+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Implications of a high placental ratio in pregnancies with appropriate-for-gestational age neonates

Implications of a high placental ratio in pregnancies with appropriate-for-gestational age neonates

Gynecologic and Obstetric Investigation 52(1): 34-37

Objective: To determine the relationship between the placental weight to birth weight ratio (placental ratio) with maternal pre-pregnancy weight, gestational weight gain, and neonatal outcome in non-diabetic pregnancies resulting in appropriate-for-gestational age (AGA) infants. Methods: A retrospective study was performed on 593 patients with singleton pregnancies, normal results in the 75-gram oral glucose tolerance test and who delivered AGA newborns within a 1-year period. The patients were categorized into high placental ratio (>mean+1 SD based on previous data, n=113 or 19.1%) and normal ratio groups for the comparison of maternal and neonatal anthropometric parameters. Results: The high placental ratio group had a higher pre-pregnancy weight, body mass index, placental weight, and incidence of low Apgar score, but decreased absolute and percentage gestational weight gain, gestational age, and birth weight. After controlling for pre-pregnancy weight and gestational age, only the correlation between placental weight and percent weight gain remained significant. Conclusion: Our finding suggests that a high placental ratio can identify AGA newborns who are disproportionately small relative to maternal size, and may reflect some form of fetal growth impairment.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 010805557

Download citation: RISBibTeXText

PMID: 11549861

Related references

Implications of a High Placental Ratio in Pregnancies with Appropriate-for-Gestational Age Neonates. Gynecologic and Obstetric Investigation 52(1): 34-37, 2001

The neonatal implications of a high placental ratio in small-for-gestational age infants. Placenta 20(8): 723-726, 1999

Of pregnancies complicated by small for gestational age babies at term, what proportions have placental findings with implications for future pregnancies or neonatal outcomes?. Journal of Maternal-Fetal and Neonatal Medicine 2019: 1-6, 2019

Maternal serum placental growth hormone at 11-13 weeks' gestation in pregnancies delivering small for gestational age neonates. Journal of Maternal-Fetal and Neonatal Medicine 25(9): 1796-1799, 2012

Soluble fms-like tyrosine kinase 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates: relationship to circulating placental growth factor. Journal of Clinical Endocrinology and Metabolism 90(8): 4895-4903, 2005

The significance of placental ratios in pregnancies complicated by small for gestational age, preeclampsia, and gestational diabetes mellitus. Obstetrics and Gynecology Science 57(5): 358-366, 2014

Micromanaging human placental function: differential microRNA expression in feto-placental endothelial cells of gestational diabetes pregnancies. Clinical Science 133(2): 315-319, 2019

Increased maternal insulin resistance promotes placental growth and decreases placental efficiency in pregnancies with obesity and gestational diabetes mellitus. Journal of Obstetrics and Gynaecology Research 44(1): 74-80, 2018

Paternal age, placental weight and placental to birthweight ratio: a population-based study of 590,835 pregnancies. Human Reproduction 28(11): 3126-3133, 2013

Use of placental vascularization indices and uterine artery peak systolic velocity in early detection of pregnancies complicated by gestational diabetes, chronic or gestational hypertension, and preeclampsia at risk. Croatian Medical Journal 58(2): 161-169, 2017

Maternal and umbilical cord serum leptin concentrations in small-for-gestational-age and in appropriate-for-gestational-age neonates: a maternal, fetal, or placental contribution?. Biology of the Neonate 84(1): 67-72, 2003

Maternal and Umbilical Cord Serum Leptin Concentrations in Small-for-Gestational-Age and in Appropriate-for-Gestational-Age Neonates: A Maternal, Fetal, or Placental Contribution?. Neonatology 84(1): 67-72, 2003

Placental weight, birth weight and fetal:placental weight ratio in dichorionic and monochorionic twin gestations in function of gestational age, cord insertion type and placental partition. Placenta 36(2): 213-220, 2015

Serum medians for placental proteins in pregnancies achieved by IVF are different from those of spontaneous pregnancies Implications for fetal trisomy screening. Human Reproduction 15(Abstract Book 1): 171, 2000

Ovulation induction and small for gestational age neonates in twin pregnancies. Journal of Neonatal-Perinatal Medicine 6(3): 217-224, 2013