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Comparison of immediate and in-hospital results of conventional balloon and perfusion balloon angioplasty using intracoronary ultrasound



Comparison of immediate and in-hospital results of conventional balloon and perfusion balloon angioplasty using intracoronary ultrasound



American Journal of Cardiology 83(3): 311-316, Feb 1



Angiographic studies have demonstrated that perfusion balloon percutaneous transluminal coronary angioplasty (PTCA) may result in modestly improved luminal gains and fewer major dissections than conventional balloon PTCA. However, intracoronary ultrasound (ICUS), which is more sensitive than angiography in evaluating the incidence, extent, and severity of dissection, was not used. We randomized 48 patients with 54 coronary stenoses to conventional or perfusion balloon PTCA. Four 2-minute inflations were permitted with conventional balloon PTCA. Two 10-minute inflations were allowed with perfusion balloon PTCA. Quantitative coronary angiography and ICUS were performed before and after treatment. In-hospital clinical events were recorded. Conventional and perfusion balloon PTCA achieved similar improvements in lumen diameter (1.25 +- 0.51 vs 1.28 +- 0.51 mm) and reductions in percent stenosis (-45 +- 21% vs -44 +- 15%) by quantitative coronary angiography. Comparable gains in lumen diameter (0.62 +- 0.39 Vs 0.50 +- 0.38 mm) and lumen area (2.70 +- 1.96 Vs 2.05 +- 1.52 mm2) were observed on ICUS. Angiography demonstrated similar rates of an), dissection (36% Vs 21%) and major dissection (12% vs 7%). ICUS identified a similar incidence of any dissection (60% Vs 76%) and type II dissection (52% Vs 62%). The relative dissection area was also similar (9.2 +- 5.6% vs 7.8 +- 5.8%). One conventional balloon patient experienced postprocedural chest pain. No patient in either group died, or had myocardial infarction, abrupt closure, or urgent revascularization.

Accession: 010359134

Download citation: RISBibTeXText

PMID: 10072214

DOI: 10.1016/s0002-9149(98)00859-5

Download PDF Full Text: Comparison of immediate and in-hospital results of conventional balloon and perfusion balloon angioplasty using intracoronary ultrasound



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