+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Transient acoustic cavitation in gallstone fragmentation: A study of gallstones fragmented in vivo

, : Transient acoustic cavitation in gallstone fragmentation: A study of gallstones fragmented in vivo. Ultrasound in Medicine & Biology 19(4): 331-342

The mechanism of gallstone fragmentation by shock waves in vivo is uncertain. We used scanning electron microscopy to study 9 partially fragmented stones obtained from 6 patients who underwent lithotripsy and subsequently had surgery because of incomplete fragmentation. Surface characteristics of the stone were studied using scanning electron microscopy and compared to gallstones fragmented in degassed water in vitro and to control stones obtained from patients with uncomplicated cholelithiasis. Characteristic damage caused by transient acoustic cavitation was visible in all stones fragmented in vivo and in vitro as pits 10-100 mu-m diameter. In these pits, cholesterol crystals were fractured, and the symmetry of crystal boundaries was damaged. In areas of more severe damage, individual pits coalesced to form craters on the stone surface. High magnification of the pit walls revealed cracks, which in some instances radiated out onto the unpitted surface of the stone. We conclude that transient acoustic cavitation plays a role in gallstone fragmentation in vivo through the mechanism of surface pitting and the formation of cracks that radiate outward from the surface pits. Measures to enhance cavitation may improve the results of gallstone lithotripsy.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 009665993

DOI: 10.1016/0301-5629(93)90105-W

Download PDF Full Text: Transient acoustic cavitation in gallstone fragmentation: A study of gallstones fragmented in vivo

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Stamm W.E.; Wagner K.F.; Tompkins L.S.; Thomas E.D.; Counts G.W.; Meyers J.D., 1978: Corynebacterium sepsis after marrow transplantation. Clinical Research 26(3): 407A

Beatty, G.L.; Haas, A.R.; Maus, M.V.; Torigian, D.A.; Soulen, M.C.; Plesa, G.; Chew, A.; Zhao, Y.; Levine, B.L.; Albelda, S.M.; Kalos, M.; June, C.H., 2015: Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies. Off-target toxicity due to the expression of target antigens in normal tissue represents a major obstacle to the use of chimeric antigen receptor (CAR)-engineered T cells for treatment of solid malignancies. To circumvent this issue, we establishe...

Muramatsu, R.; Misawa, S.; Hayashi, H., 2003: Finding of an isoleucine derivative of a recombinant protein for pharmaceutical use. Protein modification generally occurs by addition to the amino acid side-chains of protein at the post-translational stage, for example, by enzymatic or chemical reactions after polypeptide synthesis. Recently, the recombinant hirudin analog CX-39...

Hayashi, S., 1983: Wounds and the healing process: traumatic wounds and operative wounds. Nursing Technique 29(13): 1701-1706

Luchtefeld, M.A.; Senagore, A.J.; Szomstein, M.; Fedeson, B.; Van Erp, J.; Rupp, S., 2000: Evaluation of transarterial embolization for lower gastrointestinal bleeding. Transcatheter arterial embolization has been used as a therapeutic maneuver for lower gastrointestinal bleeding. The availability of highly selective arteriography has made this procedure safer and warrants re-evaluation. A retrospective chart rev...

V.I.K.ilis-Borok; L.K.opoff; V.K.ssobokov; I.R.tvain, 1990: Intermediate-term prediction in advance of the Loma Prieta earthquake. Geophysical Research Letters 17(9): 1461

Lim, S.; Han, J.; Kim, G.Min.; Han, K-Hyub.; Choi, H.Jin., 2016: Hepatitis B viral load predicts survival in hepatocellular carcinoma patients treated with sorafenib. Sorafenib is now considered as a standard treatment for advanced hepatocellular carcinoma (HCC). We evaluated the effect of hepatitis B virus (HBV) DNA titers on prognosis in HCC patients treated with sorafenib. From 2008 to 2012, 78 HBV-related H...

Floyd, R.A.; Hensley, K.; Bing, G., 2001: Evidence for enhanced neuro-inflammatory processes in neurodegenerative diseases and the action of nitrones as potential therapeutics. A brief review is presented on observations leading to the current notions regarding neuro-inflammatory processes. The greatest focus is on Alzheimer's disease (AD) since this is where the most convincing data has been obtained. A brief summa...

Witte, K.; Ryan, M.J., 1998: Male body length influences mate-choice copying in the sailfin molly Poecilia latipinna. Females can choose a male independently of other females' mate preferences, or they can copy the mate choice of other females. Alternatively, mate-choice copying and independent mate choice can interact if females assess male traits when deci...

Furet, Y.X.; Pechère, J.C., 1990: Usual and unusual antibacterial effects of quinolones. Recently documented antibacterial effects of quinolones are reviewed. DNA gyrase is most likely to be the primary target site for these agents. Quinolones rapidly kill susceptible bacteria; the mechanisms of the bactericidal activity, still poorly...