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Virulence-associated factors in Escherichia coli strains isolated from children with urinary tract infections

Siegfried, L.; Kmetová, M.; Puzová, H.; Molokácová, M.; Filka, J.

Journal of Medical Microbiology 41(2): 127-132

1994


ISSN/ISBN: 0022-2615
PMID: 7913974
DOI: 10.1099/00222615-41-2-127
Accession: 009725371

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One hundred and sixty-eight strains of Escherichia coli were isolated from cases of pyelonephritis (24) and lower urinary tract infections (UTI) (144) from hospitalised and outpatient children up to 2 years old. These strains were investigated for the expression of P fimbriae (PF), mannose-resistant and mannose-sensitive haemagglutination, cell-surface hydrophobicity, serum resistance and the production of alpha-haemolysin (AH), colicins and aerobactin. PF, AH, aerobactin production and serum resistance were significantly more frequent amongst strains expressing mannose-resistant haemagglutination. PF and AH production was significantly more frequent in pyelonephritogenic strains than in lower UTI strains. Serotypes O6 and O112 were isolated most frequently and plasmids were found in the majority of strains tested.

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