+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Identification of Prevotella in pedal osteomyelitis of a diabetic patient

Identification of Prevotella in pedal osteomyelitis of a diabetic patient

Ultrastructural Pathology 27(4): 271-283, July-August

Osteomyelitis in a diabetic patient with a nonhealing foot ulcer, multiple medical conditions, and recurrent hospitalization for antibiotic therapy was found to be associated with gram-negative bacteria Prevotella melanginoganica and Prevotella melaninoganica hemagglutinating variant. Those organisms were identified due to the morphologically distinct features in electron microscopy and sequencing of the genes after Polymerase chain reaction amplification from the pathological material. The bacteria invaded the bone and resided in osteocyte, osteoblast, and endothelial cells. The bacteria are usually associated with periodontal plaques, causing inflammation and destruction of gingival tissue and resorption of the alveolar bone. This is the first ultrastructural and molecular study of a diabetic bone lesion with anaerobic bacterial infection.

(PDF emailed within 0-6 h: $19.90)

Accession: 010781843

Download citation: RISBibTeXText

PMID: 12907373

DOI: 10.1080/01913120309918

Related references

The diagnosis of pedal osteomyelitis in diabetic patients. Diabetologia 41(SUPPL 1): A276, 1998

Prognostic value of 99m Tc leukocyte scintigraphy in diabetic pedal osteomyelitis. Foot & Ankle International 22(9): 720-724, 2001

Antibiotic beads in the treatment of diabetic pedal osteomyelitis. Journal of Foot and Ankle Surgery 39(2): 124-130, 2000

Current concepts in imaging diabetic pedal osteomyelitis. Radiologic Clinics of North America 46(6): 1105-24, Vii, 2008

Differential diagnosis of pedal osteomyelitis and diabetic neuroarthropathy: MR Imaging. Seminars in Musculoskeletal Radiology 9(3): 272-283, 2005

Diabetic pedal osteomyelitis diagnostic efficacy of indium 111 wbc imaging. Journal of Nuclear Medicine 32(5 SUPPL): 963, 1991

Diagnosis of pedal osteomyelitis in diabetic patients using current scintigraphic techniques. Archives of Internal Medicine 149(10): 2262-2266, 1989

Rare mimic of pedal osteomyelitis in a patient with diabetes. Diabetic Medicine 33(11): E30-E31, 2015

Probing to bone in infected pedal ulcers. A clinical sign of underlying osteomyelitis in diabetic patients. JAMA 273(9): 721-723, 1995

Mild-to-moderate hyperglycemia will not decrease the sensitivity of 18F-FDG PET imaging in the detection of pedal osteomyelitis in diabetic patients. Nuclear Medicine Communications 37(3): 259-262, 2016

Pedal abscesses in patients suspected of having pedal osteomyelitis: analysis with MR imaging. Radiology 224(3): 649-655, 2002

Feasibility and effectiveness of internal pedal amputation of phalanx or metatarsal head in diabetic patients with forefoot osteomyelitis. Journal of Foot and Ankle Surgery 51(5): 593-598, 2013

Phenotypic diversity among ruminal isolates of Prevotella ruminicola: proposal of Prevotella brevis sp. nov., Prevotella bryantii sp. nov., and Prevotella albensis sp. nov. and redefinition of Prevotella ruminicola. International Journal of Systematic Bacteriology 47(2): 284-288, 1997

Emended descriptions of Prevotella denticola, Prevotella loescheii, Prevotella veroralis, and Prevotella melaninogenica. International Journal of Systematic Bacteriology 42(4): 536-541, 1992