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Use of 2,4-dinitrophenol for immunodepressive action on the recipient in fetal organ implantation in mice

Use of 2,4-dinitrophenol for immunodepressive action on the recipient in fetal organ implantation in mice

Byulleten' Eksperimental'noi Biologii i Meditsiny 113(4): 355-358

In experiments performed on 118 white mice and 10 laboratory rats, it was shown that cutaneous application of 2,4,-dinitrophenol microdoses once a week around the sites of fetal organ implantation leads to a significant prolongation of the implant life with minimal trouble for the recipient's health. The maximal effect was reached with 10-3 M concentration of DNP, the applictions beginning 2-3 weeks before fetal pancreas implantations.

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Accession: 009702296

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