+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Evaluation of liquid handling conditions in microplates

Evaluation of liquid handling conditions in microplates

Journal of Biomolecular Screening 6(1): 47-56

Liquid handling in higher density microplates (e.g., 1536-well microplates) for more efficient drug screening necessitates carefully selected and optimized parameters. The quality of a liquid handling procedure is dependent on the carryover rate of residual liquids during the pipetting process, the mixing behavior in the wells, foam and bubble formation, and evaporation. We compared and optimized these parameters in 96-, 384-, and 1536-well microplates, and herein we critically evaluate the performance of the CyBiTM-Well 96/384/1536 automated micropipetting device, which formed the basis of our evaluation studies.

(PDF emailed within 0-6 h: $19.90)

Accession: 010616646

Download citation: RISBibTeXText

PMID: 11679165

DOI: 10.1089/108705701750067024

Related references

Liquid chromatography and ultra-performance liquid chromatography-mass spectrometry fingerprinting of human urine: sample stability under different handling and storage conditions for metabonomics studies. Journal of Chromatography. A 1189(1-2): 314-322, 2007

Parylene mobile microplates integrated with an enzymatic release for handling of single adherent cells. Small 10(5): 912-921, 2014

The development of two oceanic microplates; Easter and Juan Fernandez microplates, East Pacific Rise. Journal of the Geological Society of London: Part 5; Pages 965-976. 1993., 1993

Development of SCEPTER 1.5 ASU formulation by evaluation of liquid handling properties. Pesticide formulations and application systems: seventh volume: a symposium sponsored by ASTM Committee E 35 on Pesticides Phoenix Ariz 5-6 Nov 1986 GB Beestman and DIB Vander Hooven editors: 2, 1987

Microplates based on liquid bridges between glass rods. Journal of Colloid and Interface Science 397: 177-184, 2013

Microplates in liquid chromatography--new solution in clinical research? A review. Talanta 115: 973-979, 2014

A fast optical method for the determination of liquid levels in microplates. Journal of Automated Methods & Management in Chemistry 2011: 805153-805153, 2011

Modeling the liquid filling in capillary well microplates for analyte preconcentration. Journal of Colloid and Interface Science 376(1): 269-273, 2012

Synthesis of gold nano- and microplates in hexagonal liquid crystals. Journal of Physical Chemistry. B 109(8): 3189-3194, 2006

Evaluation of metalloendopeptidase Lys-N protease performance under different sample handling conditions. Journal of Proteome Research 9(8): 4282-4288, 2010

Microfluidics on liquid handling stations (μF-on-LHS): an industry compatible chip interface between microfluidics and automated liquid handling stations. Lab on A Chip 13(12): 2337-2343, 2013

Evaluation of an automated liquid-handling system (Tecan Genesis RSP 100) in the Abbott LCx assay for Chlamydia trachomatis. Journal of Clinical Microbiology 39(5): 1975-1977, 2001

Aqueous-biamphiphilic ionic liquid systems: self-assembly and synthesis of gold nanocrystals/microplates. Journal of Physical Chemistry. B 116(49): 14363-14374, 2013

Verification of multichannel liquid dispenser performance in the 4-30 muL range by using optical pathlength measurements in microplates. Clinical Chemistry 44(10): 2206-2208, 1998

Hygienic evaluation of the working conditions of operators handling universal turning lathes. Gigiena Truda i Professional'nye Zabolevaniia: 26-29, 1980