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Changes of seizure-triggering threshold and after discharge duration in seizure susceptibility

Changes of seizure-triggering threshold and after discharge duration in seizure susceptibility

Brain & Nerve (Tokyo) 44(12): 1103-1106

Epilepsy is analysed on terms of two different conditions, seizure susceptibility and seizure induction. Reports on detailed changes of seizures-triggering threshold and after discharge duration in seizure susceptibility are few. We examined stage changes of seizure-triggering threshold and after discharge duration in seizure susceptibility in a cat amygdaloid kindling model. Ten crossed adult cars were used. We investigated after discharge threshold (ADT), partial seizure threshold (PST) in stage 4 group (P) and generalized seizure threshold (GST) in stage 6 group (C). At the same time, we examined after discharge duration on electroencephalograph (EEG) in each stage. Seizure-triggering threshold decreases significantly step by step. After discharge duration increases significantly step by step. It is concluded that staged decrease of seizure-triggering threshold and increase of seizure's grade and duration was seen in seizure susceptibility.

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Accession: 009789260

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PMID: 1296730

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