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Characteristics of immunomodulating effects of polyoxidonium in children with recurrent obstructive bronchitis



Characteristics of immunomodulating effects of polyoxidonium in children with recurrent obstructive bronchitis



Immunologiya (5): 53-55, September-October



Clinicoimmunological examination of 63 children aged 18 months to 6 years with recurrent obstructive bronchitis (ROB) included immunofluorescent assessment of CD3+, CD4+, CD8+, CD16+ and CD19+ cells of peripheral blood, determination of functional activity of phagocytes and levels of IgA, IgG, IgM and IgE. It was found that intramuscular injections of polyoxidonium combined with basic therapy elevate levels of CD3+, CD8+ and CD16+ cells but diminish the level of IgE. This was accompanied by a pronounced clinical effect which transformed to a persistent remission.

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Accession: 010299973

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