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Use of MTT-method for determination of individual sensitivity of human ovarian tumors to cytostatic agents



Use of MTT-method for determination of individual sensitivity of human ovarian tumors to cytostatic agents



Eksperimental'naya Onkologiya 15(2): 72-77



An MTT-assay for determining individual sensitivity of ovarian tumor to anticancer treatment has been developed. The conditions providing for high sensitivity of the method were used. Individual sensitivity of the ACL-cell line and forty human malignant ovarian tumors to cytostatic agents was determined. The following significant merits to the MTT-assay have been found: its rapidness, cheapness, simplicity in execution, a possibility of simultaneous testing of several cancer samples, standardization of the analysis and conditions, strict quantitative estimation of the results, sufficiency of small amounts of the tumour material for testing.

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Accession: 009702595

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