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Triazole-pyrazole compounds with possible biological activity: Part II

Triazole-pyrazole compounds with possible biological activity: Part II

Pakistan Journal of Scientific and Industrial Research 35(11): 428-433

Condensation of 4-formyl-2-aryl-1,2,3-triazoles with acetophenone derivatives afforded the chalcone (1) which react with different acyl- and arylhydrazines to give the corresponding hydrazones (2 and 3) or pyrazolines (4). Oxidation of (4) with bromine water yielded the pyrazole derivatives (5). Condensation of (4) and (5) with isothiocyanate gave the thioureas (6) and (7), which cyclized with ethyl bromoacetate to the corresponding thiazolidines (8) and (9).

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