+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The subaffective-character spectrum subtyping distinction in primary early-onset dysthymia: A clinical and family study

The subaffective-character spectrum subtyping distinction in primary early-onset dysthymia: A clinical and family study

Journal of Affective Disorders 38(1): 13-22

In 1983, Akiskal proposed that primary early-onset dysthymia should be divided into two subtypes: subaffective dysthymia, which is a subsyndromal form of major mood disorder; and character spectrum disorder, which is a form of personality disorder with secondary dysphoria. The present study attempted to validate this distinction. Akiskal's (1983) criteria were applied to a sample of 97 early-onset dysthymic outpatients, yielding groups of 41 subaffective and 56 character spectrum patients. Patients were evaluated using structured interviews for Axis I and II disorders, family history of psychopathology, and the early home environment, and a comprehensive battery of questionnaires. In addition, direct and family history interviews were conducted with their first-degree relatives. There was mixed support for Akiskal's typology. Consistent with the model, subaffectives exhibited higher rates of major depression, depressive symptoms, and a number of depressive personality and cognitive features. In addition, there was a higher rate of alcoholism among the relatives of character spectrum patients. However, contrary to Akiskal's model, the groups did not differ on gender, unstable personality disorders, family history of mood disorders, or the early home environment.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 009629465

Download citation: RISBibTeXText

PMID: 8735155

DOI: 10.1016/0165-0327(95)00088-7

Related references

Dexamethasone suppression test and TRH-TSH test in subaffective dysthymia and character-spectrum disorder. Journal Of Affective Disorders. 28(4): 287-291, 1993

Early- versus Late-Onset Dysthymia: A Meaningful Clinical Distinction?. Psychiatry: 14-17, 2009

The early--late onset distinction in DSM-III-R dysthymia. Journal of Affective Disorders 14(1): 25-33, 1988

Characterological depressions. Clinical and sleep EEG findings separating 'subaffective dysthymias' from 'character spectrum disorders'. Archives of General Psychiatry 37(7): 777-783, 1980

Understanding the comorbidity between early-onset dysthymia and cluster B personality disorders: a family study. American Journal of Psychiatry 153(7): 900-906, 1996

Primary early-onset dysthymia: comparison with primary nonbipolar nonchronic major depression on demographic, clinical, familial, personality, and socioenvironmental characteristics and short-term outcome. Journal of Abnormal Psychology 97(4): 387-398, 1988

Family study of early-onset dysthymia: Mood and personality disorders in relatives of outpatients with dysthymin and episodic major depression and normal controls. Archives of General Psychiatry 52(6): 487-496, 1995

Is late-onset dysthymia a different disorder than early-onset dysthymia?. Psiquis 25(2): 10-16, 2004

Subaffective disorders: dysthymia and cyclothymia. Mmw Fortschritte der Medizin 152(3): 31-33, 2010

Early-onset dysthymia and personality disturbance among patients in a primary care setting. Journal of Nervous and Mental Disease 186(1): 57-59, 1998

Biochemical measures related to therapeutic response to a specific serotonin reuptake inhibitor in early onset primary dysthymia. Society for Neuroscience Abstracts 18(1-2): 202, 1992