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Development of LTD4 antagonists using QSAR

Development of LTD4 antagonists using QSAR

Agricultural Chemistry & Biotechnology 41(6): 477-482

In order to discover new Leukotriene D4 antagonists, Quantitative Structure-Activity Relationships (QSAR) were applied based on the known data. A series of chalcone derivatives were selected for the training set. A candidate was predicted using QSAR and synthesized, and its biological activity was tested.

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Accession: 010446857

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