+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Parasympathetic innervation of cephalic arteries in rabbits: comparison with sympathetic and sensory innervation

Parasympathetic innervation of cephalic arteries in rabbits: comparison with sympathetic and sensory innervation

Journal of Comparative Neurology 389(3): 484-495

We investigated the distribution of parasympathetic, sympathetic, and sensory perivascular nerve fibers in rabbit cephalic arteries supplying the brain, exocrine glands, nasal mucosa, masseter muscles, tongue, and skin in the face and also examined cranial autonomic and sensory ganglia. NADPH diaphorase (NADPHd)-positive and vasoactive intestinal peptide-like immunoreactive (VIP-LI) neurons were located in the cranial parasympathetic ganglia. Neuropeptide Y (NPY)-LI neurons occurred mainly, and dopamine beta-hydroxylase (DBH)-LI neurons occurred exclusively, in the superior cervical (sympathetic) ganglion. Substance P (SP)-LI and calcitonin gene-related peptide (CGRP)-LI neurons occurred only in the trigeminal (sensory) ganglion. Therefore, it was assumed that NADPHd-positive and VIP-LI perivascular nerve fibers in cephalic arteries were parasympathetic, all DBH-LI and most NPY-LI fibers were sympathetic, and SP-LI and CGRP-LI fibers were sensory in nature. In the cerebral arteries, NADPHd-positive and VIP-LI varicose fibers were more numerous in the rostral than in the caudal half of the Circle of Willis. In the extracranial arteries, NADPHd-positive and VIP-LI fibers were most abundant in the lingual, lacrimal, and supraorbital arteries; sparse in the parotid and submandibular arteries; and absent in the ear artery. There was an obvious proximal-to-distal density gradient along individual cephalic arterial trees. In contrast, DBH-LI, NPY-LI, SP-LI, and CGRP-LI varicose nerve fibers were similar in density in all cephalic arteries and their branches. These neuroanatomical findings suggest that differential parasympathetic innervation in cephalic arteries may play a role in the partitioning of blood flow between different cephalic tissues.

(PDF emailed within 0-6 h: $19.90)

Accession: 009933963

Download citation: RISBibTeXText

PMID: 9414008

DOI: 10.1002/(sici)1096-9861(19971222)389:3<484::aid-cne9>;2-x

Related references

Substance P and the sensory innervation of intracranial and extracranial feline cephalic arteries. Implications for vascular pain mechanisms in man. Brain 108: 517-533, 1985

Parasympathetic, sympathetic, and sensory interactions in the iris: nerve growth factor regulates cholinergic ciliary ganglion innervation in vivo. Journal of Neuroscience 5(10): 2719-2725, 1985

Anatomical and electrophysiological comparison of the sensory innervation of bronchial and tracheal parasympathetic ganglion neurons. Journal Of The Autonomic Nervous System. 61(2): 162-168, 1996

Contributions to the study of the cephalic parasympathetic innervation in galliformes. Institutul Agronomic "Dr Petru Groza" Cluj Lucrari Stiintifice Seria Medicina Veterinara 26: 19-27, 1970

Parasympathetic and sympathetic innervation of the stomach. Anales de la Real Academia Nacional de Medicina 67(3): 383-450, 1950

Innervation of cephalic arteries in the rabbit. Society for Neuroscience Abstracts 21(1-3): 157, 1995

Sympathetic and parasympathetic innervation in hepatocellular carcinoma. Neoplasma 64(6): 840-846, 2017

White adipose tissue lacks significant vagal innervation and immunohistochemical evidence of parasympathetic innervation. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 291(5): R1243-R1255, 2006

NGF synthesis by parasympathetic neurons regulation by sympathetic innervation. Society for Neuroscience Abstracts 26(1-2): Abstract No -221 3, 2000

Sympathetic and parasympathetic innervation of the urinary bladder and urethra. Brain Research 153(2): 363-369, 1978

Parasympathetic and sympathetic innervation of the heart in the developing piglet. Society for Neuroscience Abstracts 15(1): 592, 1989

Parasympathetic excitation of sympathetic innervation after cholinesterase inhibition. British Journal Of Pharmacology. 117(1): 51-54, 1996

Changes of the rat small intestine in disturbance of sympathetic and parasympathetic innervation. Morfologiya 107(7-12): 100-110, 1994

Effect of sympathetic innervation on cephalic and cerebral blood supply. Acta Physiologica Latinoamericana 23(6): 674, 1973

Modulation of parasympathetic neuron phenotype and function by sympathetic innervation. Autonomic Neuroscience Basic & Clinical 96(1): 33-42, 28 February, 2002