EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

The significance of luteal support for in vitro fertilization and embryo transfer patients



The significance of luteal support for in vitro fertilization and embryo transfer patients



Japanese Journal of Fertility & Sterility 38(4): 629-634



To investigate the efficacy of luteal support in in vitro fertilization and embryo transfer (IVF-ET) patients using gonadotropin releasing hormone agonist (GnRH-a), serum progesterone (P), estradiol (E-2), luteinizing hormone (LH) and follicle stimulating hormone (FSH) were measured at several points in all cycles of IVF-ET cases of forty patients during 1991 in our department. Sixteen out of 29 cases who received P and human chorionic gonadotropin (hCG) supplement as luteal support became pregnant and 9 cases had on-going pregnancy, whereas, 11 patients who received only hCG resulted in unsuccessful. Low LH level lt 1.3 mIU/mL at the time of hCG injection was necessary to achieve pregnancy; in contrast, P level was not a good indicator for predicting IVF outcome. Both P and E-2 levels climbed up at day 10 after IVF in successful cases, whereas unsuccessful cases showed low P and E-2 not only in cases without P supplement but in P supplemented cycles as well. The addition of P to hCG administration may have a role for successful IVF-ET despite no significant increase of serum P levels.

(PDF emailed within 1 workday: $29.90)

Accession: 009625832

Download citation: RISBibTeXText



Related references

Estrogen role in the luteal phase support in in vitro fertilization with embryo transfer cycles. Ginecologia Y Obstetricia de Mexico 72(): 645-655, 2005

Salivary oestradiol and progesterone after in vitro fertilization and embryo transfer using different luteal support regimens. Reproduction, Fertility, and Development 2(4): 351-358, 1990

Efficacy of progesterone support in the luteal phase following in-vitro fertilization and embryo transfer: meta-analysis of clinical trials. Human Reproduction 3(6): 731-734, 1988

Luteal phase support for in vitro fertilization-embryo transfer--present and future methods to improve successful implantation. Clinical and Experimental Obstetrics & Gynecology 39(4): 422-428, 2013

Matched-samples comparison of intramuscular versus vaginal progesterone for luteal phase support after in vitro fertilization and embryo transfer. Fertility and Sterility 91(6): 2445-2450, 2008

Up to date experience with in vitro fertilization procedures pregnancies after a short protocol of leuprolide acetate human menopausal gonadotropin human chorionic gonadotropin without luteal phase support in an in vitro fertilization embryo transfer program. Negro-Vilar, A And G Perez-Palacios (Ed ) Serono Symposia Publications From Raven Press, Vol 71 Reproduction, Growth And Development; Meeting, Acapulco, Mexico, 1990 Xv+440p Raven Press: New York, New York, Usa Illus 347-357, 1991

Intramuscular versus vaginal administration of progesterone for luteal phase support after in vitro fertilization and embryo transfer. A comparative randomized study. Clinical and Experimental Obstetrics & Gynecology 26(3-4): 203-206, 2000

Chorionic gonadotropin support of the luteal phase following in vitro fertilization and embryo transfer. Randomized comparison with oral progesterone in protocols using triptoreline. Presse Medicale 18(10): 539-539, 1989

Luteal-phase support in stimulated cycles in an in vitro fertilization/embryo transfer program: progesterone versus human chorionic gonadotropin. Journal of in Vitro Fertilization and Embryo Transfer 5(2): 81-84, 1988

Granulosa luteal cell hcg responsiveness in vitro its interest for luteal supplementation in in vitro fertilization and embryo transfer. Contraception Fertilite Sexualite 18(7-8): 614-615, 1990

Mock embryo transfer in early luteal phase, the cycle before in vitro fertilization and embryo transfer: a descriptive study. Fertility and Sterility 57(1): 156-162, 1992

Crinone vaginal gel is equally effective and better tolerated than intramuscular progesterone for luteal phase support in in vitro fertilization-embryo transfer cycles: a prospective randomized study. Fertility and Sterility 94(7): 2596-2599, 2011

Vaginal micronized progesterone versus intramuscular progesterone for luteal support in women undergoing in vitro fertilization-embryo transfer. Fertility and Sterility 93(2): 554-569, 2010

Estradiol supplementation during the luteal phase may improve the pregnancy rate in patients undergoing in vitro fertilization-embryo transfer cycles. Fertility & Sterility 73(4): 761-766, April, 2000