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Implications of a high placental ratio in pregnancies with appropriate-for-gestational age neonates



Implications of a high placental ratio in pregnancies with appropriate-for-gestational age neonates



Gynecologic and Obstetric Investigation 52(1): 34-37



Objective: To determine the relationship between the placental weight to birth weight ratio (placental ratio) with maternal pre-pregnancy weight, gestational weight gain, and neonatal outcome in non-diabetic pregnancies resulting in appropriate-for-gestational age (AGA) infants. Methods: A retrospective study was performed on 593 patients with singleton pregnancies, normal results in the 75-gram oral glucose tolerance test and who delivered AGA newborns within a 1-year period. The patients were categorized into high placental ratio (>mean+1 SD based on previous data, n=113 or 19.1%) and normal ratio groups for the comparison of maternal and neonatal anthropometric parameters. Results: The high placental ratio group had a higher pre-pregnancy weight, body mass index, placental weight, and incidence of low Apgar score, but decreased absolute and percentage gestational weight gain, gestational age, and birth weight. After controlling for pre-pregnancy weight and gestational age, only the correlation between placental weight and percent weight gain remained significant. Conclusion: Our finding suggests that a high placental ratio can identify AGA newborns who are disproportionately small relative to maternal size, and may reflect some form of fetal growth impairment.

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Accession: 010805557

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PMID: 11549861


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