+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn

+ Translate
+ Recently Requested

The antiparasitic actions of plant jasmonates



The antiparasitic actions of plant jasmonates



Journal of Parasitology 89(6): 1242-1244



Jasmonates are a group of small lipids produced in plants, which function as plant stress hormones. We have previously shown that jasmonates can exert significant cytotoxic effects upon human cancer cells. The purpose of the present study was to determine the effects of jasmonates on parasites. To that end, we chose 2 major human blood parasites, Plasmodium falciparum, a unicellular parasite, and Schistosoma mansoni, a multicellular helminth parasite, and studied the effects of jasmonates on these parasites in vitro. We found that jasmonates are cytotoxic toward both parasites, with P. falciparum being the more susceptible. Jasmonates did not cause any damage to control human erythrocytes at the maximum concentration used in the experiments. This is the first study demonstrating the antiparasitic potential of plant-derived jasmonates.

(PDF emailed within 0-6 h: $19.90)

Accession: 009995950

Download citation: RISBibTeXText

PMID: 14740919

DOI: 10.1645/GE-94R


Related references

Jasmonates new regulators of plant growth and development many facts and few hypotheses on their actions. Botanica Acta 104(6): 446-454, 1991

The biochemistry and the physiological and molecular actions of jasmonates. Briggs, W R Annual Review of Plant Physiology and Plant Molecular Biology: 569-589, 1993

Balantidium coli, B. caviae, B. wenrichi, using tetracycline, antiparasitic, paromomycin sulfate, antiparasitic, Fur amide, antiparasitic, in pig, guinea pig, spider monkey. Experimental chemotherapy: IV Chemotherapy of neoplastic diseases: I 471-472, 1966

Interactions between jasmonates and abscisic acid in apple fruit, and stimulative effect of jasmonates on anthocyanin accumulation. Journal of the Japanese Society for Horticultural Science 70(5): 546-552, 2001

Jasmonates are essential factors inducing gummosis in tulips: mode of action of jasmonates focusing on sugar metabolism. Journal of Plant Physiology 162(5): 495-505, 2005

Host perception of jasmonates promotes infection by Fusarium oxysporum formae speciales that produce isoleucine- and leucine-conjugated jasmonates. Molecular Plant Pathology 15(6): 589-600, 2015

Secondary actions of antiparasitic products. Revue suisse de viticulture arboriculture horticulture: 7 (1) 5, 1975

Jasmonates: key players in the plant defence. Natural Product Reports 15(6): 533-548, 1999

Jasmonates: key players in the plant defence.. Natural product reports: a journal of current developments in bio organic chemistry 15(6): 533-548, 1998

Jasmonates as signals in plant defense responses. Strauss, M S Unity in Diversity: Pagination varies ABSTRACTS 61, 1995

Jasmonates counter plant stress: A Review. Environmental and Experimental Botany 115: 49-57, 2015

Jasmonates--signals in plant-microbe interactions. Journal of plant growth regulation 23(3): 211-222, 2004

Induction of plant volatiles by herbivores and jasmonates. Biological Chemistry Hoppe-Seyler 376(SPEC SUPPL ): S50, 1995

Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy. Elife 7, 2018

Jasmonates inhibit flowering in short-day plant Pharbitis nil. Plant Growth Regulation 43(1): 1-8, 2004