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Antenatal magnesium sulphate exposure is associated with prolonged parathyroid hormone suppression in preterm neonates

Antenatal magnesium sulphate exposure is associated with prolonged parathyroid hormone suppression in preterm neonates

Acta Paediatrica 90(3): 278-281

ISSN/ISBN: 0803-5253

PMID: 11332167

DOI: 10.1111/j.1651-2227.2001.tb00304.x

The effects of maternal magnesium sulphate treatment on neonatal mineral status and parathyroid hormone secretory response were studied in 8 exposed and 27 control preterm infants during the first 2 wk of life. Antenatal magnesium sulphate resulted in hypermagnesaemia during the first 3-7 d of life without affecting other serum mineral concentrations. Conclusion: Early hypermagnesaemia was associated with hypercalciuria during the first 3 d and parathyroid hormone suppression up to the age of 2 wk in the exposed infants.

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Accession: 010180189

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