EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Antimicrobial chemotherapy of human infection due to Listeria monocytogenes






European Journal of Clinical Microbiology & Infectious Diseases 14(3): 165-175

Antimicrobial chemotherapy of human infection due to Listeria monocytogenes

Listeriosis is an uncommon infection, but when it occurs it carries a high mortality rate. Early diagnosis is essential and thereafter appropriate antimicrobial chemotherapy. Ampicillin or penicillin plus gentamicin remains the treatment of choice for most manifestations of listeriosis, and adequate doses must be given, i.e. greater than 6 g/day of ampicillin or penicillin. Co-trimoxazole appears to be an excellent alternative agent with good penetration into the cerebrospinal fluid. Vancomycin is an appropriate agent for the treatment of primary bacteraemia but does not cross the blood-brain barrier sufficiently well to be useful in meningitis, while erythromycin may be used to treat listeriosis in cases of pregnancy. Treatment of bacteraemia requires one to two weeks' therapy, while meningitis cases may need to be treated for longer; for example, it has been found that most patients with acute meningitis in the UK were treated for 20 days. Infective endocarditis needs treatment for six to eight weeks. Doses should be varied with patients' altered organ function and antimicrobial serum monitoring performed when appropriate.

(PDF 0-2 workdays service: $29.90)

Accession: 009770651

PMID: 7614955



Related references

Potential antimicrobial effects of human lactoferrin against oral infection with Listeria monocytogenes in mice. Journal of Medical Microbiology 54(Pt 11): 1049-1054, 2005

Antimicrobial chemotherapy of meningitis due to Listeria monocytogenes in adults. Journal of Infection 25(1): 119-120, 1992

Serogrouping and pulsed-field gel electrophoresis analysis of Listeria monocytogenes isolates from cases of human infection in Hungary 2004–2012 molecular typing of Listeria monocytogenes in Hungary. Acta Microbiologica et Immunologica Hungarica 61(1): 71-78, 2014

A case of transient Listeria monocytogenes bacteremia recovering without antimicrobial chemotherapy. Kansenshogaku Zasshi. Journal of the Japanese Association for Infectious Diseases 60(1): 76-80, 1986

Spectral differences of Listeria species Separation of the human pathogen Listeria monocytogenes, the non-pathogen Listeria inocua, and the absence of Listeria monocytogenes, in crab meat. Virginia Journal of Science 43(2): 274, 1992

Studies on the pathogenicity of Listeria monocytogenes. I. Protein substance isolated from cells of Listeria monocytogenes enhancing listeric infection. Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-Hygienische Bakteriologie, Virusforschung und Parasitologie. Originale 174(7-8): 573-585, 1959

Transfer of resistance to primary infection of listeria monocytogenes and early induction of delayed hypersensitivity by sera from listeria monocytogenes infected mice. Infection & Immunity 55(12): 3078-3084, 1987

Distribution of Listeria monocytogenes molecular subtypes among human and food isolates from New York State shows persistence of human disease--associated Listeria monocytogenes strains in retail environments. Journal of Food Protection 67(7): 1417-1428, 2004

Some metabolic characteristics of Listeria monocytogenes IV Clouding of the solid medium on egg yolk and on human serum caused by Listeria monocytogenes. 1965

On Some Metabolic Characteristics Of Listeria Monocytogenes. Iv. Turbidity Of Solid Media With Egg Yolk And Human Serum Provoked By Listeria Monocytogenes. Bollettino Dell'istituto Sieroterapico Milanese 44: 15-21, 1965