EurekaMag
+ Translate
+ Most Popular
Gaucher's disease;thirty-two years experience at Siriraj Hospital
A study of Macrobathra Meyrick from China (Lepidoptera, Cosmopterigidae)
First occurrence in ores of tetragonal chalcocite
Effects of trace element nutrition on sleep patterns in adult women
N.Z. range management guidelines. 2. Design of grazing management systems for tussock country
A case of lipoma of the esophagus
A revision of world Acanthosomatidae (Heteroptera: Pentatomidae): keys to and descriptions of subfamilies, tribes and genera, with designation of types
Life history of the coronate scyphozoan Linuche unguiculata (Swartz, 1788)
Perceptual restoration of obliterated sounds
Mutagenicity studies on two chromium(III) coordination compounds
The formation of the skeleton. I. Growth of a long bone. 1st appearance of a center of calcification
Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis
The joint commission: four key root causes loom large in sentinel event data
Treatment of vitiligo with topical 15% lactic acid solution in combination with ultra violet-A
Behaviour of dairy cows within three hours after feed supply: I. Influence of housing type and time elapsing after feed supply
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Management and control of patients with type 2 diabetes mellitus in Lebanon: results from the International Diabetes Management Practices Study (IDMPS)
The diet composition and nutritional knowledge of patients with anorexia nervosa
Physoporella croatica Herak, 1958 of the Slovak karst Anisian (Slovakia, the West Carpathians Mts.)
Bright lights, big noise. How effective are vehicle warning systems?
Ein Plesiosaurier-Rest mit Magensteinen aus mittlerem Lias von Quedlinburg
Incidence of Chlamydia trachomatis in patients with sterility
Monster soup: the microscope and Victorian fantasy
Preliminary tests with residual sprays against poultry lice
Duration of the life of plants in phylogeny

HpkA, a histidine protein kinase homolog, is required for fruiting body development in Myxococcus xanthus


HpkA, a histidine protein kinase homolog, is required for fruiting body development in Myxococcus xanthus



Journal of Microbiology and Biotechnology 13(3): 400-405



ISSN/ISBN: 1017-7825

A gene (hpkA), encoding a histidine protein kinase homolog, has been identified in the upstream region of the espAB operon in Myxococcus xanthus. It encodes a 333 amino acid (35,952 Da) protein with a histidine protein kinase domain in the region from amino acid 90 to 317. Null mutations in the hpkA gene caused formation of loose irregular fruiting bodies, while wild-type strains developed tight hemispherical fruiting bodies under developmental conditions. Sporulation of the hpkA mutant was delayed by at least 12 h compared to that of the wild-type. It appeared that the hpkA mutation increased the expression of the espAB operon by more than 2-fold compared with the wild-type under developmental conditions. Expression of the hpkA gene was low under vegetative conditions, but was highly induced under developmental conditions.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 010763669

Download citation: RISBibTeXText

Related references

Identification and characterization of a putative arginine kinase homolog from Myxococcus xanthus required for fruiting body formation and cell differentiation. Journal of Bacteriology 194(10): 2668-2676, 2012

TodK, a putative histidine protein kinase, regulates timing of fruiting body morphogenesis in Myxococcus xanthus. Journal of Bacteriology 185(18): 5452-5464, 2003

Identification of an activator protein required for the induction of fruA, a gene essential for fruiting body development in Myxococcus xanthus. Proceedings of the National Academy of Sciences of the United States of America 100(15): 8782-8787, 2003

Operon required for fruiting body development in Myxococcus xanthus. Journal of Microbiology and Biotechnology 19(11): 1288-1294, 2009

SdeK, a histidine kinase required for Myxococcus xanthus development. Journal of Bacteriology 183(12): 3589-3596, 2001

SdeK is required for early fruiting body development in Myxococcus xanthus. Journal of Bacteriology 180(17): 4628-4637, 1998

Four signalling domains in the hybrid histidine protein kinase RodK of Myxococcus xanthus are required for activity. Molecular Microbiology 60(2): 525-534, 2006

The DevT protein stimulates synthesis of FruA, a signal transduction protein required for fruiting body morphogenesis in Myxococcus xanthus. Journal of Bacteriology 184(6): 1540-1546, 2002

A CheW homologue is required for Myxococcus xanthus fruiting body development, social gliding motility, and fibril biogenesis. Journal of Bacteriology 184(20): 5654-5660, 2002

A DnaK homolog in Myxococcus xanthus is involved in social motility and fruiting body formation. Journal of Bacteriology 180(2): 218-224, 1998

Myxococcus xanthus mokA encodes a histidine kinase-response regulator hybrid sensor required for development and osmotic tolerance. Journal of Bacteriology 183(4): 1140-1146, 2001

Two intercellular signals required for fruiting body formation in Myxococcus xanthus act sequentially but non-hierarchically. Molecular Microbiology 86(1): 65-81, 2012

The Myxococcus xanthus Nla4 protein is important for expression of stringent response-associated genes, pp Gpp accumulation, and fruiting body development. Journal of bacteriology 189(23): 8474-8483, 2007

Developmental expression of dnaA is required for sporulation and timing of fruiting body formation in Myxococcus xanthus. Molecular Microbiology 76(5): 1322-1333, 2010

Myxococcus xanthus sasS encodes a sensor histidine kinase required for early developmental gene expression. Journal of Bacteriology 179(24): 7759-7767, 1997