Antimicrobial activities of saponins of pericarps of Sapindus mukurossi on dermatophytes
Tamura, Y.kiyoshi; Mizutani, Kenji; Ikeda, Takao; Ohtani, Kazuhiro; Kasai, Ryoji; Yamasaki, Kazuo; Tanaka, Osamu
Natural Medicines 55(1): 11-16
2001
Accession: 010187011
Monodesmosides of hederagenin from pericarps of Sapindus mukurossi exhibited potent antimicrobial activities on dermatophytes; Epidermophyton floccosum, Trichophyton mentagrophytes, T. rubrum, Sabouraudites canis and Candida albicans. The structure-activity relationship was also studied. The saponins of the pericarps seem to be promising as an ingredient of cosmetics for protection of skin from dermatomycosis.