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A potential role for the plasmin(ogen) system in the posttranslational cleavage of the neural cell adhesion molecule L1



A potential role for the plasmin(ogen) system in the posttranslational cleavage of the neural cell adhesion molecule L1



Journal of Cell Science 112: 4739-4749



L1 is a neural recognition molecule that promotes neural developmental and regenerative processes. Posttranslational cleavage of L1 is believed to be important for regulating its function in vivo, but little is known of the proteolytic systems responsible. In this study we present evidence that plasmin can regulate both L1 expression and function.

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Accession: 010087870

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PMID: 10574721


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