+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Current advances in the basic research and clinical management of juvenile-onset recurrent respiratory papillomatosis



Current advances in the basic research and clinical management of juvenile-onset recurrent respiratory papillomatosis



European Archives of Oto-Rhino-Laryngology 257(5): 263-269



Juvenile-onset recurrent respiratory papillomatosis is a relatively uncommon disease that presents clinically with symptoms ranging from hoarseness to severe dyspnea. Human papilloma viruses type 6 and 11 are important in the etiology of the papillomata and are most probably transmitted from mother to child during child-birth. Although spontaneous remission is frequent, a rare fatal course because of pulmonary spread or malignant transformation has occurred. CO2 laser evaporation of papillomas and adjuvant drug therapy using lymphoblastoid alpha-interferon are the most common treatment modalities at present. However, several other treatment modalities have been tried with varying success. Recent advances in basic research and different therapeutic approaches are reviewed.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 010402819

Download citation: RISBibTeXText

PMID: 10923940

DOI: 10.1007/s004050050236


Related references

Current status of antiviral therapy for juvenile-onset recurrent respiratory papillomatosis. Antiviral Research 63(3): 141-151, 2004

Operative management of juvenile-onset recurrent respiratory papillomatosis. Operative Techniques in Otolaryngology-Head and Neck Surgery 23(2), 2012

Clinical study of juvenile-onset recurrent respiratory papillomatosis. Zhonghua Er Bi Yan Hou Ke Za Zhi 36(6): 458-462, 2001

Experimental research on the therapeutic effect of MMR vaccine to juvenile-onset recurrent respiratory papillomatosis. European Archives of Oto-Rhino-Laryngology 276(3): 801-803, 2019

Clinical study of tracheotomies children with juvenile onset recurrent respiratory papillomatosis. Lin Chuang Er Bi Yan Hou Ke Za Zhi 20(15): 704-706, 2006

HPV type determination and clinical characteristics in juvenile onset recurrent respiratory papillomatosis. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 30(9): 730-732;736, 2016

Comparison of intravenous general anaesthesia vs endotracheal intubation in the surgical management of juvenile onset recurrent respiratory papillomatosis. Acta Oto-Laryngologica 130(2): 281-285, 2010

Human papillomavirus and host variables as predictors of clinical course in patients with juvenile-onset recurrent respiratory papillomatosis. Journal of Clinical Microbiology 35(12): 3098-3103, 1997

Clinical Activity of Nivolumab for Human Papilloma Virus-Related Juvenile-Onset Recurrent Respiratory Papillomatosis. Oncologist 24(6): 829-835, 2019

Clinical features, health-related quality of life, and adult voice in juvenile-onset recurrent respiratory papillomatosis. Laryngoscope 121(4): 846-851, 2011

Clinical features and surgical treatment for Chinese juvenile onset current respiratory papillomatosis (JORRP). European Archives of Oto-Rhino-Laryngology 274(2): 925-929, 2017

Two cases of juvenile-onset and adult-onset recurrent respiratory papillomatosis. Nihon Kokyuki Gakkai Zasshi 49(9): 667-673, 2011

A comparison of risk factors in juvenile-onset and adult-onset recurrent respiratory papillomatosis. Laryngoscope 102(1): 9, 1992

Juvenile-onset recurrent respiratory papillomatosis. Advances in Oto-Rhino-Laryngology 73: 105-108, 2012

Recurrent Respiratory Papillomatosis (RRP)-Juvenile Onset. Clinical Medicine. Oncology 2: 481-486, 2008