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A case of chronic neutrophilic leukemia with deletion (11)(q23)



A case of chronic neutrophilic leukemia with deletion (11)(q23)



Cancer Genetics and Cytogenetics 110(1): 70-71



We report a case of chronic neutrophilic leukemia (CNL) in a 68-year-old man. Karyotype showed a clonal abnormality, never described before in CNL: 46,XY,del(11)(q23). Southern blot analysis of the MLL gene did not reveal any rearrangement, and reverse transcriptase polymerase chain reaction (RT-PCR) analysis did not show any fusion of BCR-ABL. Treatment with hydroxyurea and cytosine arabisonide was ineffective.

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Accession: 010049228

Download citation: RISBibTeXText

PMID: 10198627

DOI: 10.1016/s0165-4608(98)00177-0


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