at the acute phase. Global survival was 75% at 6 months, and 57% at 5 years. The only non-significant factor was IE location. The annual instantaneous risk of death was 0.55 at 6 months, 0.18 at 1 year, then 0.03. After one year, the only prognostic factor was age. The relative risk of dying among patients with IE who survived the first year, as compared to the risk of dying among the general population, was 3.27. The IE prognosis is not uniform. Mortality is high during the initial phase, but after one year the risk of dying is low, although still above that of the general population. Part of the risk is probably the direct consequence of IE, but part is due to the course of the underlying heart disease.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 009596242

Download citation: RISBibTeXText

PMID: 7671924

DOI: 10.1093/eurheartj/16.suppl_b.48


Related references

Short and long-term prognosis of infective endocarditis. Israel Journal of Medical Sciences 32(10): 905, 1996

Multivariant analysis of the short- and very long-term prognosis of infective endocarditis. European Heart Journal 15(ABSTR Suppl. ): 216, 1994

Long-term prognosis of infective endocarditis Are embolic phenomena associated with a higher mortality?. European Heart Journal 23(Abstract Suppl.): 479, August-September, 2002

Long-term prognosis of infective endocarditis with an initial good outcome Have we definitively solved the problem?. European Heart Journal 24(Abstract Suppl.): 470, August-September, 2003

A nationwide cohort study of mortality risk and long-term prognosis in infective endocarditis in Sweden. Plos one 8(7): E67519, 2013

Impact of echocardiography in the short- and long-term prognosis of patients with infective endocarditis and negative blood cultures. Journal of Heart Valve Disease 13(6): 997, 2004

Short- and long-term prognosis of infective endocarditis in non-injection drug users: improved results over 15 years (1987-2001). Revista Espanola de Cardiologia 58(10): 1188-1196, 2005

Time interval between infective endocarditis first symptoms and diagnosis: relationship to infective endocarditis characteristics, microorganisms and prognosis. Annals of Medicine 49(2): 117-125, 2017

Prophylaxis of experimental endocarditis with antiplatelet and antithrombin agents: a role for long-term prevention of infective endocarditis in humans?. Journal of Infectious Diseases 211(1): 72-79, 2015

Infective endocarditis: mid-term prognosis in patients with good in-hospital outcome. Journal of Heart Valve Disease 14(3): 303-309, 2005

Short-term prognosis of infective endocarditis in a one-year French prospective cohort. European Heart Journal 23(Abstract Suppl.): 24, August-September, 2002

Incidence and short-term prognosis of infective endocarditis in Denmark, 1980-1997. Scandinavian Journal of Infectious Diseases 35(1): 27-30, 2003

Infective endocarditis: determinants of long term outcome. Heart 88(1): 61-66, 2002

Long-term survival of patients with infective endocarditis. Journal of Insurance Medicine 30(2): 76-87, 1998

Long-term results of surgery for active infective endocarditis. European Journal of Cardio-Thoracic Surgery 11(1): 46-52, 1997