EurekaMag PDF full texts Chapter 10,868

Reynolds, G.M.; Billingham, L.J.; Gray, L.J.; Flavell, J.R.; Najafipour, S.; Crocker, J.; Nelson, P.; Young, L.S.; Murray, P.G. 2002: Interleukin 6 expression by Hodgkin/Reed-Sternberg cells is associated with the presence of 'B' symptoms and failure to achieve complete remission in patients with advanced Hodgkin's disease. British Journal of Haematology 118(1): 195-201

Hojo, Y.; Ikeda, U.; Katsuki, T.; Mizuno, O.; Fukazawa, H.; Kurosaki, K.; Fujikawa, H.; Shimada, K. 2000: Interleukin 6 expression in coronary circulation after coronary angioplasty as a risk factor for restenosis. Heart 84(1): 83-87

Collado-Escobar, M.D.; Nieto, A.; Matarán, L.; Raya, E.; Martín, J. 2000: Interleukin 6 gene promoter polymorphism is not associated with ankylosing spondylitis. Journal of Rheumatology 27(6): 1461-1463

Fujimori, K.; Itoh, Y.; Yamamoto, K.; Miyagoe-Suzuki, Y.; Yuasa, K.; Yoshizaki, K.; Yamamoto, H.; Takeda, S.'i. 2002: Interleukin 6 induces overexpression of the sarcolemmal utrophin in neonatal mdx skeletal muscle. Human Gene Therapy 13(4): 509-518

Kopf, M.; Herren, S.; Wiles, M.V.; Pepys, M.B.; Kosco-Vilbois, M.H. 1998: Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component. Journal of Experimental Medicine 188(10): 1895-1906

Badache, A.; Hynes, N.E. 2001: Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells. Cancer Research 61(1): 383-391

Blindenbacher, A.; Wang, X.; Langer, I.; Savino, R.; Terracciano, L.; Heim, M.H. 2003: Interleukin 6 is important for survival after partial hepatectomy in mice. Hepatology 38(3): 674-682

Boe, A.; Baiocchi, M.; Carbonatto, M.; Papoian, R.; Serlupi-Crescenzi, O. 1999: Interleukin 6 knock-out mice are resistant to antigen-induced experimental arthritis. Cytokine 11(12): 1057-1064

Fee, D.; Grzybicki, D.; Dobbs, M.; Ihyer, S.; Clotfelter, J.; Macvilay, S.; Hart, M.N.; Sandor, M.; Fabry, Z. 2000: Interleukin 6 promotes vasculogenesis of murine brain microvessel endothelial cells. Cytokine 12(6): 655-665

Minamiguchi, H.; Yahata, N.; Kimura, T.; Fujiki, H.; Harada, S.; Wang, J.; Okuda, K.; Kaneko, H.; Hodohara, K.; Banba, T.; Yasukawa, K.; Ohyashiki, J.H.; Ohyashiki, K.; Abe, T.; Sonoda, Y. 2000: Interleukin 6 receptor expression by human cord blood- or peripheral blood-derived primitive haematopoietic progenitors implies acquisition of different functional properties. British Journal of Haematology 110(2): 327-338

Pietruski, J.K.; Pietruska, M.D.; Jabłońska, E.; Sacha, P.; Zaremba, M.; Stokowska, W. 2000: Interleukin 6, tumor necrosis factor alpha and their soluble receptors in the blood serum of patients with denture stomatitis and fungal infection. Archivum Immunologiae et Therapiae Experimentalis 48(2): 101-105

Zheng, C.; Huang, D.R.; Bergenbrant, S.; Sundblad, A.; Osterborg, A.; Björkholm, M.; Holm, G.; Yi, Q. 2000: Interleukin 6, tumour necrosis factor alpha, interleukin 1beta and interleukin 1 receptor antagonist promoter or coding gene polymorphisms in multiple myeloma. British Journal of Haematology 109(1): 39-45

Streetz, K.L.; Tacke, F.; Leifeld, L.; Wüstefeld, T.; Graw, A.; Klein, C.; Kamino, K.; Spengler, U.; Kreipe, H.; Kubicka, S.; Müller, W.; Manns, M.P.; Trautwein, C. 2003: Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases. Hepatology 38(1): 218-229

Herity, N.A. 2000: Interleukin 6: a message from the heart. Heart 84(1): 9-10

Ross, F.Patrick. 2003: Interleukin 7 and estrogen-induced bone loss. Trends in Endocrinology and Metabolism: Tem 14(4): 147-149

Sin, J.I.; Kim, J.; Pachuk, C.; Weiner, D.B.; Patchuk, C. 2000: Interleukin 7 can enhance antigen-specific cytotoxic-T-lymphocyte and/or Th2-type immune responses in vivo. Clinical and Diagnostic Laboratory Immunology 7(5): 751-758

Bebo, B.F.; Schuster, J.C.; Adlard, K.; Vandenbark, A.A.; Offner, H. 2000: Interleukin 7 is a potent co-stimulator of myelin specific T cells that enhances the adoptive transfer of experimental autoimmune encephalomyelitis. Cytokine 12(4): 324-331

Isgrò, A.; Aiuti, F.; Mezzaroma, I.; Franchi, F.; Mazzone, A.M.; Lebba, F.; Aiuti, A. 2002: Interleukin 7 production by bone marrow-derived stromal cells in HIV-1-infected patients during highly active antiretroviral therapy. Aids 16(16): 2231-2232

Durum, S.K.; Candèias, S.; Nakajima, H.; Leonard, W.J.; Baird, A.M.; Berg, L.J.; Muegge, K. 1998: Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility. Journal of Experimental Medicine 188(12): 2233-2241

van Roon, J.A.G.; Glaudemans, K.A.F.M.; Bijlsma, J.W.J.; Lafeber, F.P.J.G. 2003: Interleukin 7 stimulates tumour necrosis factor alpha and Th1 cytokine production in joints of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases 62(2): 113-119

Sinha, M.L.; Fry, T.J.; Fowler, D.H.; Miller, G.; Mackall, C.L. 2002: Interleukin 7 worsens graft-versus-host disease. Blood 100(7): 2642-2649

Retzlaff, S.; Padró, T.; Koch, P.; Oelmann, E.; Lügering, N.; Mesters, R.M.; Berdel, W.E. 2002: Interleukin 8 and Flt3 ligand as markers of advanced disease in primary gastrointestinal non-Hodgkin's lymphoma. Oncology Reports 9(3): 525-527

De Benedetti, F.; Pignatti, P.; Bernasconi, S.; Gerloni, V.; Matsushima, K.; Caporali, R.; Montecucco, C.M.; Sozzani, S.; Fantini, F.; Martini, A. 1999: Interleukin 8 and monocyte chemoattractant protein-1 in patients with juvenile rheumatoid arthritis. Relation to onset types, disease activity, and synovial fluid leukocytes. Journal of Rheumatology 26(2): 425-431

Kido, S.; Kitadai, Y.; Hattori, N.; Haruma, K.; Kido, T.; Ohta, M.; Tanaka, S.; Yoshihara, M.; Sumii, K.; Ohmoto, Y.; Chayama, K. 2001: Interleukin 8 and vascular endothelial growth factor -- prognostic factors in human gastric carcinomas?. European Journal of Cancer 37(12): 1482-1487

Van Aken, B.E.; Reitsma, P.H.; Rosendaal, F.R. 2002: Interleukin 8 and venous thrombosis: Evidence for a role of inflammation in thrombosis. British Journal of Haematology 116(1): 173-177

Gonçalves, M.S.; Queiroz, I.L.; Cardoso, S.A.; Zanetti, A.; Strapazoni, A.C.; Adorno, E.; Albuquerque, A.; Sant'Ana, A.; dos Reis, M.G.; Barral, A.; Barral Netto, M. 2001: Interleukin 8 as a vaso-occlusive marker in Brazilian patients with sickle cell disease. Brazilian Journal of Medical and Biological Research 34(10): 1309-1313

Elliott, C.L.; Slater, D.M.; Dennes, W.; Poston, L.; Bennett, P.R. 2000: Interleukin 8 expression in human myometrium: Changes in relation to labor onset and with gestational age. American Journal of Reproductive Immunology 43(5): 272-277

Amoli, M.M.; Thomson, W.; Hajeer, A.H.; Calviño, M.C.; Garcia-Porrua, C.; Ollier, W.E.R.; Gonzalez-Gay, M.A. 2002: Interleukin 8 gene polymorphism is associated with increased risk of nephritis in cutaneous vasculitis. Journal of Rheumatology 29(11): 2367-2370

Leibovitz, E.; Dagan, R.; Laver, J.H.; Piglansky, L.; Raiz, S.; Abboud, M.R.; Fliss, D.M.; Leiberman, A.; Barzilai, A. 2000: Interleukin 8 in middle ear fluid during acute otitis media: correlation with aetiology and bacterial eradication. Archives of Disease in Childhood 82(2): 165-168

Takasaki, J.; Ogawa, Y. 1999: Interleukin 8 in the tracheobronchial aspirate of infants acts as a neutrophil chemotactic factor in the development of chronic lung disease. Pediatrics International: Official Journal of the Japan Pediatric Society 41(1): 78-81

Senturk, L.M.; Sozen, I.; Gutierrez, L.; Arici, A. 2001: Interleukin 8 production and interleukin 8 receptor expression in human myometrium and leiomyoma. American Journal of Obstetrics and Gynecology 184(4): 559-566

Marie, C.; Fitting, C.; Muret, J.; Payen, D.; Cavaillon, J.M. 2000: Interleukin 8 production in whole blood assays: Is interleukin 10 responsible for the downregulation observed in sepsis?. Cytokine 12(1): 55-61

Frendéus, B.; Godaly, G.; Hang, L.; Karpman, D.; Lundstedt, A.C.; Svanborg, C. 2000: Interleukin 8 receptor deficiency confers susceptibility to acute experimental pyelonephritis and may have a human counterpart. Journal of Experimental Medicine 192(6): 881-890

Gómez-Quiroz, L.; Bucio, L.; Souza, Vónica.; Escobar, C.; Farfán, B.; Hernández, E.; Konigsberg, M.; Vargas-Vorackova, F.; Kershenobich, D.; Gutiérrez-Ruiz, M.Concepción. 2003: Interleukin 8 response and oxidative stress in HepG2 cells treated with ethanol, acetaldehyde or lipopolysaccharide. Hepatology Research: the Official Journal of the Japan Society of Hepatology 26(2): 134-141

Katancik, J.A.; Sharma, A.; de Nardin, E. 2000: Interleukin 8, neutrophil-activating peptide-2 and GRO-alpha bind to and elicit cell activation via specific and different amino acid residues of CXCR2. Cytokine 12(10): 1480-1488

Galffy, G.; Mohammed, K.A.; Dowling, P.A.; Nasreen, N.; Ward, M.J.; Antony, V.B. 1999: Interleukin 8: an autocrine growth factor for malignant mesothelioma. Cancer Research 59(2): 367-371

Lejeune, D.; Demoulin, J.-Baptiste; Renauld, J.-Christophe 2001: Interleukin 9 induces expression of three cytokine signal inhibitors: Cytokine-inducible SH2-containing protein, suppressor of cytokine signalling (SOCS)-2 and SOCS-3, but only SOCS-3 overexpression suppresses interleukin 9 signalling. Biochemical Journal 353(1): 109-116

Louahed, J.; Zhou, Y.; Maloy, W.L.; Rani, P.U.; Weiss, C.; Tomer, Y.; Vink, A.; Renauld, J.; Van Snick, J.; Nicolaides, N.C.; Levitt, R.C.; Haczku, A. 2001: Interleukin 9 promotes influx and local maturation of eosinophils. Blood 97(4): 1035-1042

Vink, A.; Warnier, G.; Brombacher, F.; Renauld, J.C. 1999: Interleukin 9-induced in vivo expansion of the B-1 lymphocyte population. Journal of Experimental Medicine 189(9): 1413-1423

Reich, M.; Zwacka, G.; Markert, U.R. 2002: Interleukin ELISPOT assay for evaluation of specific sublingual immunotherapy in allergy. International Journal of Immunotherapy 18(2): 53-56

Treszl, A.ás.; Tóth-Heyn, P.ét.; Kocsis, I.án.; Nobilis, A.ás.; Schuler, A.; Tulassay, T.; Vásárhelyi, B. 2002: Interleukin genetic variants and the risk of renal failure in infants with infection. Pediatric Nephrology 17(9): 713-717

Iwata, M.; Vieira, J.; Byrne, M.; Horton, H.; Torok-Storb, B. 1999: Interleukin-1 (IL-1) inhibits growth of cytomegalovirus in human marrow stromal cells: inhibition is reversed upon removal of IL-1. Blood 94(2): 572-578

Takaesu, G.; Ninomiya-Tsuji, J.; Kishida, S.; Li, X.; Stark, G.R.; Matsumoto, K. 2001: Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway. Molecular and Cellular Biology 21(7): 2475-2484

Jiang, Z.; Ninomiya-Tsuji, J.; Qian, Y.; Matsumoto, K.; Li, X. 2002: Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol. Molecular and Cellular Biology 22(20): 7158-7167

Murphy, J.E.; Robert, C.; Kupper, T.S. 2000: Interleukin-1 and cutaneous inflammation: a crucial link between innate and acquired immunity. Journal of Investigative Dermatology 114(3): 602-608

Boraschi, D.; Tagliabue, A. 1999: Interleukin-1 and interleukin-1 fragments as vaccine adjuvants. Methods 19(1): 108-113

Rothwell, N. 2003: Interleukin-1 and neuronal injury: Mechanisms, modification, and therapeutic potential. Brain Behavior and Immunity 17(3): 152-157

Mrak, R.E.; Griffin, W.S. 2000: Interleukin-1 and the immunogenetics of Alzheimer disease. Journal of Neuropathology and Experimental Neurology 59(6): 471-476

Chiang, C.Y.; Kyritsis, G.; Graves, D.T.; Amar, S. 1999: Interleukin-1 and tumor necrosis factor activities partially account for calvarial bone resorption induced by local injection of lipopolysaccharide. Infection and Immunity 67(8): 4231-4236

Perrien, D.S.; Brown, E.C.; Fletcher, T.W.; Irby, D.J.; Aronson, J.; Gao, G.G.; Skinner, R.A.; Hogue, W.R.; Feige, U.; Suva, L.J.; Ronis, M.J.J.; Badger, T.M.; Lumpkin, C.K. 2002: Interleukin-1 and tumor necrosis factor antagonists attenuate ethanol-induced inhibition of bone formation in a rat model of distraction osteogenesis. Journal of Pharmacology and Experimental Therapeutics 303(3): 904-908

Graves, D.T.; Delima, A.J.; Assuma, R.; Amar, S.; Oates, T.; Cochran, D. 1998: Interleukin-1 and tumor necrosis factor antagonists inhibit the progression of inflammatory cell infiltration toward alveolar bone in experimental periodontitis. Journal of Periodontology 69(12): 1419-1425

Chen, C.P.; Hertzberg, M.; Jiang, Y.; Graves, D.T. 1999: Interleukin-1 and tumor necrosis factor receptor signaling is not required for bacteria-induced osteoclastogenesis and bone loss but is essential for protecting the host from a mixed anaerobic infection. American Journal of Pathology 155(6): 2145-2152

Serou, M.J.; Decoster, M.A.; Bazan, N.G. 1999: Interleukin-1 beta activates expression of cyclooxygenase-2 and inducible nitric oxide synthase in primary hippocampal neuronal culture: Platelet-activating factor as a preferential mediator of cyclooxygenase-2 expression. Journal of Neuroscience Research 58(4): 593-598

Conti, G.; De Pol, A.; Scarpini, E.; Vaccina, F.; De Riz, M.; Baron, P.; Tiriticco, M.; Scarlato, G. 2002: Interleukin-1 beta and interferon-gamma induce proliferation and apoptosis in cultured Schwann cells. Journal of Neuroimmunology 124(1-2): 29-35

Papadimas, J.; Goulis, D.G.; Sotiriades, A.; Daniilidis, M.; Fleva, A.; Bontis, J.N.; Tourkantonis, A. 2002: Interleukin-1 beta and tumor necrosis factor-alpha in normal/infertile men. Archives of Andrology 48(2): 107-113

Shi, J.; Han, Y.; Sun, G. 1999: Interleukin-1 beta gene expression in neonate rats after hypoxia-ischemic brain damage. Journal of China Medical University 28(2): 83-84

Tsai, C.C.; Chen, C.C.; Lin, C.C.; Chen, C.H.; Lin, T.S.; Shieh, T.Y. 1999: Interleukin-1 beta in oral submucous fibrosis, verrucous hyperplasia and squamous cell carcinoma tissues. Kaohsiung Journal of Medical Sciences 15(9): 513-519

Hulkkonen, J.; Vilpo, J.; Vilpo, L.; Koski, T.; Hurme, M. 2000: Interleukin-1 beta, interleukin-1 receptor antagonist and interleukin-6 plasma levels and cytokine gene polymorphisms in chronic lymphocytic leukemia: correlation with prognostic parameters. Haematologica 85(6): 600-606

Honegger, A.E.; Hofer, E.L.; Barañao, R.I.; Mackinlay, T.A.; Mackinlay, D.A.; Bullorsky, E.O.; Bordenave, R.H.; Chasseing, N.A. 2002: Interleukin-1 beta, transforming growth factor beta 1, prostaglandin E2, and fibronectin levels in the conditioned mediums of bone marrow fibroblast cultures from lung and breast cancer patients. Annals of Hematology 81(2): 80-85

Antin, J.H.; Weisdorf, D.; Neuberg, D.; Nicklow, R.; Clouthier, S.; Lee, S.J.; Alyea, E.; McGarigle, C.; Blazar, B.R.; Sonis, S.; Soiffer, R.J.; Ferrara, J.L.M. 2002: Interleukin-1 blockade does not prevent acute graft-versus-host disease: results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation. Blood 100(10): 3479-3482

Miller, L.J.; Kurtzman, S.H.; Anderson, K.; Wang, Y.; Stankus, M.; Renna, M.; Lindquist, R.; Barrows, G.; Kreutzer, D.L. 2000: Interleukin-1 family expression in human breast cancer: Interleukin-1 receptor antagonist. Cancer Investigation 18(4): 293-302

Vohnout, B.; Di Castelnuovo, A.; Trotta, R.; D'Orazi, A.; Panniteri, G.; Montali, A.; Donati, M.Benedetta.; Arca, M.; Iacoviello, L. 2003: Interleukin-1 gene cluster polymorphisms and risk of coronary artery disease. Haematologica 88(1): 54-60

Um, J-Young.; Moon, K-Suk.; Lee, K-Min.; Kim, H-Min. 2003: Interleukin-1 gene cluster polymorphisms in cerebral infarction. Cytokine 23(1-2): 41-46

Hutyrová, B.; Pantelidis, P.; Drábek, J.í; Zůrková, M.; Kolek, V.ít.; Lenhart, K.; Welsh, K.I.; Du Bois, R.M.; Petrek, M. 2002: Interleukin-1 gene cluster polymorphisms in sarcoidosis and idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine 165(2): 148-151

Zhang, X.; Llamado, L.; Pillay, I.; Price, P.; Will, R. 2002: Interleukin-1 gene polymorphism disease activity and bone mineral metabolism in rheumatoid arthritis. Chinese Medical Journal 115(1): 46-49

De Sanctis, M.; Zucchelli, G. 2000: Interleukin-1 gene polymorphisms and long-term stability following guided tissue regeneration therapy. Journal of Periodontology 71(4): 606-613

McDevitt, M.J.; Wang, H.Y.; Knobelman, C.; Newman, M.G.; di Giovine, F.S.; Timms, J.; Duff, G.W.; Kornman, K.S. 2000: Interleukin-1 genetic association with periodontitis in clinical practice. Journal of Periodontology 71(2): 156-163

Macmillan, M.L.; Radloff, G.A.; Defor, T.E.; Weisdorf, D.J.; Davies, S.M. 2003: Interleukin-1 genotype and outcome of unrelated donor bone marrow transplantation. British Journal of Haematology 121(4): 597-604

Tringali, G.; Dello Russo, C.; Preziosi, P.; Navarra, P. 2000: Interleukin-1 in the central nervous system: from physiology to pathology. Therapie 55(1): 171-175

Griffin, W.Sue.T.; Mrak, R.E. 2002: Interleukin-1 in the genesis and progression of and risk for development of neuronal degeneration in Alzheimer's disease. Journal of Leukocyte Biology 72(2): 233-238

Hickery, M.S.; Bayliss, M.T. 1998: Interleukin-1 induced nitric oxide inhibits sulphation of glycosaminoglycan chains in human articular chondrocytes. Biochimica et Biophysica Acta 1425(2): 282-290

Murray, C.A.; Clements, M.P.; Lynch, M.A. 1999: Interleukin-1 induces lipid peroxidation and membrane changes in rat hippocampus: An age-related study. Gerontology 45(3): 136-142

Johnson, K.; Hashimoto, S.; Lotz, M.; Pritzker, K.; Terkeltaub, R. 2001: Interleukin-1 induces pro-mineralizing activity of cartilage tissue transglutaminase and factor XIIIa. American Journal of Pathology 159(1): 149-163

Tanji, K.; Mori, F.; Imaizumi, T.; Yoshida, H.; Satoh, K.; Wakabayashi, K. 2003: Interleukin-1 induces tau phosphorylation and morphological changes in cultured human astrocytes. Neuroreport 14(3): 413-417

Komine, M.; Rao, L.S.; Freedberg, I.M.; Simon, M.; Milisavljevic, V.; Blumenberg, M. 2001: Interleukin-1 induces transcription of keratin K6 in human epidermal keratinocytes. Journal of Investigative Dermatology 116(2): 330-338

Mengshol, J.A.; Vincenti, M.P.; Coon, C.I.; Barchowsky, A.; Brinckerhoff, C.E. 2000: Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3. Arthritis and Rheumatism 43(4): 801-811

Touzani, O.; Boutin, H.; LeFeuvre, R.; Parker, L.; Miller, A.; Luheshi, G.; Rothwell, N. 2002: Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type i receptor. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 22(1): 38-43

Rölz, W.; Xin, C.; Ren, S.; Pfeilschifter, J.; Huwiler, A. 2002: Interleukin-1 inhibits angiotensin II-stimulated protein kinase B pathway in renal mesangial cells via the inducible nitric oxide synthase. European Journal of Pharmacology 442(3): 195-203

Däubener, W.; Hucke, C.; Seidel, K.; Hadding, U.; MacKenzie, C.R. 1999: Interleukin-1 inhibits gamma interferon-induced bacteriostasis in human uroepithelial cells. Infection and Immunity 67(11): 5615-5620

Zhu, H.; Liu, C. 2003: Interleukin-1 inhibits hepatitis C virus subgenomic RNA replication by activation of extracellular regulated kinase pathway. Journal of Virology 77(9): 5493-5498

Spandorfer, S.D.; Neuer, A.; Liu, H.C.; Bivis, L.; Clarke, R.; Veeck, L.; Witkin, S.S.; Rosenwaks, Z. 2000: Interleukin-1 levels in the supernatant of conditioned media of Embryos grown in autologous endometrial coculture: Correlation with outcome after in vitro fertilization. American Journal of Reproductive Immunology 43(1): 6-11

Li, Y.; Liu, L.; Barger, S.W.; Griffin, W.Sue.T. 2003: Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 23(5): 1605-1611

Takii, T.; Abe, C.; Tamura, A.; Ramayah, S.; Belisle, J.T.; Brennan, P.J.; Onozaki, K. 2001: Interleukin-1 or tumor necrosis factor-alpha augmented the cytotoxic effect of mycobacteria on human fibroblasts: application to evaluation of pathogenesis of clinical isolates of Mycobacterium tuberculosis and M. avium complex. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 21(3): 187-196

Thomas, H.E.; Darwiche, R.; Corbett, J.A.; Kay, T.W.H. 2002: Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production. Diabetes 51(2): 311-316

Obermeier, F.; Gross, V.; Schölmerich, J.; Falk, W. 1999: Interleukin-1 production by mouse macrophages is regulated in a feedback fashion by nitric oxide. Journal of Leukocyte Biology 66(5): 829-836

Sheng, J.G.; Zhu, S.G.; Jones, R.A.; Griffin, W.S.; Mrak, R.E. 2000: Interleukin-1 promotes expression and phosphorylation of neurofilament and tau proteins in vivo. Experimental Neurology 163(2): 388-391

Sheng, J.G.; Jones, R.A.; Zhou, X.Q.; McGinness, J.M.; Van Eldik, L.J.; Mrak, R.E.; Griffin, W.S. 2001: Interleukin-1 promotion of MAPK-p38 overexpression in experimental animals and in Alzheimer's disease: Potential significance for tau protein phosphorylation. Neurochemistry International 39(5-6): 341-348

Kothny-Wilkes, G.; Kulms, D.; Pöppelmann, B.; Luger, T.A.; Kubin, M.; Schwarz, T. 1998: Interleukin-1 protects transformed keratinocytes from tumor necrosis factor-related apoptosis-inducing ligand. Journal of Biological Chemistry 273(44): 29247-29253

Kothny-Wilkes, G.; Kulms, D.; Luger, T.A.; Kubin, M.; Schwarz, T. 1999: Interleukin-1 protects transformed keratinocytes from tumor necrosis factor-related apoptosis-inducing ligand- and CD95-induced apoptosis but not from ultraviolet radiation-induced apoptosis. Journal of Biological Chemistry 274(41): 28916-28921

Barahmani, N.; Barahamani, N.; de Andrade, M.; Slusser, J.; Zhang, Q.; Duvic, M. 2002: Interleukin-1 receptor antagonist allele 2 and familial alopecia areata. Journal of Investigative Dermatology 118(2): 335-337

Belperio, J.A.; DiGiovine, B.; Keane, M.P.; Burdick, M.D.; Ying Xue, Y.; Ross, D.J.; Lynch, J.P.; Kunkel, S.L.; Strieter, R.M. 2002: Interleukin-1 receptor antagonist as a biomarker for bronchiolitis obliterans syndrome in lung transplant recipients. Transplantation 73(4): 591-599

Corley, P.A. 2000: Interleukin-1 receptor antagonist as a treatment of HIV infection. Medical Hypotheses 54(4): 513-518

Sanderson, K.L.; Raghupathi, R.; Saatman, K.E.; Martin, D.; Miller, G.; McIntosh, T.K. 1999: Interleukin-1 receptor antagonist attenuates regional neuronal cell death and cognitive dysfunction after experimental brain injury. Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism 19(10): 1118-1125

Maish, G.O.; Shumate, M.L.; Ehrlich, H.P.; Vary, T.C.; Cooney, R.N. 1999: Interleukin-1 receptor antagonist attenuates tumor necrosis factor-induced alterations in wound breaking strength. Journal of Trauma 47(3): 533-537

Loscher, C.E.; Mills, K.H.G.; Lynch, M.A. 2003: Interleukin-1 receptor antagonist exerts agonist activity in the hippocampus independent of the interleukin-1 type I receptor. Journal of Neuroimmunology 137(1-2): 117-124

Dewberry, R.; Holden, H.; Crossman, D.; Francis, S. 2000: Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology 20(11): 2394-2400

Witkin, S.S.; Linhares, I.M.; Gerber, S.; Caetano, M.E.; Segurado, A.C. 2001: Interleukin-1 receptor antagonist gene polymorphism and circulating levels of human immunodeficiency virus type 1 RNA in Brazilian women. Journal of Virology 75(13): 6242-6244

Francis, S.E.; Camp, N.J.; Dewberry, R.M.; Gunn, J.; Syrris, P.; Carter, N.D.; Jeffery, S.; Kaski, J.C.; Cumberland, D.C.; Duff, G.W.; Crossman, D.C. 1999: Interleukin-1 receptor antagonist gene polymorphism and coronary artery disease. Circulation 99(7): 861-866

Arnalich, F.; López-Maderuelo, D.; Codoceo, R.; Lopez, J.; Solis-Garrido, L.M.; Capiscol, C.; Fernandez-Capitán, C.; Madero, R.; Montiel, C. 2002: Interleukin-1 receptor antagonist gene polymorphism and mortality in patients with severe sepsis. Clinical and Experimental Immunology 127(2): 331-336

Worrall, B.B.; Azhar, S.; Nyquist, P.A.; Ackerman, R.H.; Hamm, T.L.; DeGraba, T.J. 2003: Interleukin-1 receptor antagonist gene polymorphisms in carotid atherosclerosis. Stroke 34(3): 790-793

Marculescu, R.; Endler, G.; Schillinger, M.; Iordanova, N.; Exner, M.; Hayden, E.; Huber, K.; Wagner, O.; Mannhalter, C. 2002: Interleukin-1 receptor antagonist genotype is associated with coronary atherosclerosis in patients with type 2 diabetes. Diabetes 51(12): 3582-3585

Schwarz, Y.A.; Amin, R.S.; Stark, J.M.; Trapnell, B.C.; Wilmott, R.W. 1999: Interleukin-1 receptor antagonist inhibits interleukin-8 expression in A549 respiratory epithelial cells infected in vitro with a replication-deficient recombinant adenovirus vector. American Journal of Respiratory Cell and Molecular Biology 21(3): 388-394

Ueland, T.; Kristo, C.; Godang, K.; Aukrust, P.; Bollerslev, J. 2003: Interleukin-1 receptor antagonist is associated with fat distribution in endogenous Cushing's syndrome: a longitudinal study. Journal of Clinical Endocrinology and Metabolism 88(4): 1492-1496

Gottsäter, A.; Forsblad, J.; Mätzsch, T.; Persson, K.; Ljungcrantz, I.; Ohlsson, K.; Lindgärde, F. 2002: Interleukin-1 receptor antagonist is detectable in human carotid artery plaques and is related to triglyceride levels and Chlamydia pneumoniae IgA antibodies. Journal of Internal Medicine 251(1): 61-68

IIzuka, N.; Hazama, S.; Hirose, K.; Abe, T.; Tokuda, N.; Fukumoto, T.; Tangoku, A.; Oka, M. 1999: Interleukin-1 receptor antagonist mRNA expression and the progression of gastric carcinoma. Cancer Letters 142(2): 179-184

Simón, C.; Valbuena, D.; Krüssel, J.; Bernal, A.; Murphy, C.R.; Shaw, T.; Pellicer, A.; Polan, M.L. 1998: Interleukin-1 receptor antagonist prevents embryonic implantation by a direct effect on the endometrial epithelium. Fertility and Sterility 70(5): 896-906

Mühlberg, T.; Joba, W.; Spitzweg, C.; Schworm, H.D.; Heberling, H.J.; Heufelder, A.E. 2000: Interleukin-1 receptor antagonist ribonucleic acid and protein expression by cultured Graves' and normal orbital fibroblasts is differentially modulated by dexamethasone and irradiation. Journal of Clinical Endocrinology and Metabolism 85(2): 734-742

Balakrishnan, V.S.; Jaber, B.L.; Natov, S.N.; Cendoroglo, M.; King, A.J.; Schmid, C.H.; Pereira, B.J. 1998: Interleukin-1 receptor antagonist synthesis by peripheral blood mononuclear cells in hemodialysis patients. Kidney International 54(6): 2106-2112

Balakrishnan, V.S.; Schmid, C.H.; Jaber, B.L.; Natov, S.N.; King, A.J.; Pereira, B.J.G. 2000: Interleukin-1 receptor antagonist synthesis by peripheral blood mononuclear cells: a novel predictor of morbidity among hemodialysis patients. Journal of the American Society of Nephrology: Jasn 11(11): 2114-2121

Yamada, J.; Zhu, S.N.; Streilein, J.W.; Dana, M.R. 2000: Interleukin-1 receptor antagonist therapy and induction of anterior chamber-associated immune deviation-type tolerance after corneal transplantation. IOVS Investigative Ophthalmology and Visual Science 41(13): 4203-4208

Perini, P.; Tiberio, M.; Sivieri, S.; Facchinetti, A.; Biasi, G.; Gallo, P. 2000: Interleukin-1 receptor antagonist, soluble tumor necrosis factor-a receptor type I and II and soluble E-selectin serum levels in multiple sclerosis patients receiving weekly intramuscular injections of interferon-beta1a. European Cytokine Network 11(1): 81-85

Guo-Fukun; Li-Yilei; Wu-Shuguang 2000: Interleukin-1 receptor associated kinase-1 and -2 synergetically activate NF-kappaB. Zhonghua Weishengwuxue He Mianyixue Zazhi 20(4): 340-343

Dale, M.; Nicklin, M.J. 1999: Interleukin-1 receptor cluster: gene organization of IL1R2, IL1R1, IL1RL2 (IL-1Rrp2), IL1RL1 (T1/ST2), and IL18R1 (IL-1Rrp) on human chromosome 2q. Genomics 57(1): 177-179

Morris, J.L.; Jobling, P.; Shimizu, T.; Gibbins, I.L. 2002: Interleukin-1 receptor immunoreactivity in sympathetic vascular and non-vascular neurons in guinea-pig coeliac ganglion. Neuroscience Letters 333(1): 54-58

Graves, D.T.; Chen, C.P.; Douville, C.; Jiang, Y. 2000: Interleukin-1 receptor signaling rather than that of tumor necrosis factor is critical in protecting the host from the severe consequences of a polymicrobe anaerobic infection. Infection and Immunity 68(8): 4746-4751

Sewnath, M.E.; Van Der Poll, T.; Ten Kate, F.J.W.; Van Noorden, C.J.F.; Gouma, D.J. 2002: Interleukin-1 receptor type i gene-deficient bile duct-ligated mice are partially protected against endotoxin. Hepatology 35(1): 149-158

Boelens, J.J.; van der Poll, T.; Zaat, S.A.; Murk, J.L.; Weening, J.J.; Dankert, J. 2000: Interleukin-1 receptor type i gene-deficient mice are less susceptible to Staphylococcus epidermidis biomaterial-associated infection than are wild-type mice. Infection and Immunity 68(12): 6924-6931

Greene, C.; O'Neill, L. 1999: Interleukin-1 receptor-associated kinase and TRAF-6 mediate the transcriptional regulation of interleukin-2 by interleukin-1 via NFkappaB but unlike interleukin-1 are unable to stabilise interleukin-2 mRNA. Biochimica et Biophysica Acta 1451(1): 109-121

Sobue, T.; Zhang, X.; Florkiewicz, R.Z.; Hurley, M.M. 2001: Interleukin-1 regulates FGF-2 mRNA and localization of FGF-2 protein in human osteoblasts. Biochemical and Biophysical Research Communications 286(1): 33-40

Vela, Jé.M.; Molina-Holgado, E.; Arévalo-Martín, A.; Almazán, G.; Guaza, C. 2002: Interleukin-1 regulates proliferation and differentiation of oligodendrocyte progenitor cells. Molecular and Cellular Neurosciences 20(3): 489-502

Böl, G.F.; Tewes, F.; Brigelius-Flohé, R. 1999: Interleukin-1 signaling is dependent on free thiols. Biofactors 10(2-3): 175-178

Juffermans, N.P.; Florquin, S.; Camoglio, L.; Verbon, A.; Kolk, A.H.; Speelman, P.; van Deventer, S.J.; van Der Poll, T. 2000: Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis. Journal of Infectious Diseases 182(3): 902-908

Huang, S.; Konieczkowski, M.; Schelling, J.R.; Sedor, J.R. 1999: Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells. Kidney International 55(5): 1740-1749

Rauk, P.N.; Chiao, J.P. 2000: Interleukin-1 stimulates human uterine prostaglandin production through induction of cyclooxygenase-2 expression. American Journal of Reproductive Immunology 43(3): 152-159

Singer, C.F.; Kronsteiner, N.; Marton, E.; Walter, I.; Kubista, M.; Czerwenka, K.; Schreiber, M.; Tschugguel, W.; Wieser, F.; Kubista, E. 2002: Interleukin-1 system and sex steroid receptor gene expression in human endometrial cancer. Gynecologic Oncology 85(3): 423-430

Constantini, P.K.; Wawrzynowicz-Syczewska, M.; Clare, M.; Boron-Kaczmarska, A.; McFarlane, I.G.; Cramp, M.E.; Donaldson, P.T. 2002: Interleukin-1, interleukin-10 and tumour necrosis factor-alpha gene polymorphisms in hepatitis C virus infection: An investigation of the relationships with spontaneous viral clearance and response to alpha-interferon therapy. Liver 22(5): 404-412

Mrak, R.E.; Griffin, W.S.e T. 2001: Interleukin-1, neuroinflammation, and Alzheimer's disease. Neurobiology of Aging 22(6): 903-908

Gotoh, M.; Hamada, K.; Yamakawa, H.; Yanagisawa, K.; Nakamura, M.; Yamazaki, H.; Inoue, A.; Fukuda, H. 2002: Interleukin-1-induced glenohumeral synovitis and shoulder pain in rotator cuff diseases. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society 20(6): 1365-1371

Han, Y.; Meng, T.; Murray, N.R.; Fields, A.P.; Brasier, A.R. 1999: Interleukin-1-induced nuclear factor-kappaB-IkappaBalpha autoregulatory feedback loop in hepatocytes. A role for protein kinase calpha in post-transcriptional regulation of ikappabalpha resynthesis. Journal of Biological Chemistry 274(2): 939-947

Gotoh, M.; Hamada, K.; Yamakawa, H.; Yanagisawa, K.; Nakamura, M.; Yamazaki, H.; Ueyama, Y.; Tamaoki, N.; Inoue, A.; Fukuda, H. 2001: Interleukin-1-induced subacromial synovitis and shoulder pain in rotator cuff diseases. Rheumatology 40(9): 995-1001

Randolph-Habecker, J.; Iwata, M.; Geballe, A.P.; Jarrahian, S.; Torok-Storb, B. 2002: Interleukin-1-mediated inhibition of cytomegalovirus replication is due to increased IFN-beta production. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 22(7): 765-772

Tebo, J.M.; Datta, S.; Kishore, R.; Kolosov, M.; Major, J.A.; Ohmori, Y.; Hamilton, T.A. 2000: Interleukin-1-mediated stabilization of mouse KC mRNA depends on sequences in both 5'- and 3'-untranslated regions. Journal of Biological Chemistry 275(17): 12987-12993

Steude, J.; Kulke, R.; Christophers, E. 2002: Interleukin-1-stimulated secretion of interleukin-8 and growth-related oncogene-alpha demonstrates greatly enhanced keratinocyte growth in human raft cultured epidermis. Journal of Investigative Dermatology 119(6): 1254-1260

Daun, J.M.; Fenton, M.J. 2000: Interleukin-1/Toll receptor family members: receptor structure and signal transduction pathways. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 20(10): 843-855

Furukawa, Y.; Becker, G.; Stinn, J.L.; Shimizu, K.; Libby, P.; Mitchell, R.N. 1999: Interleukin-10 (IL-10) augments allograft arterial disease: paradoxical effects of IL-10 in vivo. American Journal of Pathology 155(6): 1929-1939

Tagore, A.; Gonsalkorale, W.M.; Pravica, V.; Hajeer, A.H.; Mcmahon, R.; Whorwell, P.J.; Sinnott, P.J.; Hutchinson, I.V. 1999: Interleukin-10 (IL-10) genotypes in inflammatory bowel disease. Tissue Antigens 54(4): 386-390

Cassatella, M.A.; Gasperini, S.; Bovolenta, C.; Calzetti, F.; Vollebregt, M.; Scapini, P.; Marchi, M.; Suzuki, R.; Suzuki, A.; Yoshimura, A. 1999: Interleukin-10 (IL-10) selectively enhances CIS3/SOCS3 mRNA expression in human neutrophils: evidence for an IL-10-induced pathway that is independent of STAT protein activation. Blood 94(8): 2880-2889

Girndt, M.; Kohler, H. 2003: Interleukin-10 (IL-10): an update on its relevance for cardiovascular risk. Nephrology Dialysis Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association 18(10): 1976-1979

Pickard, C.; Mann, C.; Sinnott, P.; Boggild, M.; Hawkins, C.; Strange, R.C.; Hutchinson, I.V.; Ollier, W.E.; Donn, R.P. 1999: Interleukin-10 (IL10) promoter polymorphisms and multiple sclerosis. Journal of Neuroimmunology 101(2): 207-210

Bejarano, M.T.; Masucci, M.G. 1998: Interleukin-10 abrogates the inhibition of Epstein-Barr virus-induced B-cell transformation by memory T-cell responses. Blood 92(11): 4256-4262

Ripley, B.J.; Stephanou, A.; Isenberg, D.A.; Latchman, D.S. 1999: Interleukin-10 activates heat-shock protein 90beta gene expression. Immunology 97(2): 226-231

Robb, B.W.; Hershko, D.D.; Paxton, J.H.; Luo, G-Ju.; Hasselgren, P-Olof. 2002: Interleukin-10 activates the transcription factor C/EBP and the interleukin-6 gene promoter in human intestinal epithelial cells. Surgery 132(2): 226-231

Stearns, M.E.; Wang, M.; Hu, Y.; Garcia, F.U. 2003: Interleukin-10 activation of the interleukin-10E1 pathway and tissue inhibitor of metalloproteinase-1 expression is enhanced by proteasome inhibitors in primary prostate tumor lines. Molecular Cancer Research: Mcr 1(9): 631-642

Terrone, D.A.; Rinehart, B.K.; Granger, J.P.; Barrilleaux, P.S.; Martin, J.N.; Bennett, W.A. 2001: Interleukin-10 administration and bacterial endotoxin-induced preterm birth in a rat model. Obstetrics and Gynecology 98(3): 476-480

Gjertsson, I.; Hultgren, O.H.; Tarkowski, A. 2002: Interleukin-10 ameliorates the outcome of Staphylococcus aureus arthritis by promoting bacterial clearance. Clinical and Experimental Immunology 130(3): 409-414

Delogu, G.; Famularo, G.; Moretti, S.; De Luca, A.; Tellan, G.; Antonucci, A.; Marandola, M.; Signore, L. 2001: Interleukin-10 and apoptotic death of circulating lymphocytes in surgical/anesthesia trauma. Journal of Trauma 51(1): 92-97

Gasperini, S.; Crepaldi, L.; Calzetti, F.; Gatto, L.; Berlato, C.; Bazzoni, F.; Yoshimura, A.; Cassatella, M.A. 2002: Interleukin-10 and cAMP-elevating agents cooperate to induce suppressor of cytokine signaling-3 via a protein kinase A-independent signal. European Cytokine Network 13(1): 47-53

Pahan, K.; Khan, M.; Singh, I. 2000: Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase. Journal of Neurochemistry 75(2): 576-582

Birkeland, S.A.; Bendtzen, K.; Møller, B.; Hamilton-Dutoit, S.; Andersen, H.K. 1999: Interleukin-10 and posttransplant lymphoproliferative disorder after kidney transplantation. Transplantation 67(6): 876-881

Haddad, J.J.; Saadé, N.E.; Safieh-Garabedian, B. 2003: Interleukin-10 and the regulation of mitogen-activated protein kinases: Are these signalling modules targets for the anti-inflammatory action of this cytokine?. Cellular Signalling 15(3): 255-267

Hobbs, K.; Negri, J.; Klinnert, M.; Rosenwasser, L.J.; Borish, L. 1998: Interleukin-10 and transforming growth factor-beta promoter polymorphisms in allergies and asthma. American Journal of Respiratory and Critical Care Medicine 158(6): 1958-1962

Koch, W.; Kastrati, A.; Böttiger, C.; Mehilli, J.; von Beckerath, N.; Schömig, A. 2001: Interleukin-10 and tumor necrosis factor gene polymorphisms and risk of coronary artery disease and myocardial infarction. Atherosclerosis 159(1): 137-144

Kastin, A.J.; Akerstrom, V.; Pan, W. 2003: Interleukin-10 as a CNS therapeutic: The obstacle of the blood-brain/blood-spinal cord barrier. Brain Research. Molecular Brain Research 114(2): 168-171

Huizinga, T.W.; van der Linden, M.W.; Deneys-Laporte, V.; Breedveld, F.C. 1999: Interleukin-10 as an explanation for pregnancy-induced flare in systemic lupus erythematosus and remission in rheumatoid arthritis. Rheumatology 38(6): 496-498

Lauwerys, B.R.; Garot, N.; Renauld, J.C.; Houssiau, F.A. 2000: Interleukin-10 blockade corrects impaired in vitro cellular immune responses of systemic lupus erythematosus patients. Arthritis and Rheumatism 43(9): 1976-1981

Pinderski Oslund, L.J.; Hedrick, C.C.; Olvera, T.; Hagenbaugh, A.; Territo, M.; Berliner, J.A.; Fyfe, A.I. 1999: Interleukin-10 blocks atherosclerotic events in vitro and in vivo. Arteriosclerosis Thrombosis and Vascular Biology 19(12): 2847-2853

Mochida-Nishimura, K.; Akagawa, K.S.; Rich, E.A. 2001: Interleukin-10 contributes development of macrophage suppressor activities by macrophage colony-stimulating factor, but not by granulocyte-macrophage colony-stimulating factor. Cellular Immunology 214(1): 81-88

Louis, H.; Van Laethem, J.L.; Wu, W.; Quertinmont, E.; Degraef, C.; Van den Berg, K.; Demols, A.; Goldman, M.; Le Moine, O.; Geerts, A.; Devière, J. 1998: Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice. Hepatology 28(6): 1607-1615

Latifi, S.Q.; O'Riordan, M.A.; Levine, A.D. 2002: Interleukin-10 controls the onset of irreversible septic shock. Infection and Immunity 70(8): 4441-4446

Ikeda, T.; Sato, K.; Kuwada, N.; Matsumura, T.; Yamashita, T.; Kimura, F.; Hatake, K.; Ikeda, K.; Motoyoshi, K. 2002: Interleukin-10 differently regulates monocyte chemoattractant protein-1 gene expression depending on the environment in a human monoblastic cell line, UG3. Journal of Leukocyte Biology 72(6): 1198-1205

Faulkner, L.; Buchan, G.; Baird, M. 2000: Interleukin-10 does not affect phagocytosis of particulate antigen by bone marrow-derived dendritic cells but does impair antigen presentation. Immunology 99(4): 523-531

Seldon, P.M.; Barnes, P.J.; Giembycz, M.A. 1998: Interleukin-10 does not mediate the inhibitory effect of PDE-4 inhibitors and other cAMP-elevating drugs on lipopolysaccharide-induced tumors necrosis factor-alpha generation from human peripheral blood monocytes. Cell Biochemistry and Biophysics 29(1-2): 179-201

Blazar, B.R.; Taylor, P.A.; Panoskaltsis-Mortari, A.; Narula, S.K.; Smith, S.R.; Roncarolo, M.G.; Vallera, D.A. 1998: Interleukin-10 dose-dependent regulation of CD4+ and CD8+ T cell-mediated graft-versus-host disease. Transplantation 66(9): 1220-1229

Luo, W.; Fine, J.; Garg, M.; Kaplan, A.M.; Bondada, S. 1999: Interleukin-10 enhances immune responses to pneumococcal polysaccharides and sheep erythrocytes in young and aged mice. Cellular Immunology 195(1): 1-9

Kaufman, H.L.; Rao, J.B.; Irvine, K.R.; Bronte, V.; Rosenberg, S.A.; Restifo, N.P.; Irivine, K.R. 1999: Interleukin-10 enhances the therapeutic effectiveness of a recombinant poxvirus-based vaccine in an experimental murine tumor model. Journal of ImmunoTherapy 22(6): 489-496

Rabbi, M.F.; Finnegan, A.; Al-Harthi, L.; Song, S.; Roebuck, K.A. 1998: Interleukin-10 enhances tumor necrosis factor-alpha activation of HIV-1 transcription in latently infected T cells. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology: Official Publication of the International Retrovirology Association 19(4): 321-331

Seo, N.; Hayakawa, S.; Takigawa, M.; Tokura, Y. 2001: Interleukin-10 expressed at early tumour sites induces subsequent generation of CD4(+) T-regulatory cells and systemic collapse of antitumour immunity. Immunology 103(4): 449-457

Deleuze, V.; Scherman, D.; Bureau, M.F. 2002: Interleukin-10 expression after intramuscular DNA electrotransfer: Kinetic studies. Biochemical and Biophysical Research Communications 299(1): 29-34

Thompson, K.; Maltby, J.; Fallowfield, J.; McAulay, M.; Millward-Sadler, H.; Sheron, N. 1998: Interleukin-10 expression and function in experimental murine liver inflammation and fibrosis. Hepatology 28(6): 1597-1606

Akagi, S.; Hiyama, E.; Imamura, Y.; Takesue, Y.; Matsuura, Y.; Yokoyama, T. 2000: Interleukin-10 expression in intestine of Crohn disease. International Journal of Molecular Medicine 5(4): 389-395

Kamiya, T.; Hatanaka, H.; Abe, Y.; Kijima, H.; Yamazaki, H.; Ohnishi, Y.; Inoue, H.; Ueyama, Y.; Osamura, Y.; Nakamura, M. 2003: Interleukin-10 expression is closely correlated with the expression of granulocyte-macrophage colony-stimulating factor in non-small cell lung cancer. Anticancer Research 23(3c): 2909-2913

Naruke, M.; Abe, Y.; Hatanaka, H.; Ohnishi, Y.; Yamazaki, H.; Kijima, H.; Nakamura, M.; Ueyama, Y.; Kobayashi, K. 2001: Interleukin-10 expression is correlated with growth fraction in human non-small cell lung cancer xenografts. International Journal of Oncology 18(6): 1213-1217

Rectenwald, J.E.; Minter, R.M.; Moldawer, L.L.; Abouhamze, Z.; La Face, D.; Hutchins, E.; Huber, T.S.; Seeger, J.M.; Ozaki, C.K. 2002: Interleukin-10 fails to modulate low shear stress-induced neointimal hyperplasia. Journal of Surgical Research 102(2): 110-118

Zheng, C.; Huang, D.; Liu, L.; Wu, R.; Bergenbrant Glas, S.; Osterborg, A.; Björkholm, M.; Holm, G.; Yi, Q.; Sundblad, A. 2001: Interleukin-10 gene promoter polymorphisms in multiple myeloma. International Journal of Cancer 95(3): 184-188

Karjalainen, J.; Hulkkonen, J.; Nieminen, M.M.; Huhtala, H.; Aromaa, A.; Klaukka, T.; Hurme, M. 2003: Interleukin-10 gene promoter region polymorphism is associated with eosinophil count and circulating Immunoglobulin E in adult asthma. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology 33(1): 78-83

Morrison, D.F.; Foss, D.L.; Murtaugh, M.P. 2000: Interleukin-10 gene therapy-mediated amelioration of bacterial pneumonia. Infection and Immunity 68(8): 4752-4758

Sun, H.; Jackson, M.J.; Kundu, N.; Fulton, A.M. 1999: Interleukin-10 gene transfer activates interferon-gamma and the interferon-gamma-inducible genes Gbp-1/Mag-1 and Mig-1 in mammary tumors. International Journal of Cancer 80(4): 624-629

Stämpfli, M.R.; Cwiartka, M.; Gajewska, B.U.; Alvarez, D.; Ritz, S.A.; Inman, M.D.; Xing, Z.; Jordana, M. 1999: Interleukin-10 gene transfer to the airway regulates allergic mucosal sensitization in mice. American Journal of Respiratory Cell and Molecular Biology 21(5): 586-596

Wu, M.-S.; Wu, C.-Y.; Chen, C.-J.; Lin, M.-T.; Shun, C.-T.; Lin, J.-T. 2003: Interleukin-10 genotypes associate with the risk of gastric carcinoma in Taiwanese Chinese. International Journal of Cancer 104(5): 617-623

Samsom, J.N.; Annema, A.; Geertsma, M.F.; Langermans, J.A.; Groeneveld, P.H.; de Heer, E.; van Furth, R. 2000: Interleukin-10 has different effects on proliferation of Listeria monocytogenes in livers and spleens of mice. Infection and Immunity 68(8): 4666-4672

Zidek, Z.; Franková, D. 1999: Interleukin-10 in combination with interferon-gamma and tumor necrosis factor-alpha enhances in vitro production of nitric oxide by murine resident paritoneal macrophage. European Cytokine Network 10(1): 25-32

Berger, S.; Siegert, A.; Denkert, C.; Köbel, M.; Hauptmann, S. 2001: Interleukin-10 in serous ovarian carcinoma cell lines. Cancer Immunology Immunotherapy: Cii 50(6): 328-333

Santin, A.D.; Hermonat, P.L.; Ravaggi, A.; Bellone, S.; Pecorelli, S.; Roman, J.J.; Parham, G.P.; Cannon, M.J. 2000: Interleukin-10 increases Th1 cytokine production and cytotoxic potential in human papillomavirus-specific CD8(+) cytotoxic T lymphocytes. Journal of Virology 74(10): 4729-4737

Wang, Z.Q.; Bapat, A.S.; Rayanade, R.J.; Dagtas, A.S.; Hoffmann, M.K. 2001: Interleukin-10 induces macrophage apoptosis and expression of CD16 (FcgammaRIII) whose engagement blocks the cell death programme and facilitates differentiation. Immunology 102(3): 331-337

Vlad, G.; Piazza, F.; Colovai, A.; Cortesini, R.; Della Pietra, F.; Suciu-Foca, N.; Manavalan, J.S. 2003: Interleukin-10 induces the upregulation of the inhibitory receptor ILT4 in monocytes from HIV positive individuals. Human Immunology 64(5): 483-489

Arany, I.; Grattendick, K.G.; Tyring, S.K. 2002: Interleukin-10 induces transcription of the early promoter of human papillomavirus type 16 (HPV16) through the 5'-segment of the upstream regulatory region (URR). Antiviral Research 55(2): 331-339

Cattaruzza, M.; Słodowski, W.; Stojakovic, M.; Krzesz, R.; Hecker, M. 2003: Interleukin-10 induction of nitric-oxide synthase expression attenuates CD40-mediated interleukin-12 synthesis in human endothelial cells. Journal of Biological Chemistry 278(39): 37874-37880

Kumar, A.; Steinkasserer, A.; Berchtold, S. 2003: Interleukin-10 influences the expression of MRP8 and MRP14 in human dendritic cells. International Archives of Allergy and Immunology 132(1): 40-47

Fortunato, S.J.; Menon, R.; Lombardi, S.J.; Lafleur, B. 2001: Interleukin-10 inhibition of gelatinases in fetal membranes: Therapeutic implications in preterm premature rupture of membranes. Obstetrics and Gynecology 98(2): 284-288

Huang, C.-J.; Stevens, B.R.; Nielsen, R.B.; Slovin, P.N.; Fang, X.; Nelson, D.R.; Skimming, J.W. 2002: Interleukin-10 inhibition of nitric oxide biosynthesis involves suppression of CAT-2 transcription. Nitric Oxide: Biology and Chemistry 6(1): 79-84

Sawada, M.; Suzumura, A.; Hosoya, H.; Marunouchi, T.; Nagatsu, T. 1999: Interleukin-10 inhibits both production of cytokines and expression of cytokine receptors in microglia. Journal of Neurochemistry 72(4): 1466-1471

Oehler, L.; Kollars, M.; Bohle, B.; Berer, A.; Reiter, E.; Lechner, K.; Geissler, K. 1999: Interleukin-10 inhibits burst-forming unit-erythroid growth by suppression of endogenous granulocyte-macrophage colony-stimulating factor production from T cells. Experimental Hematology 27(2): 217-223

Pollice, P.F.; Hsu, J.; Hicks, D.G.; Bukata, S.; Rosier, R.N.; Reynolds, P.R.; Puzas, J.E.; O'Keefe, R.J. 1998: Interleukin-10 inhibits cytokine synthesis in monocytes stimulated by titanium particles: evidence of an anti-inflammatory regulatory pathway. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society 16(6): 697-704

Kitching, A.R.; Katerelos, M.; Mudge, S.J.; Tipping, P.G.; Power, D.A.; Holdsworth, S.R. 2002: Interleukin-10 inhibits experimental mesangial proliferative glomerulonephritis. Clinical and Experimental Immunology 128(1): 36-43

Nagaki, M.; Tanaka, M.; Sugiyama, A.; Ohnishi, H.; Moriwaki, H. 1999: Interleukin-10 inhibits hepatic injury and tumor necrosis factor-alpha and interferon-gamma mRNA expression induced by staphylococcal enterotoxin B or lipopolysaccharide in galactosamine-sensitized mice. Journal of Hepatology 31(5): 815-824

Feldman, L.J.; Aguirre, L.; Ziol, M.; Bridou, J.P.; Nevo, N.; Michel, J.B.; Steg, P.G. 2000: Interleukin-10 inhibits intimal hyperplasia after angioplasty or stent implantation in hypercholesterolemic rabbits. Circulation 101(8): 908-916

Deng, J.; Kohda, Y.; Chiao, H.; Wang, Y.; Hu, X.; Hewitt, S.M.; Miyaji, T.; McLeroy, P.; Nibhanupudy, B.; Li, S.; Star, R.A. 2001: Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury. Kidney International 60(6): 2118-2128

Huang, X.R.; Kitching, A.R.; Tipping, P.G.; Holdsworth, S.R. 2000: Interleukin-10 inhibits macrophage-induced glomerular injury. Journal of the American Society of Nephrology: Jasn 11(2): 262-269

Trindade, M.C.; Lind, M.; Nakashima, Y.; Sun, D.; Goodman, S.B.; Schurman, D.J.; Smith, R.L. 2001: Interleukin-10 inhibits polymethylmethacrylate particle induced interleukin-6 and tumor necrosis factor-alpha release by human monocyte/macrophages in vitro. Biomaterials 22(15): 2067-2073

Selzman, C.H.; Meldrum, D.R.; Cain, B.S.; Meng, X.; Shames, B.D.; Ao, L.; Harken, A.H. 1998: Interleukin-10 inhibits postinjury tumor necrosis factor-mediated human vascular smooth muscle proliferation. Journal of Surgical Research 80(2): 352-356

Lisinski, T.J.; Furie, M.B. 2002: Interleukin-10 inhibits proinflammatory activation of endothelium in response to Borrelia burgdorferi or lipopolysaccharide but not interleukin-1beta or tumor necrosis factor alpha. Journal of Leukocyte Biology 72(3): 503-511

Yoshidome, H.; Kato, A.; Edwards, M.J.; Lentsch, A.B. 1999: Interleukin-10 inhibits pulmonary NF-kappaB activation and lung injury induced by hepatic ischemia-reperfusion. American Journal of Physiology 277(5): L919-L923

Kushikata, T.; Fang, J.; Krueger, J.M. 1999: Interleukin-10 inhibits spontaneous sleep in rabbits. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 19(9): 1025-1030

Takahashi, T.; Maeda, K.I.; Nakamura, Y.; Okano, Y.; Ge, N.; Sone, S. 2000: Interleukin-10 inhibits the production of inflammatory cytokines by antigen-stimulated mononuclear cells from asthmatic patients. Allergology International 49(1): 55-62

Vandebriel, R.J.; Meredith, C.; Scott, M.P.; Van Dijk, M.; Van Loveren, H. 2000: Interleukin-10 is an unequivocal Th2 parameter in the rat, whereas interleukin-4 is not. Scandinavian Journal of Immunology 52(5): 519-524

Ishizuka, T.; Okayama, Y.; Kobayashi, H.; Mori, M. 1999: Interleukin-10 is localized to and released by human lung mast cells. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology 29(10): 1424-1432

Takanashi, S.; Hasegawa, Y.; Kanehira, Y.; Yamamoto, K.; Fujimoto, K.; Satoh, K.; Okamura, K. 1999: Interleukin-10 level in sputum is reduced in bronchial asthma, COPD and in smokers. European Respiratory Journal 14(2): 309-314

Miller, L.J.; Fischer, K.A.; Goralnick, S.J.; Litt, M.; Burleson, J.A.; Albertsen, P.; Kreutzer, D.L. 2002: Interleukin-10 levels in seminal plasma: Implications for chronic prostatitis-chronic pelvic pain syndrome. Journal of Urology 167(2 Pt 1): 753-756

Pomini, F.; Caruso, A.; Challis, J.R. 1999: Interleukin-10 modifies the effects of interleukin-1beta and tumor necrosis factor-alpha on the activity and expression of prostaglandin H synthase-2 and the NAD+-dependent 15-hydroxyprostaglandin dehydrogenase in cultured term human villous trophoblast and chorion trophoblast cells. Journal of Clinical Endocrinology and Metabolism 84(12): 4645-4651

Grilli, M.; Barbieri, I.; Basudev, H.; Brusa, R.; Casati, C.; Lozza, G.; Ongini, E. 2000: Interleukin-10 modulates neuronal threshold of vulnerability to ischaemic damage. European Journal of Neuroscience 12(7): 2265-2272

Balabanian, K.; Foussat, A.; Bouchet-Delbos, L.; Couderc, J.; Krzysiek, R.; Amara, A.; Baleux, Fçoise.; Portier, A.; Galanaud, P.; Emilie, D. 2002: Interleukin-10 modulates the sensitivity of peritoneal B lymphocytes to chemokines with opposite effects on stromal cell-derived factor-1 and B-lymphocyte chemoattractant. Blood 99(2): 427-436

Wang, X-Nong.; Lange, C.; Schulz, U.; Sviland, L.; Eissner, Günther.; Oliver, K.M.; Jackson, G.H.; Holler, E.; Dickinson, A.M. 2002: Interleukin-10 modulation of alloreactivity and graft-versus-host reactions. Transplantation 74(6): 772-778

Zwijnenburg, P.J.G.; van der Poll, T.; Florquin, S.; Roord, J.J.; van Furth, A.Marceline. 2003: Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis. Infection and Immunity 71(4): 2276-2279

Martinez Doncel, A.; Rubio, A.; Arroyo, R.; de las Heras, V.; Martín, C.; Fernandez-Arquero, M.; de la Concha, E.G. 2002: Interleukin-10 polymorphisms in Spanish Multiple Sclerosis patients. Journal of Neuroimmunology 131(1-2): 168-172

Bachis, A.; Colangelo, A.M.; Vicini, S.; Doe, P.P.; De Bernardi, M.A.; Brooker, G.; Mocchetti, I. 2001: Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 21(9): 3104-3112

Tan, B.B.; Prewitt, R.L.; Britt, L.D. 2001: Interleukin-10 prevents loss of tone of rat skeletal muscle arterioles exposed to endotoxin. Journal of Surgical Research 100(1): 110-115

Hessle, C.; Hanson, L.A.; Wold, A.E. 2000: Interleukin-10 produced by the innate immune system masks in vitro evidence of acquired T-cell immunity to E. coli. Scandinavian Journal of Immunology 52(1): 13-20

Moraes, M.O.; Santos, A.R.; Schonkeren, J.J.M.; Vanderborght, Pícia.R.; Ottenhoff, T.H.M.; Moraes, M.E.; Moraes, Jé.R.; Sampaio, E.P.; Sarno, E.N.; Huizinga, T.W.J. 2003: Interleukin-10 promoter haplotypes are differently distributed in the Brazilian versus the Dutch population. Immunogenetics 54(12): 896-899

Hensen, P.; Asadullah, K.; Windemuth, C.; Rüschendorf, F.; Hüffmeier, U.; Ständer, M.; Schmitt-Egenolf, M.; Wienker, T.F.; Reis, A.; Traupe, H. 2003: Interleukin-10 promoter polymorphism IL10.G and familial early onset psoriasis. British Journal of Dermatology 149(2): 381-385

Almeras, L.; Meresse, B.; Seze, Jérôme.; De Lefranc, D.; Dubucquoi, S.; Fajardy, I.; Vermersch, P.; Prin, L. 2002: Interleukin-10 promoter polymorphism in multiple sclerosis: association with disease progression. European Cytokine Network 13(2): 200-206

Asadullah, K.; Eskdale, J.; Wiese, A.; Gallagher, G.; Friedrich, M.; Sterry, W. 2001: Interleukin-10 promoter polymorphism in psoriasis. Journal of Investigative Dermatology 116(6): 975-978

Edwards-Smith, C.J.; Jonsson, J.R.; Purdie, D.M.; Bansal, A.; Shorthouse, C.; Powell, E.E. 1999: Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon alfa. Hepatology 30(2): 526-530

Roh, J.Won.; Kim, M.Hong.; Seo, S.Soo.; Kim, S.Hyeong.; Kim, J.Weon.; Park, N.Hyun.; Song, Y.Sang.; Park, S.Yoon.; Kang, S.Beom.; Lee, H.Pyo. 2002: Interleukin-10 promoter polymorphisms and cervical cancer risk in Korean women. Cancer Letters 184(1): 57-63

Myhr, K-M.; Vågnes, K.S.; Marøy, T.H.; Aarseth, J.H.; Nyland, H.I.; Vedeler, C.A. 2003: Interleukin-10 promoter polymorphisms in patients with Guillain-Barré syndrome. Journal of Neuroimmunology 139(1-2): 81-83

Myhr, K-Morten.; Vågnes, K.S.; Marøy, T.H.; Aarseth, J.H.; Nyland, H.I.; Vedeler, C.A. 2002: Interleukin-10 promoter polymorphisms in patients with multiple sclerosis. Journal of the Neurological Sciences 202(1-2): 93-97

García-Hernández, M.L.; Hernández-Pando, R.; Gariglio, P.; Berumen, J. 2002: Interleukin-10 promotes B16-melanoma growth by inhibition of macrophage functions and induction of tumour and vascular cell proliferation. Immunology 105(2): 231-243

Fujii, S.; Shimizu, K.; Shimizu, T.; Lotze, M.T. 2001: Interleukin-10 promotes the maintenance of antitumor CD8(+) T-cell effector function in situ. Blood 98(7): 2143-2151

Gunnett, C.A.; Heistad, D.D.; Faraci, F.M. 2002: Interleukin-10 protects nitric oxide-dependent relaxation during diabetes: role of superoxide. Diabetes 51(6): 1931-1937

Riley, J.K.; Takeda, K.; Akira, S.; Schreiber, R.D. 1999: Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action. Journal of Biological Chemistry 274(23): 16513-16521

Tsuruma, T.; Yagihashi, A.; Hirata, K.; Torigoe, T.; Araya, J.; Watanabe, N.; Sato, N. 1999: Interleukin-10 reduces natural killer (NK) sensitivity of tumor cells by downregulating NK target structure expression. Cellular Immunology 198(2): 103-110

Veltrop, M.H.; Langermans, J.A.; Thompson, J.; Bancsi, M.J. 2001: Interleukin-10 regulates the tissue factor activity of monocytes in an in vitro model of bacterial endocarditis. Infection and Immunity 69(5): 3197-3202

Hashimoto, T.; Nakamura, M.; Oshika, Y.; Tsuchida, T.; Yamazaki, H.; Kijima, H.; Ueyama, Y.; Minoguchi, K.; Adachi, M.; Ota, H. 2001: Interleukin-10 relieves the inhibitory effects of interferon-gamma on normal human lung fibroblasts. International Journal of Molecular Medicine 7(2): 149-154

Frøen, J.Frederik.; Munkeby, B.H.; Stray-Pedersen, B.; Saugstad, O.Didrik. 2002: Interleukin-10 reverses acute detrimental effects of endotoxin-induced inflammation on perinatal cerebral hypoxia-ischemia. Brain Research 942(1-2): 87-94

Schottelius, A.J.; Mayo, M.W.; Sartor, R.B.; Baldwin, A.S. 1999: Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding. Journal of Biological Chemistry 274(45): 31868-31874

Ghigo, E.; Capo, C.; Raoult, D.; Mege, J.L. 2001: Interleukin-10 stimulates Coxiella burnetii replication in human monocytes through tumor necrosis factor down-modulation: role in microbicidal defect of Q fever. Infection and Immunity 69(4): 2345-2352

Stefano, G.B.; Prevot, V.; Beauvillain, J.C.; Hughes, T.K. 1998: Interleukin-10 stimulation of corticotrophin releasing factor median eminence in rats: Evidence for dependence upon nitric oxide production. Neuroscience Letters 256(3): 167-170

Tebo, J.M.; Kim, H.S.; Gao, J.; Armstrong, D.A.; Hamilton, T.A. 1998: Interleukin-10 suppresses IP-10 gene transcription by inhibiting the production of class I interferon. Blood 92(12): 4742-4749

Yoshidome, H.; Kato, A.; Edwards, M.J.; Lentsch, A.B. 1999: Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: implications of a central role for nuclear factor kappaB. Hepatology 30(1): 203-208

Kontoyiannis, D.; Kotlyarov, A.; Carballo, E.; Alexopoulou, L.; Blackshear, P.J.; Gaestel, M.; Davis, R.; Flavell, R.; Kollias, G. 2001: Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology. EMBO Journal 20(14): 3760-3770

Thanawongnuwech, R.; Thacker, E.L. 2003: Interleukin-10, interleukin-12, and interferon-gamma levels in the respiratory tract following mycoplasma hyopneumoniae and PRRSV infection in pigs. Viral Immunology 16(3): 357-367

Martínez-Escribano, J.A.; Moya-Quiles, M.R.; Muro, M.; Montes-Ares, O.; Hernández-Caselles, T.; Frías, J.F.; Alvarez-López, M.R. 2002: Interleukin-10, interleukin-6 and interferon-gamma gene polymorphisms in melanoma patients. Melanoma Research 12(5): 465-469

Awomoyi, A.A.; Marchant, A.; Howson, J.M.M.; McAdam, K.P.W.J.; Blackwell, J.M.; Newport, M.J. 2002: Interleukin-10, polymorphism in SLC11A1 (formerly NRAMP1), and susceptibility to tuberculosis. Journal of Infectious Diseases 186(12): 1808-1814

Sturlan, S.; Oberhuber, G.; Beinhauer, B.G.; Tichy, B.; Kappel, S.; Wang, J.; Rogy, M.A. 2001: Interleukin-10-deficient mice and inflammatory bowel disease associated cancer development. Carcinogenesis 22(4): 665-671

Makuta, Y.; Sonoda, Y.; Yamamoto, D.; Funakoshi-Tago, M.; Aizu-Yokota, E.; Takebe, Y.; Kasahara, T. 2003: Interleukin-10-induced CCR5 expression in macrophage like HL-60 cells: involvement of Erk1/2 and STAT-3. Biological and Pharmaceutical Bulletin 26(8): 1076-1081

Rowbottom, A.W.; Lepper, M.A.; Garland, R.J.; Cox, C.V.; Corley, E.G. 1999: Interleukin-10-induced CD8 cell proliferation. Immunology 98(1): 80-89

Chen, M.L.; Wang, F.H.; Lee, P.K.; Lin, C.M. 2001: Interleukin-10-induced T cell unresponsiveness can be reversed by dendritic cell stimulation. Immunology Letters 75(2): 91-96

Kohno, T.; Mizukami, H.; Suzuki, M.; Saga, Y.; Takei, Y.; Shimpo, M.; Matsushita, T.; Okada, T.; Hanazono, Y.; Kume, A.; Sato, I.; Ozawa, K. 2003: Interleukin-10-mediated inhibition of angiogenesis and tumor growth in mice bearing VEGF-producing ovarian cancer. Cancer Research 63(16): 5091-5094

Hall, A.M.; Ward, F.J.; Vickers, M.A.; Stott, L.-M.; Urbaniak, S.J.; Barker, R.N. 2002: Interleukin-10-mediated regulatory T-cell responses to epitopes on a human red blood cell autoantigen. Blood 100(13): 4529-4536

Tsuji, N.M.; Mizumachi, K.; Kurisaki, J. 2001: Interleukin-10-secreting Peyer's patch cells are responsible for active suppression in low-dose oral tolerance. Immunology 103(4): 458-464

Müller, G.; Müller, A.; Tüting, T.; Steinbrink, K.; Saloga, J.; Szalma, C.; Knop, J.ür.; Enk, A.H. 2002: Interleukin-10-treated dendritic cells modulate immune responses of naive and sensitized T cells in vivo. Journal of Investigative Dermatology 119(4): 836-841

Steinbrink, K.; Jonuleit, H.; Müller, G.; Schuler, G.; Knop, J.; Enk, A.H. 1999: Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8(+) T cells resulting in a failure to lyse tumor cells. Blood 93(5): 1634-1642

Salazar-Onfray, F. 1999: Interleukin-10: A cytokine used by tumors to escape immunosurveillance. Medical Oncology 16(2): 86-94

Pretolani, M. 1999: Interleukin-10: An anti-inflammatory cytokine with therapeutic potential. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology 29(9): 1164-1171

Opal, S.M.; Wherry, J.C.; Grint, P. 1998: Interleukin-10: potential benefits and possible risks in clinical infectious diseases. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 27(6): 1497-1507

Kimura, T.; Sakabe, H.; Minamiguchi, H.; Fujiki, H.; Abe, T.; Kaneko, H.; Yokota, S.; Nakagawa, H.; Fujii, H.; Tamaki, H.; Ogawa, H.; Sugiyama, H.; Sonoda, Y. 1999: Interleukin-11 (IL-11) enhances clonal proliferation of acute myelogenous leukemia cells with strong expression of the IL-11 receptor alpha chain and signal transducing gp130. Leukemia 13(7): 1018-1027

Cork, B.A.; Li, T.C.; Warren, M.A.; Laird, S.M. 2001: Interleukin-11 (IL-11) in human endometrium: Expression throughout the menstrual cycle and the effects of cytokines on endometrial IL-11 production in vitro. Journal of Reproductive Immunology 50(1): 3-17

Suga, K.; Saitoh, M.; Kokubo, S.; Fukushima, S.; Kaku, S.; Yasuda, S.; Miyata, K. 2003: Interleukin-11 acts synergistically with bone morphogenetic protein-2 to accelerate bone formation in a rat ectopic model. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 23(4): 203-207

Ustun, C.; Dainer, P.M.; Faguet, G.B. 2002: Interleukin-11 administration normalizes the platelet count in a hypersplenic cirrhotic patient. Annals of Hematology 81(10): 609-610

Waxman, A.B.; Mahboubi, K.; Knickelbein, R.G.; Mantell, L.L.; Manzo, N.; Pober, J.S.; Elias, J.A. 2003: Interleukin-11 and interleukin-6 protect cultured human endothelial cells from H2O2-induced cell death. American Journal of Respiratory Cell and Molecular Biology 29(4): 513-522

Takeuchi, Y.; Watanabe, S.; Ishii, G.; Takeda, S.; Nakayama, K.; Fukumoto, S.; Kaneta, Y.; Inoue, D.; Matsumoto, T.; Harigaya, K.; Fujita, T. 2002: Interleukin-11 as a stimulatory factor for bone formation prevents bone loss with advancing age in mice. Journal of Biological Chemistry 277(50): 49011-49018

Zimmerman, M.A.; Selzman, C.H.; Reznikov, L.L.; Raeburn, C.D.; Barsness, K.; McIntyre, R.C.; Hamiel, C.R.; Harken, A.H. 2002: Interleukin-11 attenuates human vascular smooth muscle cell proliferation. American Journal of Physiology. Heart and Circulatory Physiology 283(1): H175-H180

Lai, P.-C.; Cook, H.T.; Smith, J.; Keith, J.C.; Pusey, C.D.; Tam, F.W.K. 2001: Interleukin-11 attenuates nephrotoxic nephritis in Wistar Kyoto rats. Journal of the American Society of Nephrology: Jasn 12(11): 2310-2320

Sheridan, B.C.; Dinarello, C.A.; Meldrum, D.R.; Fullerton, D.A.; Selzman, C.H.; McIntyre, R.C. 1999: Interleukin-11 attenuates pulmonary inflammation and vasomotor dysfunction in endotoxin-induced lung injury. American Journal of Physiology 277(5): L861-L867

Wang, L.S.; Liu, H.J.; Broxmeyer, H.E.; Lu, L. 2000: Interleukin-11 enhancement of VLA-5 mediated adhesion of CD34+ cells from cord blood to fibronectin is associated with the PI-3 kinase pathway. In Vivo 14(2): 331-337

Curti, A.; Ratta, M.; Corinti, S.; Girolomoni, G.; Ricci, F.; Tazzari, P.; Siena, M.; Grande, A.; Fogli, M.; Tura, S.; Lemoli, R.M. 2001: Interleukin-11 induces Th2 polarization of human CD4(+) T cells. Blood 97(9): 2758-2763

Suga, K.; Saitoh, M.; Fukushima, S.; Takahashi, K.; Nara, H.; Yasuda, S.; Miyata, K. 2001: Interleukin-11 induces osteoblast differentiation and acts synergistically with bone morphogenetic protein-2 in C3H10T1/2 cells. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 21(9): 695-707

Curti, A.; Tafuri, A.; Ricciardi, M.R.; Tazzari, P.; Petrucci, M.T.; Fogli, M.; Ratta, M.; Lapalombella, R.; Ferri, E.; Tura, S.; Baccarani, M.; Lemoli, R.M. 2002: Interleukin-11 induces proliferation of human T-cells and its activity is associated with downregulation of p27(kip1). Haematologica 87(4): 373-380

McCloy, M.P.; Roberts, I.A.G.; Howarth, L.J.; Watts, T.L.; Murray, N.A. 2002: Interleukin-11 levels in healthy and thrombocytopenic neonates. Pediatric Research 51(6): 756-760

Bozza, M.; Bliss, J.L.; Dorner, A.J.; Trepicchio, W.L. 2001: Interleukin-11 modulates Th1/Th2 cytokine production from activated CD4+ T cells. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 21(1): 21-30

Campbell, C.L.; Guardiani, R.; Ollari, C.; Nelson, B.E.; Quesenberry, P.J.; Savarese, T.M. 2001: Interleukin-11 receptor expression in primary ovarian carcinomas. Gynecologic Oncology 80(2): 121-127

Bozza, M.; Bliss, J.L.; Maylor, R.; Erickson, J.; Donnelly, L.; Bouchard, P.; Dorner, A.J.; Trepicchio, W.L. 1999: Interleukin-11 reduces T-cell-dependent experimental liver injury in mice. Hepatology 30(6): 1441-1447

Barton, V.A.; Hall, M.A.; Hudson, K.R.; Heath, J.K. 2000: Interleukin-11 signals through the formation of a hexameric receptor complex. Journal of Biological Chemistry 275(46): 36197-36203

Auernhammer, C.J.; Melmed, S. 1999: Interleukin-11 stimulates proopiomelanocortin gene expression and adrenocorticotropin secretion in corticotroph cells: Evidence for a redundant cytokine network in the hypothalamo-pituitary-adrenal axis. Endocrinology 140(4): 1559-1566

Trepicchio, W.L.; Ozawa, M.; Walters, I.B.; Kikuchi, T.; Gilleaudeau, P.; Bliss, J.L.; Schwertschlag, U.; Dorner, A.J.; Krueger, J.G. 1999: Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions. Journal of Clinical Investigation 104(11): 1527-1537

Ropeleski, M.J.; Tang, J.; Walsh-Reitz, M.M.; Musch, M.W.; Chang, E.B. 2003: Interleukin-11-induced heat shock protein 25 confers intestinal epithelial-specific cytoprotection from oxidant stress. Gastroenterology 124(5): 1358-1368

Harandi, A.M.; Svennerholm, B.; Holmgren, J.; Eriksson, K. 2001: Interleukin-12 (IL-12) and IL-18 are important in innate defense against genital herpes simplex virus type 2 infection in mice but are not required for the development of acquired gamma interferon-mediated protective immunity. Journal of Virology 75(14): 6705-6709

Gherardi, M.M.; Ramírez, J.C.; Esteban, M. 2000: Interleukin-12 (IL-12) enhancement of the cellular immune response against human immunodeficiency virus type 1 env antigen in a DNA prime/vaccinia virus boost vaccine regimen is time and dose dependent: suppressive effects of IL-12 boost are mediated by nitric oxide. Journal of Virology 74(14): 6278-6286

Piccotti, J.R.; Li, K.; Chan, S.Y.; Eichwald, E.J.; Bishop, D.K. 1999: Interleukin-12 (IL-12)-driven alloimmune responses in vitro and in vivo: requirement for beta1 subunit of the IL-12 receptor. Transplantation 67(11): 1453-1460

Kelleher, P.; Williams, N.J.; Knight, S.C. 1999: Interleukin-12 administration in retroviral infection of mice increases the potential to produce functional dendritic cells from bone marrow stem cells. Immunology Letters 65(1-2): 51-54

Sigmundsdóttir, H.; Gudjónsson, J.E.; Valdimarsson, H. 2003: Interleukin-12 alone can not enhance the expression of the cutaneous lymphocyte associated antigen (CLA) by superantigen-stimulated T lymphocytes. Clinical and Experimental Immunology 132(3): 430-435

Kobayashi, I.; Nogaki, F.; Kusano, H.; Ono, T.; Miyawaki, S.; Yoshida, H.; Muso, E. 2002: Interleukin-12 alters the physicochemical characteristics of serum and glomerular IgA and modifies glycosylation in a ddY mouse strain having high IgA levels. Nephrology Dialysis Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association 17(12): 2108-2116

Aleman, M.; De La Barrera, S.; Fink, S.; Finiasz, M.; Farina, M.H.; Pizzariello, G.; Sasiain, M.D. 2000: Interleukin-12 amplifies the M. leprae hsp65-cytotoxic response in the presence of tumour necrosis factor-alpha and interferon-gamma generating CD56+ effector cells: interleukin-4 downregulates this effect. Scandinavian Journal of Immunology 51(3): 262-270

Ono, S.; Ueno, C.; Seki, S.; Matsumoto, A.; Mochizuki, H. 2003: Interleukin-12 and -18 induce severe liver injury in mice recovered from peritonitis after sublethal endotoxin challenge. Surgery 134(1): 92-100

Esche, C.; Cai, Q.; Peron, J.M.; Hunter, O.; Subbotin, V.M.; Lotze, M.T.; Shurin, M.R. 2000: Interleukin-12 and Flt3 ligand differentially promote dendropoiesis in vivo. European Journal of Immunology 30(9): 2565-2575

Merendino, R.A.; Gangemi, S.; Misefari, A.; Arena, A.; Capozza, A.B.; Chillemi, S.; D'Ambrosio, F.P. 1999: Interleukin-12 and interleukin-10 production by mononuclear phagocytic cells from breast cancer patients. Immunology Letters 68(2-3): 355-358

Liebau, C.; Baltzer, A.W.A.; Schmidt, S.; Roesel, C.; Karreman, C.; Prisack, J.Bernd.; Bojar, H.; Merk, H. 2002: Interleukin-12 and interleukin-18 induce indoleamine 2,3-dioxygenase (IDO) activity in human osteosarcoma cell lines independently from interferon-gamma. Anticancer Research 22(2a): 931-936

Hou, R.; Goloubeva, O.; Neuberg, D.S.; Strominger, J.L.; Wilson, S.Brian. 2003: Interleukin-12 and interleukin-2-induced invariant natural killer T-cell cytokine secretion and perforin expression independent of T-cell receptor activation. Immunology 110(1): 30-37

Bungiro, R.D.; Goldberg, M.; Suri, P.K.; Knopf, P.M. 1999: Interleukin-12 as an adjuvant for an antischistosome vaccine consisting of adult worm antigens: protection of rats from cercarial challenge. Infection and Immunity 67(5): 2340-2348

Rodolfo, M.; Colombo, M.P. 1999: Interleukin-12 as an adjuvant for cancer immunotherapy. Methods 19(1): 114-120

Greinert, U.; Ernst, M.; Schlaak, M.; Entzian, P. 2001: Interleukin-12 as successful adjuvant in tuberculosis treatment. European Respiratory Journal 17(5): 1049-1051

Hayakawa, S.; Nagai, N.; Kanaeda, T.; Karasaki-Suzuki, M.; Ishii, M.; Chishima, F.; Satoh, K. 1999: Interleukin-12 augments cytolytic activity of peripheral and decidual lymphocytes against choriocarcinoma cell lines and primary culture human placental trophoblasts. American Journal of Reproductive Immunology 41(5): 320-329

Mountford, A.P.; Coulson, P.S.; Cheever, A.W.; Sher, A.; Wilson, R.A.; Wynn, T.A. 1999: Interleukin-12 can directly induce T-helper 1 responses in interferon-gamma (IFN-gamma) receptor-deficient mice, but requires IFN-gamma signalling to downregulate T-helper 2 responses. Immunology 97(4): 588-594

Makrigiannis, A.P.; Musgrave, B.L.; Haeryfar, S.M.; Hoskin, D.W. 2001: Interleukin-12 can replace CD28-dependent T-cell costimulation during nonspecific cytotoxic T lymphocyte induction by anti-CD3 antibody. Journal of Leukocyte Biology 69(1): 113-122

Dickensheets, H.L.; Freeman, S.L.; Donnelly, R.P. 2000: Interleukin-12 differentially regulates expression of IFN-gamma and interleukin-2 in human T lymphoblasts. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 20(10): 897-905

Nagy-Agren, S.E.; Cooney, E.L. 1999: Interleukin-12 enhancement of antigen-specific lymphocyte proliferation correlates with stage of human immunodeficiency virus infection. Journal of Infectious Diseases 179(2): 493-496

Roilides, E.; Tsaparidou, S.; Kadiltsoglou, I.; Sein, T.; Walsh, T.J. 1999: Interleukin-12 enhances antifungal activity of human mononuclear phagocytes against Aspergillus fumigatus: implications for a gamma interferon-independent pathway. Infection and Immunity 67(6): 3047-3050

Sitaraman, S.; Metzger, D.W.; Belloto, R.J.; Infante, A.J.; Wall, K.A. 2000: Interleukin-12 enhances clinical experimental autoimmune myasthenia gravis in susceptible but not resistant mice. Journal of Neuroimmunology 107(1): 73-82

Hanagiri, T.; Imahayashi, S.; Yoshino, I.; So, T.; Eifuku, R.; Yoshimatsu, T.; Takenoyama, M.; Osaki, T.; Nakanishi, R.; Ichiyoshi, Y.; Nomoto, K.; Yasumoto, K. 2000: Interleukin-12 enhances the antitumor activity of cytotoxic T lymphocytes against lung adenocarcinoma engrafted in severe combined immunodeficient mice. International Journal of Clinical Oncology 5(4): 262-268

Yoshimoto, T.; Nagase, H.; Yoneto, T.; Inoue, J.i.; Nariuchi, H. 1998: Interleukin-12 expression in B cells by transformation with Epstein-Barr virus. Biochemical and Biophysical Research Communications 252(3): 556-560

Timoshanko, J.R.; Kitching, A.R.; Holdsworth, S.R.; Tipping, P.G. 2001: Interleukin-12 from intrinsic cells is an effector of renal injury in crescentic glomerulonephritis. Journal of the American Society of Nephrology: Jasn 12(3): 464-471

Milano, S.; D'Agostino, P.; Di Bella, G.; La Rosa, M.; Barbera, C.; Ferlazzo, V.; Mansueto, P.; Rini, G.B.; Barera, A.; Vitale, G.; Mansueto, S.; Cillari, E. 2000: Interleukin-12 in human boutonneuse fever caused by Rickettsia conorii. Scandinavian Journal of Immunology 52(1): 91-95

Hans, W.; Schölmerich, J.; Gross, V.; Falk, W. 2000: Interleukin-12 induced interferon-gamma increases inflammation in acute dextran sulfate sodium induced colitis in mice. European Cytokine Network 11(1): 67-74

Caminschi, I.; Venetsanakos, E.; Leong, C.C.; Garlepp, M.J.; Scott, B.; Robinson, B.W. 1998: Interleukin-12 induces an effective antitumor response in malignant mesothelioma. American Journal of Respiratory Cell and Molecular Biology 19(5): 738-746

Mariani, E.; Meneghetti, A.; Tarozzi, A.; Cattini, L.; Facchini, A. 2000: Interleukin-12 induces efficient lysis of natural killer-sensitive and natural killer-resistant human osteosarcoma cells: The synergistic effect of interleukin-2. Scandinavian Journal of Immunology 51(6): 618-625

Coccia, E.M.; Passini, N.; Battistini, A.; Pini, C.; Sinigaglia, F.; Rogge, L. 1999: Interleukin-12 induces expression of interferon regulatory factor-1 via signal transducer and activator of transcription-4 in human T helper type 1 cells. Journal of Biological Chemistry 274(10): 6698-6703

Li, B.; Cao, D.; Xu, H.; Chang, J.; Zhou, G.; Tian, J.; Li, D.; Theze, J.; Wu, C. 2000: Interleukin-12 induces gene expression in interleukin-2 stimulated human T lymphocytes. European Cytokine Network 11(4): 602-607

Ahmed, Z.; Baker, D.; Cuzner, M.Louise. 2003: Interleukin-12 induces mild experimental allergic encephalomyelitis following local central nervous system injury in the Lewis rat. Journal of Neuroimmunology 140(1-2): 109-117

Lauw, F.N.; Dekkers, P.E.; te Velde, A.A.; Speelman, P.; Levi, M.; Kurimoto, M.; Hack, C.E.; van Deventer, S.J.; van der Poll, T. 1999: Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees. Journal of Infectious Diseases 179(3): 646-652

Lee, J.C.; Kim, D.C.; Gee, M.S.; Saunders, H.Mark.; Sehgal, C.M.; Feldman, M.D.; Ross, S.R.; Lee, W.M.F. 2002: Interleukin-12 inhibits angiogenesis and growth of transplanted but not in situ mouse mammary tumor virus-induced mammary carcinomas. Cancer Research 62(3): 747-755

Schuhknecht, S.; Duensing, S.; Dallmann, I.; Grosse, J.; Reitz, M.; Atzpodien, J. 2002: Interleukin-12 inhibits apoptosis in chronic lymphatic leukemia (CLL) B cells. Cancer BioTherapy and Radiopharmaceuticals 17(5): 495-499

Rais, M.; Wild, J.S.; Choudhury, B.K.; Alam, R.; Stafford, S.; Dharajiya, N.; Sur, S. 2002: Interleukin-12 inhibits eosinophil differentiation from bone marrow stem cells in an interferon-gamma-dependent manner in a mouse model of asthma. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology 32(4): 627-632

Schopf, L.R.; Bliss, J.L.; Lavigne, L.M.; Chung, C.L.; Wolf, S.F.; Sypek, J.P. 1999: Interleukin-12 is capable of generating an antigen-specific Th1-type response in the presence of an ongoing infection-driven Th2-type response. Infection and Immunity 67(5): 2166-2171

Heesen, C.; Sieverding, F.; Schoser, B.G.; Hadji, B.; Kunze, K. 1999: Interleukin-12 is detectable in sera of patients with multiple sclerosis - association with chronic progressive disease course?. European Journal of Neurology 6(5): 591-596

Bussolati, B.; Mariano, F.; Biancone, L.; Foà, R.; David, S.; Cambi, V.; Camussi, G. 1999: Interleukin-12 is synthesized by mesangial cells and stimulates platelet-activating factor synthesis, cytoskeletal reorganization, and cell shape change. American Journal of Pathology 154(2): 623-632

Tsunemi, Y.; Saeki, H.; Nakamura, K.; Sekiya, T.; Hirai, K.; Fujita, H.; Asano, N.; Kishimoto, M.; Tanida, Y.; Kakinuma, T.; Mitsui, H.; Tada, Y.; Wakugawa, M.; Torii, H.; Komine, M.; Asahina, A.; Tamaki, K. 2002: Interleukin-12 p40 gene (IL12B) 3'-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris. Journal of Dermatological Science 30(2): 161-166

Piazzolla, G.; Tortorella, C.; Fiore, G.; Fanelli, M.; Pisconti, A.; Antonaci, S. 2001: Interleukin-12 p40/p70 ratio and in vivo responsiveness to IFN-alpha treatment in chronic hepatitis C. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 21(7): 453-461

Nakahata, E.; Shindoh, Y.; Takayama, T.; Shindoh, C. 2001: Interleukin-12 prevents diaphragm muscle deterioration in a septic animal model. Comparative Biochemistry and Physiology. Part A Molecular and Integrative Physiology 130(4): 653-663

Silva, R.A.; Flórido, M.; Appelberg, R. 2001: Interleukin-12 primes CD4+ T cells for interferon-gamma production and protective immunity during Mycobacterium avium infection. Immunology 103(3): 368-374

Isler, P.; de Rochemonteix, B.G.; Songeon, F.; Boehringer, N.; Nicod, L.P. 1999: Interleukin-12 production by human alveolar macrophages is controlled by the autocrine production of interleukin-10. American Journal of Respiratory Cell and Molecular Biology 20(2): 270-278

Lu, H.; Zhong, G. 1999: Interleukin-12 production is required for chlamydial antigen-pulsed dendritic cells to induce protection against live Chlamydia trachomatis infection. Infection and Immunity 67(4): 1763-1769

Lin, H.; Hikawa, N.; Takenaka, T.; Ishikawa, Y. 2000: Interleukin-12 promotes neurite outgrowth in mouse sympathetic superior cervical ganglion neurons. Neuroscience Letters 278(3): 129-132

Altare, F.; Ensser, A.; Breiman, A.; Reichenbach, J.; Baghdadi, J.E.; Fischer, A.; Emile, J.F.; Gaillard, J.L.; Meinl, E.; Casanova, J.L. 2001: Interleukin-12 receptor beta1 deficiency in a patient with abdominal tuberculosis. Journal of Infectious Diseases 184(2): 231-236

Staretz-Haham, O.; Melamed, R.; Lifshitz, M.; Porat, N.; Fieschi, C.; Casanova, J.Laurent.; Levy, J. 2003: Interleukin-12 receptor beta1 deficiency presenting as recurrent Salmonella infection. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 37(1): 137-140

Afanasyeva, M.; Wang, Y.; Kaya, Z.; Stafford, E.A.; Dohmen, K.M.; Sadighi Akha, A.A.; Rose, N.R. 2001: Interleukin-12 receptor/STAT4 signaling is required for the development of autoimmune myocarditis in mice by an interferon-gamma-independent pathway. Circulation 104(25): 3145-3151

Méndez-Samperio, P.; Ayala-Verdin, H.E.; Trejo-Echeverria, A. 1999: Interleukin-12 regulates the production of Bacille Calmette-Guérin-induced interferon-gamma from human cells in a CD40-dependent manner. Scandinavian Journal of Immunology 50(1): 61-67

Vitolo, D.; Gallo, A.; Ciocci, L.; Cicerone, E.; Baroni, C.D. 2000: Interleukin-12 related cytokine gene expression at a tissue level in carcinomas of the larynx. European Archives of Oto-Rhino-Laryngology: Official Journal of the European Federation of Oto-Rhino-Laryngological Societies: Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 257(5): 290-294

Sakai, M.; Tsuda, H.; Tanebe, K.; Sasaki, Y.; Saito, S. 2002: Interleukin-12 secretion by peripheral blood mononuclear cells is decreased in normal pregnant subjects and increased in preeclamptic patients. American Journal of Reproductive Immunology 47(2): 91-97

Rook, A.H.; Wood, G.S.; Yoo, E.K.; Elenitsas, R.; Kao, D.M.; Sherman, M.L.; Witmer, W.K.; Rockwell, K.A.; Shane, R.B.; Lessin, S.R.; Vonderheid, E.C. 1999: Interleukin-12 therapy of cutaneous T-cell lymphoma induces lesion regression and cytotoxic T-cell responses. Blood 94(3): 902-908

Neumann, D.; Martin, M.U. 2001: Interleukin-12 upregulates the IL-18Rbeta chain in BALB/c thymocytes. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 21(8): 635-642

Adorini, L. 1999: Interleukin-12, a key cytokine in Th1-mediated autoimmune diseases. Cellular and Molecular Life Sciences: Cmls 55(12): 1610-1625

Koyama, T.; Omata, Y.; Maki, Y.; Toyoda, Y.; Saito, A. 1999: Interleukin-12, interferon-gamma and interleukin-4 gene expression in cats infected with Toxoplasma gondii. Journal of Veterinary Medical Science 61(7): 819-821

Vollstedt, S.; Franchini, M.; Alber, G.; Ackermann, M.; Suter, M. 2001: Interleukin-12- and gamma interferon-dependent innate immunity are essential and sufficient for long-term survival of passively immunized mice infected with herpes simplex virus type 1. Journal of Virology 75(20): 9596-9600

Furumoto, K.; Mori, A.; Yamasaki, S.; Inoue, N.; Yang, W.; Nakau, M.; Yasuda, S.; Arii, S.; Imamura, M. 2002: Interleukin-12-gene transduction makes DCs from tumor-bearing mice an effective inducer of tumor-specific immunity in a peritoneal dissemination model. Immunology Letters 83(1): 13-20

Wajchman, J.; Simmons, W.J.; Klein, A.; Koneru, M.; Ponzio, N.M. 2002: Interleukin-12-induced cytotoxicity against syngeneic B cell lymphomas of SJL/J mice. Leukemia Research 26(6): 577-590

Iwadate, Y.; Namba, H.; Sakiyama, S.; Yamaura, A.; Tagawa, M. 2002: Interleukin-12-mediated induction of systemic immunity in the periphery and recruitment of activated T cells into the brain produce limited antitumor effects compared with interleukin-2. International Journal of Molecular Medicine 10(6): 741-747

Vitolo, D.; Ciocci, L.; Ferrauti, P.; Tiboni, F.; Cicerone, E.; Gallo, A.; De Vincentiis, M.; Baroni, C.D. 2000: Interleukin-12-related cytokine gene expression in carcinomas of the breast, lung, and larynx: a study at tissue level. Cancer Detection and Prevention 24(5): 422-434

Kang, B.Y.; Chung, S.W.; Lim, Y.S.; Kim, E.J.; Kim, S.H.; Hwang, S.Y.; Kim, T.S. 1999: Interleukin-12-secreting fibroblasts are more efficient than free recombinant interleukin-12 in inducing the persistent resistance to Mycobacterium avium complex infection. Immunology 97(3): 474-480

Hallez, S.; Detremmerie, O.; Giannouli, C.; Thielemans, K.; Gajewski, T.F.; Burny, A.; Leo, O. 1999: Interleukin-12-secreting human papillomavirus type 16-transformed cells provide a potent cancer vaccine that generates E7-directed immunity. International Journal of Cancer 81(3): 428-437

Steinsvik, T.E.; Aaberge, I.S.; Gaarder, P.I.; Løvik, M. 1999: Interleukin-13 and human immunoglobulin E production in severe combined immunodeficiency mice transplanted with human peripheral blood lymphocytes. Scandinavian Journal of Immunology 49(1): 67-72

Ohshima, K.; Akaiwa, M.; Umeshita, R.; Suzumiya, J.; Izuhara, K.; Kikuchi, M. 2001: Interleukin-13 and interleukin-13 receptor in Hodgkin's disease: Possible autocrine mechanism and involvement in fibrosis. Histopathology 38(4): 368-375

Elias, J.A.; Lee, C.Geun.; Zheng, T.; Shim, Y.; Zhu, Z. 2003: Interleukin-13 and leukotrienes: an intersection of pathogenetic schema. American Journal of Respiratory Cell and Molecular Biology 28(4): 401-404

Kubota, T.; Fang, J.; Kushikata, T.; Krueger, J.M. 2000: Interleukin-13 and transforming growth factor-beta1 inhibit spontaneous sleep in rabbits. American Journal of Physiology. Regulatory Integrative and Comparative Physiology 279(3): R786-R792

Nasu, K.; Fukuda, J.; Sun, B.; Nishida, M.; Miyakawa, I. 2003: Interleukin-13 and tumor necrosis factor-beta differentially regulate the production of cytokines by cultured human endometrial stromal cells. Fertility and Sterility 79(Suppl): 821-827

Horie, S.; Okubo, Y.; Hossain, M.; Sato, E.; Nomura, H.; Koyama, S.; Suzuki, J.; Isobe, M.; Sekiguchi, M. 1997: Interleukin-13 but not interleukin-4 prolongs eosinophil survival and induces eosinophil chemotaxis. Internal Medicine 36(3): 179-185

Husain, S.R.; Puri, R.K. 2000: Interleukin-13 fusion cytotoxin as a potent targeted agent for AIDS-Kaposi's sarcoma xenograft. Blood 95(11): 3506-3513

Lavenu-Bombled, C.; Trainor, C.D.; Makeh, I.; Romeo, P-Henri.; Max-Audit, I. 2002: Interleukin-13 gene expression is regulated by GATA-3 in T cells: role of a critical association of a GATA and two GATG motifs. Journal of Biological Chemistry 277(21): 18313-18321

Tsunemi, Y.; Saeki, H.; Nakamura, K.; Sekiya, T.; Hirai, K.; Kakinuma, T.; Fujita, H.; Asano, N.; Tanida, Y.; Wakugawa, M.; Torii, H.; Tamaki, K. 2002: Interleukin-13 gene polymorphism G4257A is associated with atopic dermatitis in Japanese patients. Journal of Dermatological Science 30(2): 100-107

Woods, J.M.; Amin, M.A.; Katschke, K.J.; Volin, M.V.; Ruth, J.H.; Connors, M.A.; Woodruff, D.C.; Kurata, H.; Arai, K.-I.; Haines, G.K.; Kumar, P.; Koch, A.E. 2002: Interleukin-13 gene therapy reduces inflammation, vascularization, and bony destruction in rat adjuvant-induced arthritis. Human Gene Therapy 13(3): 381-393

Ke, B.; Shen, X-Da.; Lassman, C.R.; Gao, F.; Katori, M.; Busuttil, R.W.; Kupiec-Weglinski, J.W. 2003: Interleukin-13 gene transfer protects rat livers from antigen-independent injury induced by ischemia and reperfusion. Transplantation 75(8): 1118-1123

Woltmann, G.; McNulty, C.A.; Dewson, G.; Symon, F.A.; Wardlaw, A.J. 2000: Interleukin-13 induces PSGL-1/P-selectin-dependent adhesion of eosinophils, but not neutrophils, to human umbilical vein endothelial cells under flow. Blood 95(10): 3146-3152

Lee, J.H.; Kaminski, N.; Dolganov, G.; Grunig, G.; Koth, L.; Solomon, C.; Erle, D.J.; Sheppard, D. 2001: Interleukin-13 induces dramatically different transcriptional programs in three human airway cell types. American Journal of Respiratory Cell and Molecular Biology 25(4): 474-485

Kondo, M.; Tamaoki, J.; Takeyama, K.; Nakata, J.; Nagai, A. 2002: Interleukin-13 induces goblet cell differentiation in primary cell culture from Guinea pig tracheal epithelium. American Journal of Respiratory Cell and Molecular Biology 27(5): 536-541

Booth, B.W.; Adler, K.B.; Bonner, J.C.; Tournier, F.; Martin, L.D. 2001: Interleukin-13 induces proliferation of human airway epithelial cells in vitro via a mechanism mediated by transforming growth factor-alpha. American Journal of Respiratory Cell and Molecular Biology 25(6): 739-743

Nomura, T.; Terada, N.; Kim, W.Jeong.; Nakano, K.; Fukuda, Y.; Wakita, A.; Numata, T.; Konno, A. 2002: Interleukin-13 induces thymus and activation-regulated chemokine (CCL17) in human peripheral blood mononuclear cells. Cytokine 20(2): 49-55

Lee, C.G.; Homer, R.J.; Zhu, Z.; Lanone, S.; Wang, X.; Koteliansky, V.; Shipley, J.M.; Gotwals, P.; Noble, P.; Chen, Q.; Senior, R.M.; Elias, J.A. 2001: Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). Journal of Experimental Medicine 194(6): 809-821

Xu, B.; Bhattacharjee, A.; Roy, B.; Xu, H-Min.; Anthony, D.; Frank, D.A.; Feldman, G.M.; Cathcart, M.K. 2003: Interleukin-13 induction of 15-lipoxygenase gene expression requires p38 mitogen-activated protein kinase-mediated serine 727 phosphorylation of Stat1 and Stat3. Molecular and Cellular Biology 23(11): 3918-3928

Kolios, G.; Wright, K.L.; Linehan, J.D.; Robertson, D.A.; Westwick, J. 2000: Interleukin-13 inhibits nitric oxide production in human colonic mucosa. Hepato-Gastroenterology 47(33): 714-717

Sato, K.; Nagayama, H.; Tadokoro, K.; Juji, T.; Takahashi, T.A. 1999: Interleukin-13 is involved in functional maturation of human peripheral blood monocyte-derived dendritic cells. Experimental Hematology 27(2): 326-336

Whittaker, L.; Niu, N.; Temann, U.-A.; Stoddard, A.; Flavell, R.A.; Ray, A.; Homer, R.J.; Cohn, L. 2002: Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9. American Journal of Respiratory Cell and Molecular Biology 27(5): 593-602

Yang, M.; Hogan, S.P.; Henry, P.J.; Matthaei, K.I.; McKenzie, A.N.; Young, I.G.; Rothenberg, M.E.; Foster, P.S. 2001: Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin. American Journal of Respiratory Cell and Molecular Biology 25(4): 522-530

Oriente, A.; Fedarko, N.S.; Pacocha, S.E.; Huang, S.K.; Lichtenstein, L.M.; Essayan, D.M. 2000: Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblasts. Journal of Pharmacology and Experimental Therapeutics 292(3): 988-994

Zaccone, P.; Phillips, J.; Conget, I.; Gomis, R.; Haskins, K.; Minty, A.; Bendtzen, K.; Cooke, A.; Nicoletti, F. 1999: Interleukin-13 prevents autoimmune diabetes in NOD mice. Diabetes 48(8): 1522-1528

Evans, P.C.; Kilshaw, P.J. 2000: Interleukin-13 protects endothelial cells from apoptosis and activation: association with the protective genes A20 and A1. Transplantation 70(6): 928-934

Joshi, B.H.; Plautz, G.E.; Puri, R.K. 2000: Interleukin-13 receptor alpha chain: a novel tumor-associated transmembrane protein in primary explants of human malignant gliomas. Cancer Research 60(5): 1168-1172

Husain, S.R.; Joshi, B.H.; Puri, R.K. 2001: Interleukin-13 receptor as a unique target for anti-glioblastoma therapy. International Journal of Cancer 92(2): 168-175

Cancino-Díaz, J.C.; Reyes-Maldonado, E.; Bañuelos-Pánuco, C.A.; Jiménez-Zamudio, L.; García-Latorre, E.; León-Dorantes, G.; Blancas-González, F.; Paredes-Cabrera, G.; Cancino-Díaz, M.E. 2002: Interleukin-13 receptor in psoriatic keratinocytes: overexpression of the mRNA and underexpression of the protein. Journal of Investigative Dermatology 119(5): 1114-1120

Kawakami, K.; Kawakami, M.; Joshi, B.H.; Puri, R.K. 2001: Interleukin-13 receptor-targeted cancer therapy in an immunodeficient animal model of human head and neck cancer. Cancer Research 61(16): 6194-6200

Liu, H.; Jacobs, B.S.; Liu, J.; Prayson, R.A.; Estes, M.L.; Barnett, G.H.; Barna, B.P. 2000: Interleukin-13 sensitivity and receptor phenotypes of human glial cell lines: Non-neoplastic glia and low-grade astrocytoma differ from malignant glioma. Cancer Immunology Immunotherapy: Cii 49(6): 319-324

McDonald, P.P.; Russo, M.P.; Ferrini, S.; Cassatella, M.A. 1998: Interleukin-15 (IL-15) induces NF-kappaB activation and IL-8 production in human neutrophils. Blood 92(12): 4828-4835

Matsumoto, K.; Kanmatsuse, K. 1999: Interleukin-15 and interleukin-12 have an additive effect on the release of vascular permeability factor by peripheral blood mononuclear cells in normals and in patients with nephrotic syndrome. Clinical Nephrology 52(1): 10-18

Ashkar, A.A.; Rosenthal, K.L. 2003: Interleukin-15 and natural killer and NKT cells play a critical role in innate protection against genital herpes simplex virus type 2 infection. Journal of Virology 77(18): 10168-10171

Lodolce, J.; Burkett, P.; Koka, R.; Boone, D.; Chien, M.; Chan, F.; Madonia, M.; Chai, S.; Ma, A. 2002: Interleukin-15 and the regulation of lymphoid homeostasis. Molecular Immunology 39(9): 537-544

Carbó, N.; López-Soriano, J.; Costelli, P.; Busquets, S.; Alvarez, B.; Baccino, F.M.; Quinn, L.S.; López-Soriano, F.J.; Argilés, J.M. 2000: Interleukin-15 antagonizes muscle protein waste in tumour-bearing rats. British Journal of Cancer 83(4): 526-531

Gosselin, J.; TomoIu, A.; Gallo, R.C.; Flamand, L. 1999: Interleukin-15 as an activator of natural killer cell-mediated antiviral response. Blood 94(12): 4210-4219

Hjorth-Hansen, H.; Waage, A.; Börset, M. 1999: Interleukin-15 blocks apoptosis and induces proliferation of the human myeloma cell line OH-2 and freshly isolated myeloma cells. British Journal of Haematology 106(1): 28-34

Borger, P.; Kauffman, H.F.; Postma, D.S.; Esselink, M.T.; Vellenga, E. 1999: Interleukin-15 differentially enhances the expression of interferon-gamma and interleukin-4 in activated human (CD4+) T lymphocytes. Immunology 96(2): 207-214

Kacani, L.; Sprinzl, G.M.; Erdei, A.; Dierich, M.P. 1999: Interleukin-15 enhances HIV-1-driven polyclonal B-cell response in vitro. Experimental and Clinical Immunogenetics 16(3): 162-172

Lee, Y.H.; Ely, K.H.; Lepage, A.; Kasper, L.H. 1999: Interleukin-15 enhances host protection against acute Toxoplasma gondii infection in T-cell receptor alpha-/-deficient mice. Parasite Immunology 21(6): 299-306

Mastroianni, C.M.; d'Ettorre, G.; Forcina, G.; Lichtner, M.; Mengoni, F.; D'Agostino, C.; Corpolongo, A.; Massetti, A.P.; Vullo, V. 2000: Interleukin-15 enhances neutrophil functional activity in patients with human immunodeficiency virus infection. Blood 96(5): 1979-1984

Houtkamp, M.A.; van Der Wal, A.C.; de Boer, O.J.; van Der Loos, C.M.; de Boer, P.A.; Moorman, A.F.; Becker, A.E. 2001: Interleukin-15 expression in atherosclerotic plaques: an alternative pathway for T-cell activation in atherosclerosis?. Arteriosclerosis Thrombosis and Vascular Biology 21(7): 1208-1213

Kuniyasu, H.; Oue, N.; Nakae, D.; Tsutsumi, M.; Denda, A.; Tsujiuchi, T.; Yokozaki, H.; Yasui, W. 2001: Interleukin-15 expression is associated with malignant potential in colon cancer cells. Pathobiology: Journal of Immunopathology Molecular and Cellular Biology 69(2): 86-95

d'Ettorre, G.; Forcina, G.; Lichtner, M.; Mengoni, F.; D'Agostino, C.; Massetti, A.P.; Mastroianni, C.M.; Vullo, V. 2002: Interleukin-15 in HIV infection: immunological and virological interactions in antiretroviral-naive and -treated patients. Aids 16(2): 181-188

Maeurer, M.; Seliger, B.; Trinder, P.; Gerdes, J.; Seitzer, U. 1999: Interleukin-15 in mycobacterial infection of antigen-presenting cells. Scandinavian Journal of Immunology 50(3): 280-288

Furmanczyk, P.S.; Quinn, L.S. 2003: Interleukin-15 increases myosin accretion in human skeletal myogenic cultures. Cell Biology International 27(10): 845-851

Hoontrakoon, R.; Chu, H.W.; Gardai, S.J.; Wenzel, S.E.; McDonald, P.; Fadok, V.A.; Henson, P.M.; Bratton, D.L. 2002: Interleukin-15 inhibits spontaneous apoptosis in human eosinophils via autocrine production of granulocyte macrophage-colony stimulating factor and nuclear factor-kappaB activation. American Journal of Respiratory Cell and Molecular Biology 26(4): 404-412

Eisenman, J.; Ahdieh, M.; Beers, C.; Brasel, K.; Kennedy, M.K.; Le, T.; Bonnert, T.P.; Paxton, R.J.; Park, L.S. 2002: Interleukin-15 interactions with interleukin-15 receptor complexes: Characterization and species specificity. Cytokine 20(3): 121-129

Han, G.W.; Iwatsuki, K.; Inoue, M.; Matsui, T.; Nishibu, A.; Akiba, H.; Kaneko, F. 1999: Interleukin-15 is not a constitutive cytokine in the epidermis, but is inducible in culture or inflammatory conditions. Acta Dermato-Venereologica 79(1): 37-40

Lewis, E.; Weiler, M.; Chaimovitz, C.; Douvdevani, A. 2001: Interleukin-15 is the main mediator of lymphocyte proliferation in cultures mixed with human kidney tubular epithelial cells. Transplantation 72(5): 886-890

Hirose, K.; Suzuki, H.; Nishimura, H.; Mitani, A.; Washizu, J.; Matsuguchi, T.; Yoshikai, Y. 1998: Interleukin-15 may be responsible for early activation of intestinal intraepithelial lymphocytes after oral infection with Listeria monocytogenes in rats. Infection and Immunity 66(12): 5677-5683

Carbó, N.; López-Soriano, J.; Costelli, P.; Alvarez, B.; Busquets, S.; Baccino, F.M.; Quinn, L.S.; López-Soriano, F.J.; Argilés, J.M. 2001: Interleukin-15 mediates reciprocal regulation of adipose and muscle mass: A potential role in body weight control. Biochimica et Biophysica Acta 1526(1): 17-24

Masuda, A.; Matsuguchi, T.; Yamaki, K.; Hayakawa, T.; Yoshikai, Y. 2001: Interleukin-15 prevents mouse mast cell apoptosis through STAT6-mediated Bcl-xL expression. Journal of Biological Chemistry 276(28): 26107-26113

Mitani, A.; Nishimura, H.; Hirose, K.; Washizu, J.; Kimura, Y.; Tanaka, S.; Yamamoto, G.; Noguchi, T.; Yoshikai, Y. 1999: Interleukin-15 production at the early stage after oral infection with Listeria monocytogenes in mice. Immunology 97(1): 92-99

Conti, F.; Frappier, J.; Dharancy, S.; Chereau, C.; Houssin, D.; Weill, B.; Calmus, Y. 2003: Interleukin-15 production during liver allograft rejection in humans. Transplantation 76(1): 210-216

Dooms, H.; Van Belle, T.; Desmedt, M.; Rottiers, P.; Grooten, J. 2000: Interleukin-15 redirects the outcome of a tolerizing T-cell stimulus from apoptosis to anergy. Blood 96(3): 1006-1012

Lügering, N.; Kucharzik, T.; Maaser, C.; Kraft, M.; Domschke, W. 1999: Interleukin-15 strongly inhibits interleukin-8 and monocyte chemoattractant protein-1 production in human colonic epithelial cells. Immunology 98(4): 504-509

Möttönen, M.; Isomäki, P.; Luukkainen, R.; Toivanen, P.; Punnonen, J.; Lassila, O. 2000: Interleukin-15 up-regulates the expression of CD154 on synovial fluid T cells. Immunology 100(2): 238-244

Amiel, C.; Darcissac, E.; Truong, M.J.; Dewulf, J.; Loyens, M.; Mouton, Y.; Capron, A.; Bahr, G.M. 1999: Interleukin-16 (IL-16) inhibits human immunodeficiency virus replication in cells from infected subjects, and serum IL-16 levels drop with disease progression. Journal of Infectious Diseases 179(1): 83-91

Wang, H.; Oei, J.; Lui, K.; Henry, R. 2002: Interleukin-16 in tracheal aspirate fluids of newborn infants. Early Human Development 67(1-2): 79-86

Truong, M.J.; Darcissac, E.C.; Hermann, E.; Dewulf, J.; Capron, A.; Bahr, G.M. 1999: Interleukin-16 inhibits human immunodeficiency virus type 1 entry and replication in macrophages and in dendritic cells. Journal of Virology 73(8): 7008-7013

Mathy, N.L.; Scheuer, W.; Lanzendörfer, M.; Honold, K.; Ambrosius, D.; Norley, S.; Kurth, R. 2000: Interleukin-16 stimulates the expression and production of pro-inflammatory cytokines by human monocytes. Immunology 100(1): 63-69

Stoitzner, P.; Ratzinger, G.; Koch, F.; Janke, K.; Schöller, T.; Kaser, A.; Tilg, H.; Cruikshank, W.W.; Fritsch, P.; Romani, N. 2001: Interleukin-16 supports the migration of Langerhans cells, partly in a CD4-independent way. Journal of Investigative Dermatology 116(5): 641-649

Woltman, A.M.; DE Haij, S.; Boonstra, J.G.; Gobin, S.J.P.; Daha, M.R.; Kooten, C.V. 2000: Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells. Journal of the American Society of Nephrology: Jasn 11(11): 2044-2055

Ye, P.; Garvey, P.B.; Zhang, P.; Nelson, S.; Bagby, G.; Summer, W.R.; Schwarzenberger, P.; Shellito, J.E.; Kolls, J.K. 2001: Interleukin-17 and lung host defense against Klebsiella pneumoniae infection. American Journal of Respiratory Cell and Molecular Biology 25(3): 335-340

Tang, J.L.; Subbotin, V.M.; Antonysamy, M.A.; Troutt, A.B.; Rao, A.S.; Thomson, A.W. 2001: Interleukin-17 antagonism inhibits acute but not chronic vascular rejection. Transplantation 72(2): 348-350

Subramaniam, S.V.; Pearson, L.L.; Adunyah, S.E. 1999: Interleukin-17 induces rapid tyrosine phosphorylation and activation of raf-1 kinase in human monocytic progenitor cell line U937. Biochemical and Biophysical Research Communications 259(1): 172-177

Hsieh, H-Guey.; Loong, C-Chang.; Lin, C-Yuang. 2002: Interleukin-17 induces src/MAPK cascades activation in human renal epithelial cells. Cytokine 19(4): 159-174

Benchetrit, F.; Ciree, A.; Vives, V.; Warnier, G.; Gey, A.; Sautès-Fridman, C.; Fossiez, F.ço.; Haicheur, N.; Fridman, W.H.; Tartour, E. 2002: Interleukin-17 inhibits tumor cell growth by means of a T-cell-dependent mechanism. Blood 99(6): 2114-2121

Albanesi, C.; Scarponi, C.; Cavani, A.; Federici, M.; Nasorri, F.; Girolomoni, G. 2000: Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes. Journal of Investigative Dermatology 115(1): 81-87

Matusevicius, D.; Kivisäkk, P.; He, B.; Kostulas, N.; Ozenci, V.; Fredrikson, S.; Link, H. 1999: Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Multiple Sclerosis 5(2): 101-104

Hellings, P.W.; Kasran, A.; Liu, Z.; Vandekerckhove, P.; Wuyts, A.; Overbergh, L.; Mathieu, C.; Ceuppens, J.L. 2003: Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma. American Journal of Respiratory Cell and Molecular Biology 28(1): 42-50

Numasaki, M.; Fukushi, J.-i.; Ono, M.; Narula, S.K.; Zavodny, P.J.; Kudo, T.; Robbins, P.D.; Tahara, H.; Lotze, M.T. 2003: Interleukin-17 promotes angiogenesis and tumor growth. Blood 101(7): 2620-2627

Takaya, H.; Andoh, A.; Makino, J.; Shimada, M.; Tasaki, K.; Araki, Y.; Bamba, S.; Hata, K.; Fujiyama, Y.; Bamba, T. 2002: Interleukin-17 stimulates chemokine (interleukin-8 and monocyte chemoattractant protein-1) secretion in human pancreatic periacinar myofibroblasts. Scandinavian Journal of Gastroenterology 37(2): 239-245

Trajkovic, V.; Stosic-Grujicic, S.; Samardzic, T.; Markovic, M.; Miljkovic, D.; Ramic, Z.; Mostarica Stojkovic, M. 2001: Interleukin-17 stimulates inducible nitric oxide synthase activation in rodent astrocytes. Journal of Neuroimmunology 119(2): 183-191

Jones, C.E.; Chan, K. 2002: Interleukin-17 stimulates the expression of interleukin-8, growth-related oncogene-alpha, and granulocyte-colony-stimulating factor by human airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology 26(6): 748-753

Matsumoto, K.; Kanmatsuse, K. 2003: Interleukin-17 stimulates the release of pro-inflammatory cytokines by blood monocytes in patients with IgA nephropathy. Scandinavian Journal of Urology and Nephrology 37(2): 164-171

Van bezooijen, R.L.; Farih-Sips, H.C.; Papapoulos, S.E.; Löwik, C.W. 1999: Interleukin-17: a new bone acting cytokine in vitro. Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research 14(9): 1513-1521

Dinarello, C.A. 1999: Interleukin-18. Methods 19(1): 121-132

Gracie, J.Alastair.; Robertson, S.E.; McInnes, I.B. 2003: Interleukin-18. Journal of Leukocyte Biology 73(2): 213-224

Sugawara, I. 2000: Interleukin-18 (IL-18) and infectious diseases, with special emphasis on diseases induced by intracellular pathogens. Microbes and Infection 2(10): 1257-1263

Son, Y.I.; Dallal, R.M.; Mailliard, R.B.; Egawa, S.; Jonak, Z.L.; Lotze, M.T. 2001: Interleukin-18 (IL-18) synergizes with IL-2 to enhance cytotoxicity, interferon-gamma production, and expansion of natural killer cells. Cancer Research 61(3): 884-888

Cao, R.; Farnebo, J.; Kurimoto, M.; Cao, Y. 1999: Interleukin-18 acts as an angiogenesis and tumor suppressor. Faseb Journal: Official Publication of the Federation of American Societies for Experimental Biology 13(15): 2195-2202

Merendino, R.Alba.; Di Rosa, A.Enrico.; Di Pasquale, G.; Minciullo, P.Lucia.; Mangraviti, C.; Costantino, A.; Ruello, A.; Gangemi, S. 2002: Interleukin-18 and CD30 serum levels in patients with moderate-severe depression. Mediators of Inflammation 11(4): 265-267

Kanai, T.; Watanabe, M.; Okazawa, A.; Sato, T.; Hibi, T. 2001: Interleukin-18 and Crohn's disease. Digestion 63(Suppl): 37-42

Dinarello, C.A.; Fantuzzi, G. 2003: Interleukin-18 and host defense against infection. Journal of Infectious Diseases 187(Suppl 2): S370-S384

Kawakami, K. 2002: Interleukin-18 and host defense against infectious pathogens. Journal of ImmunoTherapy 25(Suppl): S12-S19

Yamada, N.; Niwa, S.; Tsujimura, T.; Iwasaki, T.; Sugihara, A.; Futani, H.; Hayashi, S.; Okamura, H.; Akedo, H.; Terada, N. 2002: Interleukin-18 and interleukin-12 synergistically inhibit osteoclastic bone-resorbing activity. Bone 30(6): 901-908

Matsumoto, K.; Kanmatsuse, K. 2000: Interleukin-18 and interleukin-12 synergize to stimulate the production of vascular permeability factor by T lymphocytes in normal subjects and in patients with minimal-change nephrotic syndrome. Nephron 85(2): 127-133

Carrascal, M.Teresa.; Mendoza, L.; Valcárcel, M.; Salado, C.; Egilegor, E.; Tellería, N.; Vidal-Vanaclocha, F.; Dinarello, C.A. 2003: Interleukin-18 binding protein reduces b16 melanoma hepatic metastasis by neutralizing adhesiveness and growth factors of sinusoidal endothelium. Cancer Research 63(2): 491-497

Novick, D.; Kim, S.H.; Fantuzzi, G.; Reznikov, L.L.; Dinarello, C.A.; Rubinstein, M. 1999: Interleukin-18 binding protein: A novel modulator of the Th1 cytokine response. Immunity 10(1): 127-136

Pugliese, A.; Gennero, L.; Vidotto, V.; Speranza, F.; Tambini, R.; Torre, D. 2002: Interleukin-18 enhances HIV-1 production in a human chronically-infected T cell line (H9-V). Cell Biochemistry and Function 20(4): 333-337

Kumano, K.; Nakao, A.; Nakajima, H.; Hayashi, F.; Kurimoto, M.; Okamura, H.; Saito, Y.; Iwamoto, I. 1999: Interleukin-18 enhances antigen-induced eosinophil recruitment into the mouse airways. American Journal of Respiratory and Critical Care Medicine 160(3): 873-878

Puren, A.J.; Razeghi, P.; Fantuzzi, G.; Dinarello, C.A. 1998: Interleukin-18 enhances lipopolysaccharide-induced interferon-gamma production in human whole blood cultures. Journal of Infectious Diseases 178(6): 1830-1834

Jander, S.; Schroeter, M.; Stoll, G. 2002: Interleukin-18 expression after focal ischemia of the rat brain: association with the late-stage inflammatory response. Journal of cerebral blood flow and metabolism: official journal of the International Society of Cerebral Blood Flow and Metabolism 22(1): 62-70

Yao, L.; Setsuda, J.; Sgadari, C.; Cherney, B.; Tosato, G. 2001: Interleukin-18 expression induced by Epstein-Barr virus-infected cells. Journal of Leukocyte Biology 69(5): 779-784

Weijer, S.; Sewnath, M.E.; de Vos, A.F.; Florquin, S.; van der Sluis, K.; Gouma, D.J.; Takeda, K.; Akira, S.; van der Poll, T. 2003: Interleukin-18 facilitates the early antimicrobial host response to Escherichia coli peritonitis. Infection and Immunity 71(10): 5488-5497

Kimura, T.; Shibata, M.; Fukuzawa, M.; Hirose, K. 2000: Interleukin-18 gene transfer to Lewis lung carcinoma and its effect on tumor growth in vivo. Nichidai Igaku Zasshi 59(1): 21-28

Zwijnenburg, P.J.G.; van der Poll, T.; Florquin, S.; Akira, S.; Takeda, K.; Roord, J.J.; van Furth, A.Marceline. 2003: Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitis. Journal of Neuroimmunology 138(1-2): 31-37

Schultz, M.J.; Knapp, S.; Florquin, S.; Pater, J.; Takeda, K.; Akira, S.; van der Poll, T. 2003: Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa. Infection and Immunity 71(4): 1630-1634

Arai, N.; Akamatsu, S.; Arai, S.; Toshimori, Y.; Hanaya, T.; Tanimoto, T.; Ikeda, M.; Tomura, M.; Fujiwara, H.; Kurimoto, M. 2000: Interleukin-18 in combination with IL-2 enhances natural killer cell activity without inducing large amounts of IFN-gamma in vivo. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 20(2): 217-224

Adams, K.M.; Mandel, L.S.; Guthrie, K.A.; Atkinson, M.Wendy. 2003: Interleukin-18 in the plasma of women with preeclampsia. American Journal of Obstetrics and Gynecology 188(5): 1234-1237

Hosohara, K.; Ueda, H.; Kashiwamura, S.-I.; Yano, T.; Ogura, T.; Marukawa, S.; Okamura, H. 2002: Interleukin-18 induces acute biphasic reduction in the levels of circulating leukocytes in mice. Clinical and Diagnostic Laboratory Immunology 9(4): 777-783

Tsuji-Takayama, K.; Aizawa, Y.; Okamoto, I.; Kojima, H.; Koide, K.; Takeuchi, M.; Ikegami, H.; Ohta, T.; Kurimoto, M. 1999: Interleukin-18 induces interferon-gamma production through NF-kappaB and NFAT activation in murine T helper type 1 cells. Cellular Immunology 196(1): 41-50

Netea, M.G.; Kullberg, B.J.; Verschueren, I.; Van Der Meer, J.W. 2000: Interleukin-18 induces production of proinflammatory cytokines in mice: no intermediate role for the cytokines of the tumor necrosis factor family and interleukin-1beta. European Journal of Immunology 30(10): 3057-3060

Morel, J.C.; Park, C.C.; Kumar, P.; Koch, A.E. 2001: Interleukin-18 induces rheumatoid arthritis synovial fibroblast CXC chemokine production through NFkappaB activation. Laboratory Investigation; A Journal of Technical Methods and Pathology 81(10): 1371-1383

Kimura, K.; Kakimi, K.; Wieland, S.; Guidotti, L.G.; Chisari, F.V. 2002: Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice. Journal of Virology 76(21): 10702-10707

Choi, H.J.; Dinarello, C.A.; Shapiro, L. 2001: Interleukin-18 inhibits human immunodeficiency virus type 1 production in peripheral blood mononuclear cells. Journal of Infectious Diseases 184(5): 560-568

Yamashita, K.; Iwasaki, T.; Tsujimura, T.; Sugihara, A.; Yamada, N.; Ueda, H.; Okamura, H.; Futani, H.; Maruo, S.; Terada, N. 2002: Interleukin-18 inhibits lodging and subsequent growth of human multiple myeloma cells in the bone marrow. Oncology Reports 9(6): 1237-1244

Iwasaki, T.; Yamashita, K.; Tsujimura, T.; Kashiwamura, S.-i.; Tsutsui, H.; Kaisho, T.; Sugihara, A.; Yamada, N.; Mukai, M.; Yoneda, T.; Okamura, H.; Akedo, H.; Terada, N. 2002: Interleukin-18 inhibits osteolytic bone metastasis by human lung cancer cells possibly through suppression of osteoclastic bone-resorption in nude mice. Journal of ImmunoTherapy 25(Suppl 1): S52-S60

Hedtjärn, M.; Leverin, A.-L.; Eriksson, K.; Blomgren, K.; Mallard, C.; Hagberg, H. 2002: Interleukin-18 involvement in hypoxic-ischemic brain injury. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 22(14): 5910-5919

Cornish, J.; Gillespie, M.T.; Callon, K.E.; Horwood, N.J.; Moseley, J.M.; Reid, I.R. 2003: Interleukin-18 is a novel mitogen of osteogenic and chondrogenic cells. Endocrinology 144(4): 1194-1201

Blankenberg, S.; Tiret, L.; Bickel, C.; Peetz, D.; Cambien, Fçois.; Meyer, Jürgen.; Rupprecht, H.J. 2002: Interleukin-18 is a strong predictor of cardiovascular death in stable and unstable angina. Circulation 106(1): 24-30

Ohnishi, H.; Kato, Z.; Watanabe, M.; Fukutomi, O.; Inoue, R.; Teramoto, T.; Kondo, N. 2003: Interleukin-18 is associated with the severity of atopic dermatitis. Allergology International 52(3): 123-130

Tanaka, T.; Tsutsui, H.; Yoshimoto, T.; Kotani, M.; Matsumoto, M.; Fujita, A.; Wang, W.; Higa, S.; Koshimoto, T.; Nakanishi, K.; Suemura, M. 2001: Interleukin-18 is elevated in the sera from patients with atopic dermatitis and from atopic dermatitis model mice, NC/Nga. International Archives of Allergy and Immunology 125(3): 236-240

Jander, S.; Stoll, G. 2001: Interleukin-18 is induced in acute inflammatory demyelinating polyneuropathy. Journal of Neuroimmunology 114(1-2): 253-258

Hong, T.P.; Andersen, N.A.; Nielsen, K.; Karlsen, A.E.; Fantuzzi, G.; Eizirik, D.L.; Dinarello, C.A.; Mandrup-Poulsen, T. 2000: Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma. European Cytokine Network 11(2): 193-205

Billaut-Mulot, O.; Idziorek, T.; Ban, E.; Kremer, L.; Dupré, L.; Loyens, M.; Riveau, G.; Locht, C.; Capron, A.; Bahr, G.M. 2000: Interleukin-18 modulates immune responses induced by HIV-1 Nef DNA prime/protein boost vaccine. Vaccine 19(1): 95-102

Ishikura, T.; Kanai, T.; Uraushihara, K.; IIyama, R.; Makita, S.; Totsuka, T.; Yamazaki, M.; Sawada, T.; Nakamura, T.; Miyata, T.; Kitahora, T.; Hibi, T.; Hoshino, T.; Watanabe, M. 2003: Interleukin-18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin-18 transgenic mice. Journal of Gastroenterology and Hepatology 18(8): 960-969

Pollock, K.G.J.; Conacher, M.; Wei, X-Qing.; Alexander, J.; Brewer, J.M. 2003: Interleukin-18 plays a role in both the alum-induced T helper 2 response and the T helper 1 response induced by alum-adsorbed interleukin-12. Immunology 108(2): 137-143

Kretowski, A.; Mironczuk, K.; Karpinska, A.; Bojaryn, U.; Kinalski, M.; Puchalski, Z.; Kinalska, I. 2002: Interleukin-18 promoter polymorphisms in type 1 diabetes. Diabetes 51(11): 3347-3349

Fujioka, N.; Akazawa, R.; Ohashi, K.; Fujii, M.; Ikeda, M.; Kurimoto, M. 1999: Interleukin-18 protects mice against acute herpes simplex virus type 1 infection. Journal of Virology 73(3): 2401-2409

Yoshida, A.; Kand, T.; Tanaka, T.; Yokoyama, T.; Kurimoto, M.; Tamura, J.; Kobayashi, I. 2002: Interleukin-18 reduces expression of cardiac tumor necrosis factor-alpha and atrial natriuretic peptide in a murine model of viral myocarditis. Life Sciences 70(11): 1225-1234

Reddy, P.; Teshima, T.; Kukuruga, M.; Ordemann, R.; Liu, C.; Lowler, K.; Ferrara, J.L. 2001: Interleukin-18 regulates acute graft-versus-host disease by enhancing Fas-mediated donor T cell apoptosis. Journal of Experimental Medicine 194(10): 1433-1440

Klein, S.A.; Klebba, C.; Kauschat, D.; Pape, M.; Ozmen, L.; Hoelzer, D.; Ottmann, O.G.; Kalina, U. 2000: Interleukin-18 stimulates HIV-1 replication in a T-cell line. European Cytokine Network 11(1): 47-52

Ogura, T.; Ueda, H.; Hosohara, K.; Tsuji, R.; Nagata, Y.; Kashiwamura, S.; Okamura, H. 2001: Interleukin-18 stimulates hematopoietic cytokine and growth factor formation and augments circulating granulocytes in mice. Blood 98(7): 2101-2107

Gardella, S.; Andrei, C.; Costigliolo, S.; Poggi, A.; Zocchi, M.R.; Rubartelli, A. 1999: Interleukin-18 synthesis and secretion by dendritic cells are modulated by interaction with antigen-specific T cells. Journal of Leukocyte Biology 66(2): 237-241

Makiishi-Shimobayashi, C.; Tsujimura, T.; Iwasaki, T.; Yamada, N.; Sugihara, A.; Okamura, H.; Hayashi, S.; Terada, N. 2001: Interleukin-18 up-regulates osteoprotegerin expression in stromal/osteoblastic cells. Biochemical and Biophysical Research Communications 281(2): 361-366

Setsuda, J.; Teruya-Feldstein, J.; Harris, N.L.; Ferry, J.A.; Sorbara, L.; Gupta, G.; Jaffe, E.S.; Tosato, G. 1999: Interleukin-18, interferon-gamma, IP-10, and Mig expression in Epstein-Barr virus-induced infectious mononucleosis and posttransplant lymphoproliferative disease. American Journal of Pathology 155(1): 257-265

Dayer, J.M. 1999: Interleukin-18, rheumatoid arthritis, and tissue destruction. Journal of Clinical Investigation 104(10): 1337-1339

Mallat, Z.; Corbaz, A.; Scoazec, A.; Graber, P.; Alouani, S.; Esposito, B.; Humbert, Y.; Chvatchko, Y.; Tedgui, A. 2001: Interleukin-18/interleukin-18 binding protein signaling modulates atherosclerotic lesion development and stability. Circulation Research 89(7): E41-E45

Mallat, Z.; Silvestre, J-Sébastien.; Le Ricousse-Roussanne, S.; Lecomte-Raclet, L.; Corbaz, A.; Clergue, M.; Duriez, M.; Barateau, Véronique.; Akira, S.; Tedgui, A.; Tobelem, Gérard.; Chvatchko, Y.; Lévy, B.I. 2002: Interleukin-18/interleukin-18 binding protein signaling modulates ischemia-induced neovascularization in mice hindlimb. Circulation Research 91(5): 441-448

Lebel-Binay, S.; Berger, A.; Zinzindohoué, F.; Cugnenc, P.; Thiounn, N.; Fridman, W.H.; Pagès, F. 2000: Interleukin-18: biological properties and clinical implications. European Cytokine Network 11(1): 15-26

Fidani, L.; Goulas, A.; Mirtsou, V.; Petersen, R.C.; Tangalos, E.; Crook, R.; Hardy, J. 2002: Interleukin-1A polymorphism is not associated with late onset Alzheimer's disease. Neuroscience Letters 323(1): 81-83

Kumar, S.; Hanning, C.R.; Brigham-Burke, M.R.; Rieman, D.J.; Lehr, R.; Khandekar, S.; Kirkpatrick, R.B.; Scott, G.F.; Lee, J.C.; Lynch, F.J.; Gao, W.; Gambotto, A.; Lotze, M.T. 2002: Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-gamma production. Cytokine 18(2): 61-71

Sawai, H.; Funahashi, H.; Yamamoto, M.; Okada, Y.; Hayakawa, T.; Tanaka, M.; Takeyama, H.; Manabe, T. 2003: Interleukin-1alpha enhances integrin alpha(6)beta(1) expression and metastatic capability of human pancreatic cancer. Oncology 65(2): 167-173

Mino, T.; Sugiyama, E.; Taki, H.; Kuroda, A.; Yamashita, N.; Maruyama, M.; Kobayashi, M. 1998: Interleukin-1alpha and tumor necrosis factor alpha synergistically stimulate prostaglandin E2-dependent production of interleukin-11 in rheumatoid synovial fibroblasts. Arthritis and Rheumatism 41(11): 2004-2013

Furuya, Y.; Ichikura, T.; Mochizuki, H. 1999: Interleukin-1alpha concentration in tumors as a risk factor for liver metastasis in gastric cancer. Surgery Today 29(3): 288-289

Kubota, Y.; Oka, S.; Nakagawa, S.; Shirasuna, K. 2002: Interleukin-1alpha enhances type I collagen-induced activation of matrix metalloproteinase-2 in odontogenic keratocyst fibroblasts. Journal of Dental Research 81(1): 23-27

Yang, Z.J.; Blaha, V.; Meguid, M.M.; Laviano, A.; Oler, A.; Zadak, Z. 1999: Interleukin-1alpha injection into ventromedial hypothalamic nucleus of normal rats depresses food intake and increases release of dopamine and serotonin. Pharmacology Biochemistry and Behavior 62(1): 61-65

Giri, D.; Ittmann, M. 2000: Interleukin-1alpha is a paracrine inducer of FGF7, a key epithelial growth factor in benign prostatic hyperplasia. American Journal of Pathology 157(1): 249-255

Salven, P.; Hattori, K.; Heissig, B.; Rafii, S. 2002: Interleukin-1alpha promotes angiogenesis in vivo via VEGFR-2 pathway by inducing inflammatory cell VEGF synthesis and secretion. Faseb Journal: Official Publication of the Federation of American Societies for Experimental Biology 16(11): 1471-1473

Toratani, A.; Sawada, S.; Kono, Y.; Higaki, T.; Imamura, H.; Tada, Y.; Yamasaki, S.; Sato, T.; Komatsu, S.; Akamatsu, N.; Tamagaki, T.; Nakagawa, K.; Tsuji, H.; Nakagawa, M. 1999: Interleukin-1alpha stimulated prostacyclin release by increasing gene transcription of prostaglandin H synthase and phospholipase A2 in human vascular endothelial cells. Journal of Cardiovascular Pharmacology 33(6): 843-851

Svechnikov, K.; Stocco, D.M.; Söder, O. 2003: Interleukin-1alpha stimulates steroidogenic acute regulatory protein expression via p38 MAP kinase in immature rat Leydig cells. Journal of Molecular Endocrinology 30(1): 59-67

Li, X.; Eckard, J.; Shah, R.; Malluck, C.; Frenkel, K. 2002: Interleukin-1alpha up-regulation in vivo by a potent carcinogen 7,12-dimethylbenz(a)anthracene (DMBA) and control of DMBA-induced inflammatory responses. Cancer Research 62(2): 417-423

Davis-Whitenack, M.L.; Adeleye, B.; Stoecker, B.J. 1999: Interleukin-1alpha-induced changes in chromium-51 absorption, tissue retention, and urinary excretion in rats. Biological Trace Element Research 68(2): 175-180

Kohen, P.; Castro, A.; Caballero-Campo, P.; Castro, O.; Vega, M.; Makrigiannakis, A.; Simón, C.; Carvallo, P.; Devoto, L. 1999: Interleukin-1beta (IL-1beta) is a modulator of human luteal cell steroidogenesis: localization of the IL type I system in the corpus luteum. Journal of Clinical Endocrinology and Metabolism 84(11): 4239-4245

Morton, N.M.; de Groot, R.P.; Cawthorne, M.A.; Emilsson, V. 1999: Interleukin-1beta activates a short STAT-3 isoform in clonal insulin-secreting cells. Febs Letters 442(1): 57-60

Casamenti, F.; Prosperi, C.; Scali, C.; Giovannelli, L.; Colivicchi, M.A.; Faussone-Pellegrini, M.S.; Pepeu, G. 1999: Interleukin-1beta activates forebrain glial cells and increases nitric oxide production and cortical glutamate and GABA release in vivo: implications for Alzheimer's disease. Neuroscience 91(3): 831-842

Brown, N.L.; Alvi, S.A.; Elder, M.G.; Bennett, P.R.; Sullivan, M.H. 1998: Interleukin-1beta and bacterial endotoxin change the metabolism of prostaglandins E2 and F2alpha in intact term fetal membranes. Placenta 19(8): 625-630

Abe, T.; Sugano, E.; Saigo, Y.; Tamai, M. 2003: Interleukin-1beta and barrier function of retinal pigment epithelial cells (ARPE-19): aberrant expression of junctional complex molecules. IOVS Investigative Ophthalmology and Visual Science 44(9): 4097-4104

Slisli, Y.; de Beaurepaire, R. 1999: Interleukin-1beta and calcitonin, but not corticotropin-releasing factor, alter sleep cycles when injected into the rat hypothalamic lateral paraventricular area. Neuroscience Letters 265(1): 29-32

Zumwalt, J.W.; Thunstrom, B.J.; Spangelo, B.L. 1999: Interleukin-1beta and catecholamines synergistically stimulate interleukin-6 release from rat C6 glioma cells in vitro: a potential role for lysophosphatidylcholine. Endocrinology 140(2): 888-896

van der Velden, V.H.; Verheggen, M.M.; Bernasconi, S.; Sozzani, S.; Naber, B.A.; van der Linden-van Beurden, C.A.; Hoogsteden, H.C.; Mantovani, A.; Versnel, M. 1998: Interleukin-1beta and interferon-gamma differentially regulate release of monocyte chemotactic protein-1 and interleukin-8 by human bronchial epithelial cells. European Cytokine Network 9(3): 269-277

Chen, H-Yi.; Chen, W-Chi.; Wu, M-Chen.; Tsai, F-Jen.; Lin, C-Chieh. 2003: Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphism in postmenopausal women: correlation to bone mineral density and susceptibility to osteoporosis. Maturitas 44(1): 49-54

van der Paardt, M.; Crusius, J.B.A.; García-González, M.A.; Baudoin, P.; Kostense, P.J.; Alizadeh, B.Z.; Dijkmans, B.A.C.; Peña, A.S.; van der Horst-Bruinsma, I.E. 2002: Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in ankylosing spondylitis. Rheumatology 41(12): 1419-1423

Huang, C.M.; Tsai, F.J.; Wu, J.Y.; Wu, M.C. 2001: Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in rheumatoid arthritis. Scandinavian Journal of Rheumatology 30(4): 225-228

de Kluijver, J.; Grünberg, K.; Pons, D.; de Klerk, E.P.A.; Dick, C.R.; Sterk, P.J.; Hiemstra, P.S. 2003: Interleukin-1beta and interleukin-1ra levels in nasal lavages during experimental rhinovirus infection in asthmatic and non-asthmatic subjects. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology 33(10): 1415-1418

Ye, S.; Mozayeni, P.; Gamburd, M.; Zhong, H.; Campese, V.M. 2000: Interleukin-1beta and neurogenic control of blood pressure in normal rats and rats with chronic renal failure. American Journal of Physiology. Heart and Circulatory Physiology 279(6): H2786-H2796

Lawrence, C.B.; Allan, S.M.; Rothwell, N.J. 1998: Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat. European Journal of Neuroscience 10(3): 1188-1195

Tüter, G.; Kurtiş, B.; Serdar, M. 2001: Interleukin-1beta and thiobarbituric acid reactive substance (TBARS) levels after phase I periodontal therapy in patients with chronic periodontitis. Journal of Periodontology 72(7): 883-888

Siwik, D.A.; Chang, D.L.; Colucci, W.S. 2000: Interleukin-1beta and tumor necrosis factor-alpha decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro. Circulation Research 86(12): 1259-1265

Tang, R.B.; Lee, B.H.; Chung, R.L.; Chen, S.J.; Wong, T.T. 2001: Interleukin-1beta and tumor necrosis factor-alpha in cerebrospinal fluid of children with bacterial meningitis. Child's Nervous System: Chns: Official Journal of the International Society for Pediatric Neurosurgery 17(8): 453-456

Okuno, T.; Andoh, A.; Bamba, S.; Araki, Y.; Fujiyama, Y.; Fujiyama, M.; Bamba, T. 2002: Interleukin-1beta and tumor necrosis factor-alpha induce chemokine and matrix metalloproteinase gene expression in human colonic subepithelial myofibroblasts. Scandinavian Journal of Gastroenterology 37(3): 317-324

Hellwig-Bürgel, T.; Rutkowski, K.; Metzen, E.; Fandrey, J.; Jelkmann, W. 1999: Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1. Blood 94(5): 1561-1567

Hofbauer, L.C.; Lacey, D.L.; Dunstan, C.R.; Spelsberg, T.C.; Riggs, B.L.; Khosla, S. 1999: Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells. Bone 25(3): 255-259

Geiser, T.; Jarreau, P.H.; Atabai, K.; Matthay, M.A. 2000: Interleukin-1beta augments in vitro alveolar epithelial repair. American Journal of Physiology. Lung Cellular and Molecular Physiology 279(6): L1184-L1190

Byrne, S.N.; Halliday, G.M.; Johnston, L.J.; King, N.J. 2001: Interleukin-1beta but not tumor necrosis factor is involved in West Nile virus-induced Langerhans cell migration from the skin in C57BL/6 mice. Journal of Investigative Dermatology 117(3): 702-709

Akasu, T.; Tsurusaki, M. 1999: Interleukin-1beta causes a biphasic response in neurons of rat major pelvic ganglia. Neuroscience Letters 272(2): 119-122

Lu, L.F.; Fiscus, R.R. 1999: Interleukin-1beta causes different levels of nitric oxide-mediated depression of contractility in different positions of rat thoracic aorta. Life Sciences 64(16): 1373-1381

Siegmund, B. 2002: Interleukin-1beta converting enzyme (caspase-1) in intestinal inflammation. Biochemical Pharmacology 64(1): 1-8

Suzuki, M.; Shinohara, F.; Sato, K.; Taniguchi, T.; Takada, H.; Rikiishi, H. 2003: Interleukin-1beta converting enzyme subfamily inhibitors prevent induction of CD86 molecules by butyrate through a CREB-dependent mechanism in HL60 cells. Immunology 108(3): 375-383

Iłzecka, J.; Stelmasiak, Z.; Dobosz, B. 2001: Interleukin-1beta converting enzyme/Caspase-1 (ICE/Caspase-1) and soluble APO-1/Fas/CD 95 receptor in amyotrophic lateral sclerosis patients. Acta Neurologica Scandinavica 103(4): 255-258

Cooper, M.A.; Fehniger, T.A.; Ponnappan, A.; Mehta, V.; Wewers, M.D.; Caligiuri, M.A. 2001: Interleukin-1beta costimulates interferon-gamma production by human natural killer cells. European Journal of Immunology 31(3): 792-801

Reznikov, L.L.; Shames, B.D.; Barton, H.A.; Selzman, C.H.; Fantuzzi, G.; Kim, S.H.; Johnson, S.M.; Dinarello, C.A. 2000: Interleukin-1beta deficiency results in reduced NF-kappaB levels in pregnant mice. American Journal of Physiology. Regulatory Integrative and Comparative Physiology 278(1): R263-R270

Dil, N.; Qureshi, M.A. 2003: Interleukin-1beta does not contribute to genetic strain-based differences in iNOS expression and activity in chicken macrophages. Developmental and Comparative Immunology 27(2): 137-146

Gouze, J.N.; Bordji, K.; Gulberti, S.; Terlain, B.; Netter, P.; Magdalou, J.; Fournel-Gigleux, S.; Ouzzine, M. 2001: Interleukin-1beta down-regulates the expression of glucuronosyltransferase I, a key enzyme priming glycosaminoglycan biosynthesis: influence of glucosamine on interleukin-1beta-mediated effects in rat chondrocytes. Arthritis and Rheumatism 44(2): 351-360

Rauk, P.N.; Friebe-Hoffmann, U. 2000: Interleukin-1 beta down-regulates the oxytocin receptor in cultured uterine smooth muscle cells. American Journal of Reproductive Immunology 43(2): 85-91

Tamura, M.; Sebastian, S.; Yang, S.; Gurates, B.; Fang, Z.; Bulun, S.E. 2002: Interleukin-1beta elevates cyclooxygenase-2 protein level and enzyme activity via increasing its mRNA stability in human endometrial stromal cells: an effect mediated by extracellularly regulated kinases 1 and 2. Journal of Clinical Endocrinology and Metabolism 87(7): 3263-3273

Corwin, E.J.; Bozoky, I.; Pugh, L.C.; Johnston, N. 2003: Interleukin-1beta elevation during the postpartum period. Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine 25(1): 41-47

Viviani, B.; Bartesaghi, S.; Gardoni, F.; Vezzani, A.; Behrens, M.M.; Bartfai, T.; Binaglia, M.; Corsini, E.; Di Luca, M.; Galli, C.L.; Marinovich, M. 2003: Interleukin-1beta enhances NMDA receptor-mediated intracellular calcium increase through activation of the Src family of kinases. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 23(25): 8692-8700

Yang, C.M.; Chien, C.S.; Wang, C.C.; Hsu, Y.M.; Chiu, C.T.; Lin, C.C.; Luo, S.F.; Hsiao, L.D. 2001: Interleukin-1beta enhances bradykinin-induced phosphoinositide hydrolysis and Ca2+ mobilization in canine tracheal smooth-muscle cells: involvement of the Ras/Raf/mitogen-activated protein kinase (MAPK) kinase (MEK)/MAPK pathway. Biochemical Journal 354(Pt 2): 439-446

Manfridi, A.; Brambilla, D.; Bianchi, S.; Mariotti, M.; Opp, M.R.; Imeri, L. 2003: Interleukin-1beta enhances non-rapid eye movement sleep when microinjected into the dorsal raphe nucleus and inhibits serotonergic neurons in vitro. European Journal of Neuroscience 18(5): 1041-1049

Nikawa, T.; Ikemoto, M.; Tokuoka, K.; Teshima, S.; Alpers, D.H.; Masui, Y.; Kishi, K.; Rokutan, K. 2001: Interleukin-1beta enhances retinoic acid-mediated expression of bone-type alkaline phosphatase in rat IEC-6 cells. American Journal of Physiology. Gastrointestinal and Liver Physiology 280(3): G510-G517

Pringle, A.K.; Niyadurupola, N.; Johns, P.; Anthony, D.C.; Iannotti, F. 2001: Interleukin-1beta exacerbates hypoxia-induced neuronal damage, but attenuates toxicity produced by simulated ischaemia and excitotoxicity in rat organotypic hippocampal slice cultures. Neuroscience Letters 305(1): 29-32

Yan, G.-T.; Hao, X.-H.; Xue, H.; Wang, L.-H.; Li, Y.-L.; Shi, L.-P. 2002: Interleukin-1beta expression and phospholipase A(2) activation after intestinal ischemia/reperfusion injury. Sheng Li Xue Bao: 54(1): 28-32

Chong, J-Mun.; Sakuma, K.; Sudo, M.; Osawa, T.; Ohara, E.; Uozaki, H.; Shibahara, J.; Kuroiwa, K.; Tominaga, S-Ichi.; Hippo, Y.; Aburatani, H.; Funata, N.; Fukayama, M. 2002: Interleukin-1beta expression in human gastric carcinoma with Epstein-Barr virus infection. Journal of Virology 76(13): 6825-6831

Tsai, S.Y.; McNulty, J.A. 1999: Interleukin-1beta expression in the pineal gland of the rat. Journal of Pineal Research 27(1): 42-48

Mouihate, A.; Chen, X.; Pittman, Q.J. 1998: Interleukin-1beta fever in rats: gender difference and estrous cycle influence. American Journal of Physiology 275(5): R1450-R1454

Ritzenthaler, J.D.; Roman, J. 2001: Interleukin-1beta gene transcription in U937 cells is modulated by type i collagen and cytoskeletal integrity via distinct signaling pathways. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 21(2): 105-116

Vezzani, A.; Conti, M.; De Luigi, A.; Ravizza, T.; Moneta, D.; Marchesi, F.; De Simoni, M.G. 1999: Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 19(12): 5054-5065

Watt, J.A.; Hobbs, N.K. 2000: Interleukin-1beta immunoreactivity in identified neurons of the rat magnocellular neurosecretory system: evidence for activity-dependent release. Journal of Neuroscience Research 60(4): 478-489

Tominaga, K.; Alstergren, P.; Kurita, H.; Matsukawa, A.; Fukuda, J.; Kopp, S. 2001: Interleukin-1beta in antigen-induced arthritis of the rabbit temporomandibular joint. Archives of Oral Biology 46(6): 539-544

Goehler, L.E.; Gaykema, R.P.; Nguyen, K.T.; Lee, J.E.; Tilders, F.J.; Maier, S.F.; Watkins, L.R. 1999: Interleukin-1beta in immune cells of the abdominal vagus nerve: a link between the immune and nervous systems?. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 19(7): 2799-2806

Estevez, A.; Tognetti, T.; Rearte, B.; Sander, V.; Motta, A.B. 2002: Interleukin-1beta in the functional and structural luteolysis. Relationship with the nitric oxide system. Prostaglandins Leukotrienes and Essential Fatty Acids 67(6): 411-417

Piñero, D.J.; Hu, J.; Cook, B.M.; Scaduto, R.C.; Connor, J.R. 2000: Interleukin-1beta increases binding of the iron regulatory protein and the synthesis of ferritin by increasing the labile iron pool. Biochimica et Biophysica Acta 1497(3): 279-288

Constandil, L.; Pelissier, T.; Soto-Moyano, Rén.; Mondaca, M.; Sáez, Hán.; Laurido, C.; Muñoz, C.; López, N.; Hernández, A. 2003: Interleukin-1beta increases spinal cord wind-up activity in normal but not in monoarthritic rats. Neuroscience Letters 342(3): 139-142

Tonon, R.; D'Andrea, P. 2000: Interleukin-1beta increases the functional expression of connexin 43 in articular chondrocytes: evidence for a Ca2+-dependent mechanism. Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research 15(9): 1669-1677

Kreydiyyeh, S.I.; Al-Sadi, R. 2002: Interleukin-1beta increases urine flow rate and inhibits protein expression of Na(+)/K(+)-ATPase in the rat jejunum and kidney. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 22(10): 1041-1048

Hoozemans, J.J.; Veerhuis, R.; Janssen, I.; Rozemuller, A.J.; Eikelenboom, P. 2001: Interleukin-1beta induced cyclooxygenase 2 expression and prostaglandin E2 secretion by human neuroblastoma cells: implications for Alzheimer's disease. Experimental Gerontology 36(3): 559-570

Kim, Y.-D.; Kwon, E.-J.; Park, D.-W.; Song, S.-Y.; Yoon, S.-K.; Baek, S.-H. 2002: Interleukin-1beta induces MUC2 and MUC5AC synthesis through cyclooxygenase-2 in NCI-H292 cells. Molecular Pharmacology 62(5): 1112-1118

Kim, Y-Dae.; Jeon, J-Yun.; Woo, H.Jae.; Lee, J.Cheul.; Chung, J.Hong.; Song, S.Youn.; Yoon, S-Keun.; Baek, S-Hwan. 2002: Interleukin-1beta induces MUC2 gene expression and mucin secretion via activation of PKC-MEK/ERK, and PI3K in human airway epithelial cells. Journal of Korean Medical Science 17(6): 765-771

Castigli, E.; Arcuri, C.; Giovagnoli, L.; Luciani, R.; Giovagnoli, L.; Secca, T.; Gianfranceschi, G.L.; Bocchini, V. 2000: Interleukin-1beta induces apoptosis in GL15 glioblastoma-derived human cell line. American Journal of Physiology. Cell Physiology 279(6): C2043-C2049

Tribe, R.M.; Moriarty, P.; Dalrymple, A.; Hassoni, A.A.; Poston, L. 2003: Interleukin-1beta induces calcium transients and enhances basal and store operated calcium entry in human myometrial smooth muscle. Biology of Reproduction 68(5): 1842-1849

Franzen, R.; Pautz, A.; Bräutigam, L.; Geisslinger, G.; Pfeilschifter, J.; Huwiler, A. 2001: Interleukin-1beta induces chronic activation and de novo synthesis of neutral ceramidase in renal mesangial cells. Journal of Biological Chemistry 276(38): 35382-35389

Fan, X.M.; Wong, B.C.; Lin, M.C.; Cho, C.H.; Wang, W.P.; Kung, H.F.; Lam, S.K. 2001: Interleukin-1beta induces cyclo-oxygenase-2 expression in gastric cancer cells by the p38 and p44/42 mitogen-activated protein kinase signaling pathways. Journal of Gastroenterology and Hepatology 16(10): 1098-1104

Fiebich, B.L.; Mueksch, B.; Boehringer, M.; Hüll, M. 2000: Interleukin-1beta induces cyclooxygenase-2 and prostaglandin E(2) synthesis in human neuroblastoma cells: involvement of p38 mitogen-activated protein kinase and nuclear factor-kappaB. Journal of Neurochemistry 75(5): 2020-2028

Furumitsu, Y.; Yukioka, K.; Yukioka, M.; Ochi, T.; Morishima, Y.; Matsui-Yuasa, I.; Otani, S.; Inaba, M.; Nishizawa, Y.; Morii, H. 2000: Interleukin-1beta induces elevation of spermidine/spermine N1-acetyltransferase activity and an increase in the amount of putrescine in synovial adherent cells from patients with rheumatoid arthritis. Journal of Rheumatology 27(6): 1352-1357

Barnea, A.; Roberts, J.; Keller, P.; Word, R.A. 2001: Interleukin-1beta induces expression of neuropeptide Y in primary astrocyte cultures in a cytokine-specific manner: induction in human but not rat astrocytes. Brain Research 896(1-2): 137-145

Schmitz, T.; Leroy, M.J.; Dallot, E.; Breuiller-Fouche, M.; Ferre, F.; Cabrol, D. 2003: Interleukin-1beta induces glycosaminoglycan synthesis via the prostaglandin E2 pathway in cultured human cervical fibroblasts. Molecular Human Reproduction 9(1): 1-8

Vesey, D.A.; Cheung, C.W.Y.; Cuttle, L.; Endre, Z.A.; Gobé, G.; Johnson, D.W. 2002: Interleukin-1beta induces human proximal tubule cell injury, alpha-smooth muscle actin expression and fibronectin production. Kidney International 62(1): 31-40

Alves-Rosa, F.; Vulcano, M.; Beigier-Bompadre, M.; Fernández, G.; Palermo, M.; Isturiz, M.A. 2002: Interleukin-1beta induces in vivo tolerance to lipopolysaccharide in mice. Clinical and Experimental Immunology 128(2): 221-228

Takaoka, Y.; Niwa, S.; Nagai, H. 1999: Interleukin-1beta induces interleukin-6 production through the production of prostaglandin E(2) in human osteoblasts, MG-63 cells. Journal of Biochemistry 126(3): 553-558

Smismans, A.; Eizirik, D.L.; Pipeleers, D.G. 2000: Interleukin-1beta induces ornithine decarboxylase activity in insulin-producing cells. Cytokine 12(1): 49-54

Oger, S.ép.; Méhats, C.él.; Dallot, E.; Ferré, F.ço.; Leroy, M.-J.èp. 2002: Interleukin-1beta induces phosphodiesterase 4B2 expression in human myometrial cells through a prostaglandin E2- and cyclic adenosine 3',5'-monophosphate-dependent pathway. Journal of Clinical Endocrinology and Metabolism 87(12): 5524-5531

Inoue, A.; Ikoma, K.; Morioka, N.; Kumagai, K.; Hashimoto, T.; Hide, I.; Nakata, Y. 1999: Interleukin-1beta induces substance P release from primary afferent neurons through the cyclooxygenase-2 system. Journal of Neurochemistry 73(5): 2206-2213

Strakova, Z.; Srisuparp, S.; Fazleabas, A.T. 2000: Interleukin-1beta induces the expression of insulin-like growth factor binding protein-1 during decidualization in the primate. Endocrinology 141(12): 4664-4670

Miyachi, T.; Asai, K.; Tsuiki, H.; Mizuno, H.; Yamamoto, N.; Yokoi, T.; Aoyama, M.; Togari, H.; Wada, Y.; Miura, Y.; Kato, T. 2001: Interleukin-1beta induces the expression of lipocortin 1 mRNA in cultured rat cortical astrocytes. Neuroscience Research 40(1): 53-60

Miyamoto, N.G.; Medberry, P.S.; Hesselgesser, J.; Boehlk, S.; Nelson, P.J.; Krensky, A.M.; Perez, H.D. 2000: Interleukin-1beta induction of the chemokine RANTES promoter in the human astrocytoma line CH235 requires both constitutive and inducible transcription factors. Journal of Neuroimmunology 105(1): 78-90

Coogan, A.N.; O'Connor, J.J. 1999: Interleukin-1beta inhibits a tetraethylammonium-induced synaptic potentiation in the rat dentate gyrus in vitro. European Journal of Pharmacology 374(2): 197-206

Nathe, T.J.; Deou, J.; Walsh, B.; Bourns, B.; Clowes, A.W.; Daum, Günter. 2002: Interleukin-1beta inhibits expression of p21(WAF1/CIP1) and p27(KIP1) and enhances proliferation in response to platelet-derived growth factor-BB in smooth muscle cells. Arteriosclerosis Thrombosis and Vascular Biology 22(8): 1293-1298

Wang, S.; Cheng, Q.; Malik, S.; Yang, J. 2000: Interleukin-1beta inhibits gamma-aminobutyric acid type A (GABA(A)) receptor current in cultured hippocampal neurons. Journal of Pharmacology and Experimental Therapeutics 292(2): 497-504

Pelegrín, P.; García-Castillo, J.; Mulero, V.; Meseguer, J. 2001: Interleukin-1beta isolated from a marine fish reveals up-regulated expression in macrophages following activation with lipopolysaccharide and lymphokines. Cytokine 16(2): 67-72

Yoneda, S.; Tanihara, H.; Kido, N.; Honda, Y.; Goto, W.; Hara, H.; Miyawaki, N. 2001: Interleukin-1beta mediates ischemic injury in the rat retina. Experimental Eye Research 73(5): 661-667

Kinoshita, K.; Chatzipanteli, i.Katina.; Vitarbo, E.; Truettner, J.S.; Alonso, O.F.; Dietrich, W.Dalton. 2002: Interleukin-1beta messenger ribonucleic acid and protein levels after fluid-percussion brain injury in rats: importance of injury severity and brain temperature. Neurosurgery 51(1): 195-203; Discussion 203

Perregaux, D.G.; Labasi, J.; Laliberte, R.; Stam, E.; Solle, M.; Koller, B.; Griffiths, R.; Gabel, C.A. 2001: Interleukin-1beta posttranslational processing: Exploration of P2X7 receptor involvement. Drug Development Research 53(2-3): 83-90

White, L.R.; Leseth, K.H.; Möller, S.; Juul, R.; Adner, M.; Cappelen, J.; Bovim, G.; Aasly, J.; Edvinsson, L. 1999: Interleukin-1beta potentiates endothelin ET(B) receptor-mediated contraction in cultured segments of human temporal artery. Regulatory Peptides 81(1-3): 89-95

Orvieto, R.; Bar-Hava, I.; Schwartz, A.; Shelef, M.; Ashkenazi, J.; Bar, J.; Ben-Rafael, Z. 1999: Interleukin-1 beta production by human preimplantation embryos. Journal of Assisted Reproduction and Genetics 16(7): 394-397

Takahashi, J.L.; Giuliani, F.; Power, C.; Imai, Y.; Yong, V.W. 2003: Interleukin-1beta promotes oligodendrocyte death through glutamate excitotoxicity. Annals of Neurology 53(5): 588-595

Mason, J.L.; Suzuki, K.; Chaplin, D.D.; Matsushima, G.K. 2001: Interleukin-1beta promotes repair of the CNS. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 21(18): 7046-7052

Vasilenko, V.Y.; Petruchuk, T.A.; Gourine, V.N.; Pierau, F.K. 2000: Interleukin-1beta reduces temperature sensitivity but elevates thermal thresholds in different populations of warm-sensitive hypothalamic neurons in rat brain slices. Neuroscience Letters 292(3): 207-210

Cafferata, E.G.; González-Guerrico, A.M.; Giordano, L.; Pivetta, O.H.; Santa-Coloma, T.A. 2000: Interleukin-1beta regulates CFTR expression in human intestinal T84 cells. Biochimica et Biophysica Acta 1500(2): 241-248

Meroni, S.B.; Suburo, A.M.; Cigorraga, S.B. 2000: Interleukin-1beta regulates nitric oxide production and gamma-glutamyl transpeptidase activity in sertoli cells. Journal of Andrology 21(6): 855-861

Chen, M.C.; Paez-Espinosa, V.; Welsh, N.; Eizirik, D.L. 2000: Interleukin-1beta regulates phospholipase D-1 expression in rat pancreatic beta-cells. Endocrinology 141(8): 2822-2828

He, Q.; LaPointe, M.C. 2000: Interleukin-1beta regulates the human brain natriuretic peptide promoter via Ca(2+)-dependent protein kinase pathways. Hypertension 35(1 Part 2): 292-296

Chung, H.W.; Wen, Y.; Ahn, J.J.; Moon, H.S.; Polan, M.L. 2001: Interleukin-1beta regulates urokinase plasminogen activator (u-PA), u-PA receptor, soluble u-PA receptor, and plasminogen activator inhibitor-1 messenger ribonucleic acid expression in cultured human endometrial stromal cells. Journal of Clinical Endocrinology and Metabolism 86(3): 1332-1340

Joe, B.H.; Borke, J.L.; Keskintepe, M.; Hanes, P.J.; Mailhot, J.M.; Singh, B.B. 2001: Interleukin-1beta regulation of adhesion molecules on human gingival and periodontal ligament fibroblasts. Journal of Periodontology 72(7): 865-870

Huang, H-Yuan.; Raga, F.; Wen, Y.; Kruessel, J.S.; Soong, Y-Kuei.; Polan, M.Lake. 2003: Interleukin-1beta regulation of gonadotropin-releasing hormone messenger ribonucleic acid in cultured human endometrial stromal cells. Fertility and Sterility 79(2): 399-406

LaPointe, M.C.; Isenović, E. 1999: Interleukin-1beta regulation of inducible nitric oxide synthase and cyclooxygenase-2 involves the p42/44 and p38 MAPK signaling pathways in cardiac myocytes. Hypertension 33(1 Pt 2): 276-282

He, Q.; LaPointe, M.C. 1999: Interleukin-1beta regulation of the human brain natriuretic peptide promoter involves Ras-, Rac-, and p38 kinase-dependent pathways in cardiac myocytes. Hypertension 33(1 Pt 2): 283-289

Yang, J.; Hooper, W.Craig.; Phillips, D.J.; Talkington, D.F. 2003: Interleukin-1beta responses to Mycoplasma pneumoniae infection are cell-type specific. Microbial Pathogenesis 34(1): 17-25

Fu, L.W.; Longhurst, J.C. 1999: Interleukin-1beta sensitizes abdominal visceral afferents of cats to ischaemia and histamine. Journal of Physiology 521 Pt 1: 249-260

Pedraza, C.E.; Baltrons, M.A.; García, A. 2001: Interleukin-1beta stimulates cyclic GMP efflux in brain astrocytes. Febs Letters 507(3): 303-306

Yoshida, H.; Imaizumi, T.; Kumagai, M.; Kimura, K.; Satoh, C.; Hanada, N.; Fujimoto, K.; Nishi, N.; Tanji, K.; Matsumiya, T.; Mori, F.; Cui, X.F.; Tamo, W.; Shibata, T.; Takanashi, S.; Okumura, K.; Nakamura, T.; Wakabayashi, K.; Hirashima, M.; Sato, Y.; Satoh, K. 2001: Interleukin-1beta stimulates galectin-9 expression in human astrocytes. Neuroreport 12(17): 3755-3758

Vesey, D.A.; Cheung, C.; Cuttle, L.; Endre, Z.; Gobe, G.; Johnson, D.W. 2002: Interleukin-1beta stimulates human renal fibroblast proliferation and matrix protein production by means of a transforming growth factor-beta-dependent mechanism. Journal of Laboratory and Clinical Medicine 140(5): 342-350

Guo, C-Jiang.; Douglas, S.D.; Lai, J-Ping.; Pleasure, D.E.; Li, Y.; Williams, M.; Bannerman, P.; Song, L.; Ho, W-Zhe. 2003: Interleukin-1beta stimulates macrophage inflammatory protein-1alpha and -1beta expression in human neuronal cells (NT2-N). Journal of Neurochemistry 84(5): 997-1005

Ikoma, Y.; Nomura, S.; Ito, T.; Katsumata, Y.; Nakata, M.; Iwanaga, K.; Okada, M.; Kikkawa, F.; Tamakoshi, K.; Nagasaka, T.; Tsujimoto, M.; Mizutani, S. 2003: Interleukin-1beta stimulates placental leucine aminopeptidase/oxytocinase expression in BeWo choriocarcinoma cells. Molecular Human Reproduction 9(2): 103-110

Tokukoda, Y.; Takata, S.; Kaji, H.; Kitazawa, R.; Sugimoto, T.; Chihara, K. 2001: Interleukin-1beta stimulates transendothelial mobilization of human peripheral blood mononuclear cells with a potential to differentiate into osteoclasts in the presence of osteoblasts. Endocrine Journal 48(4): 443-452

Major, C.D.; Wolf, B.A. 2001: Interleukin-1beta stimulation of c-Jun NH(2)-terminal kinase activity in insulin-secreting cells: evidence for cytoplasmic restriction. Diabetes 50(12): 2721-2728

Denson, L.A.; Auld, K.L.; Schiek, D.S.; McClure, M.H.; Mangelsdorf, D.J.; Karpen, S.J. 2000: Interleukin-1beta suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation. Journal of Biological Chemistry 275(12): 8835-8843

Li, L.-X.; Yoshikawa, H.; Egeberg, K.W.; Grill, V. 2003: Interleukin-1beta swiftly down-regulates UCP-2 mRNA in beta-cells by mechanisms not directly coupled to toxicity. Cytokine 23(4-5): 101-107

Rempel, H.; Kusdra, L.; Pulliam, L. 2001: Interleukin-1beta up-regulates expression of neurofilament light in human neuronal cells. Journal of Neurochemistry 78(3): 640-645

Rao, V.H.; Singh, R.K.; Delimont, D.C.; Schaefer, G.B.; Bridge, J.A.; Neff, J.R.; Sanger, W.G.; Sappenfield, J.W.; Buehler, B.A.; Finnell, R.H. 1999: Interleukin-1beta upregulates MMP-9 expression in stromal cells of human giant cell tumor of bone. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 19(10): 1207-1217

Tsai, J.A.; Rong, H.; Torring, O.; Matsushita, H.; Bucht, E. 2000: Interleukin-1beta upregulates PTHrP-mRNA expression and protein production and decreases TGF-beta in normal human osteoblast-like cells. Calcified Tissue International 66(5): 363-369

Gröne, A.; Alldinger, S.; Baumgärtner, W. 2000: Interleukin-1beta, -6, -12 and tumor necrosis factor-alpha expression in brains of dogs with canine distemper virus infection. Journal of Neuroimmunology 110(1-2): 20-30

Gui, Y.; Zheng, X.L.; Hollenberg, M.D. 2000: Interleukin-1beta, Src- and non-Src tyrosine kinases, and nitric oxide synthase induction in rat aorta in vitro. American Journal of Physiology. Heart and Circulatory Physiology 279(2): H566-H576

Hou, L-Tuan.; Liu, C-Meei.; Liu, B-Yuan.; Lin, S-Jung.; Liao, C-Shih.; Rossomando, E.F. 2003: Interleukin-1beta, clinical parameters and matched cellular-histopathologic changes of biopsied gingival tissue from periodontitis patients. Journal of Periodontal Research 38(3): 247-254

Hartlage-Rübsamen, M.; Lemke, R.; Schliebs, R. 1999: Interleukin-1beta, inducible nitric oxide synthase, and nuclear factor-kappaB are induced in morphologically distinct microglia after rat hippocampal lipopolysaccharide/interferon-gamma injection. Journal of Neuroscience Research 57(3): 388-398

Haspolat, S.; Anlar, B.; Köse, G.; Coskun, M.; Yegin, O. 2001: Interleukin-1beta, interleukin-1 receptor antagonist levels in patients with subacute sclerosing panencephalitis and the effects of different treatment protocols. Journal of Child Neurology 16(6): 417-420

Cantagrel, A.; Navaux, F.; Loubet-Lescoulié, P.; Nourhashemi, F.; Enault, G.; Abbal, M.; Constantin, A.; Laroche, M.; Mazières, B. 1999: Interleukin-1beta, interleukin-1 receptor antagonist, interleukin-4, and interleukin-10 gene polymorphisms: relationship to occurrence and severity of rheumatoid arthritis. Arthritis and Rheumatism 42(6): 1093-1100

Bleau, A-Marie.; Maurel, P.; Pichette, V.; Leblond, Fçois.; du Souich, P. 2003: Interleukin-1beta, interleukin-6, tumour necrosis factor-alpha and interferon-gamma released by a viral infection and an aseptic inflammation reduce CYP1A1, 1A2 and 3A6 expression in rabbit hepatocytes. European Journal of Pharmacology 473(2-3): 197-206

Chien, H.H.; Lin, W.L.; Cho, M.I. 1999: Interleukin-1beta-induced release of matrix proteins into culture media causes inhibition of mineralization of nodules formed by periodontal ligament cells in vitro. Calcified Tissue International 64(5): 402-413

Saha, N.; Moldovan, F.; Tardif, G.; Pelletier, J.P.; Cloutier, J.M.; Martel-Pelletier, J. 1999: Interleukin-1beta-converting enzyme/caspase-1 in human osteoarthritic tissues: localization and role in the maturation of interleukin-1beta and interleukin-18. Arthritis and Rheumatism 42(8): 1577-1587

Loscher, C.E.; Donnelly, S.; Mills, K.H.; Lynch, M.A. 2000: Interleukin-1beta-dependent changes in the hippocampus following parenteral immunization with a whole cell pertussis vaccine. Journal of Neuroimmunology 111(1-2): 68-76

Wu, Z.-X.; Satterfield, B.E.; Fedan, J.S.; Dey, R.D. 2002: Interleukin-1beta-induced airway hyperresponsiveness enhances substance P in intrinsic neurons of ferret airway. American Journal of Physiology. Lung Cellular and Molecular Physiology 283(5): L909-L917

Ling, Z.; Van de Casteele, M.; Eizirik, D.L.; Pipeleers, D.G. 2000: Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis. Diabetes 49(3): 340-345

Yang, C.-M.; Chien, C.-S.; Hsiao, L.-D.; Luo, S.-F.; Wang, C.-C. 2002: Interleukin-1beta-induced cyclooxygenase-2 expression is mediated through activation of p42/44 and p38 MAPKS, and NF-kappaB pathways in canine tracheal smooth muscle cells. Cellular Signalling 14(11): 899-911

Guan, Z.; Buckman, S.Y.; Miller, B.W.; Springer, L.D.; Morrison, A.R. 1998: Interleukin-1beta-induced cyclooxygenase-2 expression requires activation of both c-Jun NH2-terminal kinase and p38 MAPK signal pathways in rat renal mesangial cells. Journal of Biological Chemistry 273(44): 28670-28676

Fewell, J.E.; Wong, V.H. 2002: Interleukin-1beta-induced fever does not alter the ability of 5- to 6-day-old rat pups to autoresuscitate from hypoxia-induced apnoea. Experimental Physiology 87(1): 17-24

Plata-Salamán, C.R.; Peloso, E.; Satinoff, E. 1998: Interleukin-1beta-induced fever in young and old Long-Evans rats. American Journal of Physiology 275(5): R1633-R1638

Wang, M.; Murakami, Y.; Okada, S.; Yokotani, K. 2002: Interleukin-1beta-induced increases of plasma catecholamine levels in rats: enhancement by superior cervical ganglionectomy. Pharmacology 65(3): 136-140

Stickings, P.; Cunningham, J.M. 2002: Interleukin-1beta-induced nitric oxide production and inhibition of insulin secretion in rat islets of langerhans is dependent upon the nitric oxide synthase cofactor tetrahidrobiopterin. Cytokine 18(2): 81-85

Xu, R.; Morales, J.A.; Muniyappa, R.; Skafar, D.F.; Ram, J.L.; Sowers, J.R. 1999: Interleukin-1beta-induced nitric oxide production in rat aortic endothelial cells: Inhibition by estradiol in normal and high glucose cultures. Life Sciences 64(26): 2451-2462

Kähönen, M.; Wu, X.; Schini-Kerth, V.B.; Ylikotila, O.; Arvola, P.; Tolvanen, J.P.; Moilanen, E.; Pörsti, I. 1999: Interleukin-1beta-induced nitric oxide synthesis in aortic rings from normal and hyperinsulinaemic rats: effect of physical exercise. Naunyn-Schmiedeberg's Archives of Pharmacology 360(1): 63-68

Maliner Stratton, M.S.; Klein, R.D.; Udayakumar, T.S.; Nagle, R.B.; Bowden, G.T. 2001: Interleukin-1beta-induced promatrilysin expression is mediated by NFkappaB-regulated synthesis of interleukin-6 in the prostate carcinoma cell line, LNCaP. Neoplasia (New York) 3(6): 509-520

Hertelendy, F.; Rastogi, P.; Molnár, M.; Romero, R. 2001: Interleukin-1beta-induced prostaglandin E2 production in human myometrial cells: role of a pertussis toxin-sensitive component. American Journal of Reproductive Immunology 45(3): 142-147

Morioka, N.; Takeda, K.; Kumagai, K.; Hanada, T.; Ikoma, K.; Hide, I.; Inoue, A.; Nakata, Y. 2002: Interleukin-1beta-induced substance P release from rat cultured primary afferent neurons driven by two phospholipase A2 enzymes: secretory type IIA and cytosolic type IV. Journal of Neurochemistry 80(6): 989-997

Schwemmer, M.; Aho, H.; Michel, J.B. 2001: Interleukin-1beta-induced type IIA secreted phospholipase A2 gene expression and extracellular activity in rat vascular endothelial cells. Tissue and Cell 33(3): 233-240

Velthuis, J.H.L.; de Bont, H.J.G.M.; Medema, J.-P.; Kuppen, P.J.K.; Mulder, G.J.; Nagelkerke, J.F. 2003: Interleukin-2 activated NK cells do not use the CD95L- and TRAIL-pathways in the rapid induction of apoptosis of rat colon carcinoma CC531s cells. Immunobiology 207(2): 115-127

Hoenstein, R.; Admon, D.; Solomon, A.; Norris, A.; Moqbel, R.; Levi-Schaffer, F. 2001: Interleukin-2 activates human peripheral blood eosinophils. Cellular Immunology 210(2): 116-124

Hájek, R.; Korístek, Z.; Vinklárková, J.; Janovská, E.; Klabusay, M.; Doubek, M.; Dvoráková, D.; Bourková, L.; Dusek, L.; Büchler, T.; Adler, J.; Adam, Z.; Penka, M.; Mayer, J.; Vorlícek, J. 2002: Interleukin-2 activation of haematopoietic stem cells. Acta Medica Austriaca 29(2): 61-67

Zalcman, S.; Murray, L.; Dyck, D.G.; Greenberg, A.H.; Nance, D.M. 1998: Interleukin-2 and -6 induce behavioral-activating effects in mice. Brain Research 811(1-2): 111-121

Recchia, F.; De Filippis, S.; Rosselli, M.; Saggio, G.; Fumagalli, L.; Rea, S. 2002: Interleukin-2 and 13-cis retinoic acid in the treatment of minimal residual disease: a phase Ii study. International Journal of Oncology 20(6): 1275-1282

Alileche, A. 2003: Interleukin-2 and cancer: Critical analysis of results, problems and expectations. Medical Hypotheses 60(2): 202-208

Bubeník, J.; Mikysková, R.; Vonka, Vír.; Mendoza, L.; Símová, J.; Smahel, M.; Indrová, M. 2003: Interleukin-2 and dendritic cells as adjuvants for surgical therapy of tumours associated with human papillomavirus type 16. Vaccine 21(9-10): 891-896

Johansson, M.; Henriksson, R.; Bergenheim, A.T.; Koskinen, L.O. 2000: Interleukin-2 and histamine in combination inhibit tumour growth and angiogenesis in malignant glioma. British Journal of Cancer 83(6): 826-832

Zand, M.S.; Li, Y.; Hancock, W.; Li, X.C.; Roy-Chaudhury, P.; Zheng, X.X.; Strom, T.B. 2000: Interleukin-2 and interferon-gamma double knockout mice reject heterotopic cardiac allografts. Transplantation 70(9): 1378-1381

Sholl-Franco, A.; Figueiredo, K.G.; de Araujo, E.G. 2001: Interleukin-2 and interleukin-4 increase the survival of retinal ganglion cells in culture. Neuroreport 12(1): 109-112

Okuno, K.; Hirai, N.; Takemoto, Y.; Kawai, I.; Yasutomi, M. 2000: Interleukin-2 as a modulator of 5-fluorouracil in hepatic arterial immunochemotherapy for liver metastases. Hepato-Gastroenterology 47(32): 487-491

Esteban, E.; Puertas, J.; Fra, J.; Estrada, E.; Vietiez, J.M.; Fernandez, J.L.; Sala, M.; Carrasco, J.; Buesa, J.M.; Lacave, A.J. 2001: Interleukin-2 based home therapy in advanced renal cell cancer (ARCC). Oncologia 24(1): 33-36

Wagner, J.R.; Walther, M.M.; Linehan, W.M.; White, D.E.; Rosenberg, S.A.; Yang, J.C. 1999: Interleukin-2 based immunotherapy for metastatic renal cell carcinoma with the kidney in place. Journal of Urology 162(1): 43-45

Ravindranath, M.H.; Gonzales, A.; Soh, D.; Nishimoto, K.; Tam, W.Y.; Bilchik, A.; Morton, D.L.; O'Day, S. 2001: Interleukin-2 binds to ganglioside GD(1b). Biochemical and Biophysical Research Communications 283(2): 369-373

Fukushima, K.; Yamashita, K. 2001: Interleukin-2 carbohydrate recognition modulates CTLL-2 cell proliferation. Journal of Biological Chemistry 276(10): 7351-7356

Jones, D.R.; Pettitt, T.R.; Sanjuán, M.A.; Mérida, I.; Wakelam, M.J. 1999: Interleukin-2 causes an increase in saturated/monounsaturated phosphatidic acid derived from 1,2-diacylglycerol and 1-O-alkyl-2-acylglycerol. Journal of Biological Chemistry 274(24): 16846-16852

Hilton, L.S.; Bean, A.G.D.; Kimpton, W.G.; Lowenthal, J.W. 2002: Interleukin-2 directly induces activation and proliferation of chicken T cells in vivo. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 22(7): 755-763

García-Vázquez, M.D.; Boyano, M.D.; Cañavate, M.L.; Gardeazabal, J.; de Galdeano, A.G.; López-Michelena, T.; Ratón, J.A.; Izu, R.; Díaz-Ramón, J.L.; Díaz-Pérez, J.L. 2000: Interleukin-2 enhances the growth of human melanoma cells derived form primary but not from metastatic tumours. European Cytokine Network 11(4): 654-661

Carson, W.E.; Parihar, R.; Lindemann, M.J.; Personeni, N.; Dierksheide, J.; Meropol, N.J.; Baselga, J.; Caligiuri, M.A. 2001: Interleukin-2 enhances the natural killer cell response to Herceptin-coated Her2/neu-positive breast cancer cells. European Journal of Immunology 31(10): 3016-3025

Wang, K.S.; Frank, D.A.; Ritz, J. 2000: Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4. Blood 95(10): 3183-3190

Bouet-Toussaint, F.; Genetel, N.; Rioux-Leclercq, N.; Bansard, J.Y.; Levêque, J.; Guillé, F.; Patard, J.J.; Lesimple, T.; Catros-Quemener, V. 2000: Interleukin-2 expanded lymphocytes from lymph node and tumor biopsies of human renal cell carcinoma, breast and ovarian cancer. European Cytokine Network 11(2): 217-224

Saparov, A.; Wagner, F.H.; Zheng, R.; Oliver, J.R.; Maeda, H.; Hockett, R.D.; Weaver, C.T. 1999: Interleukin-2 expression by a subpopulation of primary T cells is linked to enhanced memory/effector function. Immunity 11(3): 271-280

Nagy, Z.S.; Wang, Y.; Erwin-Cohen, R.A.; Aradi, J.án.; Monia, B.; Wang, L.H.; Stepkowski, S.M.; Rui, H.; Kirken, R.A. 2002: Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways. Journal of Leukocyte Biology 72(4): 819-828

Kim, E.J.; Cho, D.; Hwang, S.Y.; Kim, T.S. 2001: Interleukin-2 fusion protein with anti-CD3 single-chain Fv (sFv) selectively protects T cells from dexamethasone-induced apoptosis. Vaccine 20(3-4): 608-615

Petitto, J.M.; Streit, W.J.; Huang, Z.; Butfiloski, E.; Schiffenbauer, J. 2000: Interleukin-2 gene deletion produces a robust reduction in susceptibility to experimental autoimmune encephalomyelitis in C57BL/6 mice. Neuroscience Letters 285(1): 66-70

Yao, M-Zhong.; Wang, J-Hui.; Gu, J-Fa.; Sun, L-Ying.; Liu, H.; Zhao, Z-Qi.; Liu, X-Yuan. 2002: Interleukin-2 gene has superior antinociceptive effects when delivered intrathecally. Neuroreport 13(6): 791-794

Yao, M-Z.; Gu, J-F.; Wang, J-H.; Sun, L-Y.; Lang, M-F.; Liu, J.; Zhao, Z-Q.; Liu, X-Y. 2002: Interleukin-2 gene therapy of chronic neuropathic pain. Neuroscience 112(2): 409-416

Dix, R.D.; Cousins, S.W. 2003: Interleukin-2 immunotherapy of murine cytomegalovirus retinitis during MAIDS correlates with increased intraocular CD8+ T-cell infiltration. Ophthalmic Research 35(3): 154-159

Kadhim, H.; Tabarki, B.; De Prez, C.; Rona, A-M.; Sébire, G. 2002: Interleukin-2 in the pathogenesis of perinatal white matter damage. Neurology 58(7): 1125-1128

Valdez, H.; Mitsuyasu, R.; Landay, A.; Sevin, A.D.; Chan, E.S.; Spritzler, J.; Kalams, S.A.; Pollard, R.B.; Fahey, J.; Fox, L.; Namkung, A.; Estep, S.; Moss, R.; Sahner, D.; Lederman, M.M. 2003: Interleukin-2 Increases CD4+ lymphocyte numbers but does not enhance responses to immunization: results of A5046s. Journal of Infectious Diseases 187(2): 320-325

Cao, C.-M.; Xia, Q.; Bruce, I.C.; Zhang, X.; Fu, C.; Chen, J.-Z. 2003: Interleukin-2 increases activity of sarcoplasmic reticulum Ca2+-ATPase, but decreases its sensitivity to calcium in rat cardiomyocytes. Journal of Pharmacology and Experimental Therapeutics 306(2): 572-580

Cao, C.-M.; Ye, S.; Yu, H.; Xu, Q.-S.; Ye, Z.-G.; Shen, Y.-L.; Lu, Y.; Xia, Q. 2003: Interleukin-2 induced endothelium-dependent relaxation of rat thoracic aorta. Sheng Li Xue Bao: 55(1): 19-23

Kovacs, J.A.; Vogel, S.; Metcalf, J.A.; Baseler, M.; Stevens, R.; Adelsberger, J.; Lempicki, R.; Hengel, R.L.; Sereti, I.; Lambert, L.; Dewar, R.L.; Davey, R.T.; Walker, R.E.; Falloon, J.; Polis, M.A.; Masur, H.; Lane, H.C. 2001: Interleukin-2 induced immune effects in human immunodeficiency virus-infected patients receiving intermittent interleukin-2 immunotherapy. European Journal of Immunology 31(5): 1351-1360

Porta, C.; Danova, M.; Orengo, A.M.; Ferrini, S.; Moroni, M.; Gaggero, A.; Libener, R.; Betta, P.G.; Ferrari, S.; Procopio, A.; Strizzi, L.; Mutti, L. 2000: Interleukin-2 induces cell cycle perturbations leading to cell growth inhibition and death in malignant mesothelioma cells in vitro. Journal of Cellular Physiology 185(1): 126-134

Cao-Chun-Mei; Xia-Qiang; Shen-Yue-Liang; Chen-Ying-Ying; Xu-Wan-Hong 2001: Interleukin-2 inhibited contractility of isolated ventricular myocytes via cardiac kappa-opioid receptor pathway. Zhongguo Yaolixue Yu Dulixue Zazhi 15(4): 266-271

Lampinen, M.; Håkansson, L.; Venge, P. 2001: Interleukin-2 inhibits eosinophil migration but is counteracted by IL-5 priming. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology 31(2): 249-258

Biola, A.; Lefebvre, P.; Perrin-Wolff, M.; Sturm, M.; Bertoglio, J.; Pallardy, M. 2001: Interleukin-2 inhibits glucocorticoid receptor transcriptional activity through a mechanism involving STAT5 (signal transducer and activator of transcription 5) but not AP-1. Molecular Endocrinology 15(7): 1062-1076

Casana, P.H.; Hernandez, H.; Arana, M.J. 2002: Interleukin-2 inhibits proliferation of HPV-associated tumor cells and halts tumor growth in vivo. Biochemical and Biophysical Research Communications 299(5): 818-824

Kanda, Y.; Jikihara, H.; Markoff, E.; Handwerger, S. 1999: Interleukin-2 inhibits the synthesis and release of prolactin from human decidual cells. Journal of Clinical Endocrinology and Metabolism 84(2): 677-681

Ten, R.M.; Anderson, P.M.; Zein, N.N.; Temesgen, Z.; Clawson, M.Lou.; Weiss, W. 2002: Interleukin-2 liposomes for primary immune deficiency using the aerosol route. International Immunopharmacology 2(2-3): 333-344

Plebani, A.; Ciravegna, B.; Ponte, M.; Mingari, M.C.; Moretta, L. 2000: Interleukin-2 mediated restoration of natural killer cell function in a patient with Griscelli syndrome. European Journal of Pediatrics 159(9): 713-714

Ye, J.H.; Tao, L.; Zalcman, S.S. 2001: Interleukin-2 modulates N-methyl-D-aspartate receptors of native mesolimbic neurons. Brain Research 894(2): 241-248

Tinel, M.; Elkahwaji, J.; Robin, M.A.; Fardel, N.; Descatoire, V.; Haouzi, D.; Berson, A.; Pessayre, D. 1999: Interleukin-2 overexpresses c-myc and down-regulates cytochrome P-450 in rat hepatocytes. Journal of Pharmacology and Experimental Therapeutics 289(2): 649-655

Paciucci, P.A.; Ryder, J.S.; Mandell, J.P.; Morris, J.C.; Holland, J.F. 2000: Interleukin-2 plus chemotherapy for patients with metastatic melanoma. Melanoma Research 10(3): 291-295

Zalcman, S.S. 2001: Interleukin-2 potentiates novelty- and GBR 12909-induced exploratory activity. Brain Research 899(1-2): 1-9

Simon, H.-U.; Plötz, S.; Simon, D.; Seitzer, U.; Braathen, L.R.; Menz, G.ün.; Straumann, A.; Dummer, R.; Levi-Schaffer, F. 2003: Interleukin-2 primes eosinophil degranulation in hypereosinophilia and Wells' syndrome. European Journal of Immunology 33(4): 834-839

Utsugisawa, K.; Nagane, Y.; Obara, D.; Kondoh, R.; Yonezawa, H.; Tohgi, H. 2003: Interleukin-2 production by peripheral blood mononuclear cells from patients with myasthenia gravis. European Neurology 49(3): 160-163

Orvieto, R.; Leites, T.; Abir, R.; Bar, J.; Yoeli, R.; Feldberg, D.; Fisch, B. 2003: Interleukin-2 production in whole blood cell cultures of women undergoing controlled ovarian hyperstimulation for assisted reproduction technology cycles. American Journal of Reproductive Immunology 50(3): 220-223

Norris, M.S.; McConnell, T.J.; Mannie, M.D. 2001: Interleukin-2 promotes antigenic reactivity of rested T cells but prolongs the postactivational refractory phase of activated T cells. Cellular Immunology 211(1): 51-60

Strehlau, J.; Pape, L.; Offner, G.; Nashan, B.; Ehrich, J.H. 2000: Interleukin-2 receptor antibody-induced alterations of ciclosporin dose requirements in paediatric transplant recipients. Lancet 356(9238): 1327-1328

Nishiyama, R.; Sakaguchi, T.; Kinugasa, T.; Gu, X.; MacDermott, R.P.; Podolsky, D.K.; Reinecker, H.C. 2001: Interleukin-2 receptor beta subunit-dependent and -independent regulation of intestinal epithelial tight junctions. Journal of Biological Chemistry 276(38): 35571-35580

Lietz, K.; John, R.; Beniaminovitz, A.; Burke, E.M.; Suciu-Foca, N.; Mancini, D.M.; Edwards, N.M.; Itescu, S. 2003: Interleukin-2 receptor blockade in cardiac transplantation: influence of HLA-DR locus incompatibility on treatment efficacy. Transplantation 75(6): 781-787

MacLean, M.A.; Wilson, R.; Jenkins, C.; Miller, H.; Walker, J.J. 2002: Interleukin-2 receptor concentrations in pregnant women with a history of recurrent miscarriage. Human Reproduction 17(1): 219-220

Adu, D.; Cockwell, P.; Ives, N.J.; Shaw, J.; Wheatley, K. 2003: Interleukin-2 receptor monoclonal antibodies in renal transplantation: meta-analysis of randomised trials. Bmj 326(7393): 789

Zhu, L.; Wang, P.; Luo, Y.; Lu, N.; Wang, H. 1999: Interleukin-2 receptoralpha gene expression in intestinal allograft rejection. Microsurgery 19(7): 311-313

Vulcano, M.; Galassi, N.; Felippo, M.; Vernava, D.; Olabuenaga, S. 1999: Interleukin-2 restores natural killer activity inhibited by sera from HIV+ hemophilic patients. Medicina 59(2): 162-166

Albright, A.V.; Frank, I.; González-Scarano, F. 1999: Interleukin-2 treatment of microglia has no effect on in vitro HIV infection. Aids 13(4): 527-528

Weissman, D.; Dybul, M.; Daucher, M.B.; Davey, R.T.; Walker, R.E.; Kovacs, J.A. 2000: Interleukin-2 up-regulates expression of the human immunodeficiency virus fusion coreceptor CCR5 by CD4+ lymphocytes in vivo. Journal of Infectious Diseases 181(3): 933-938

Boccardo, F.; Rubagotti, A.; Canobbio, L.; Galligioni, E.; Sorio, R.; Lucenti, A.; Cognetti, F.; Ruggeri, E.; Landonio, G.; Baiocchi, C.; Besana, C.; Citterio, G.; De Rosa, M.; Calabresi, F. 1998: Interleukin-2, interferon-alpha and interleukin-2 plus interferon-alpha in renal cell carcinoma. A randomized phase II trial. Tumori 84(5): 534-539

Gez, E.; Rubinov, R.; Gaitini, D.; Meretyk, S.; Best, L-Anson.; Native, O.; Stein, A.; Erlich, N.; Beny, A.; Zidan, J.; Haim, N.; Kuten, A. 2002: Interleukin-2, interferon-alpha, 5-fluorouracil, and vinblastine in the treatment of metastatic renal cell carcinoma: a prospective phase II study: the experience of Rambam and Lin Medical Centers 1996-2000. Cancer 95(8): 1644-1649

Blom, W.M.; De Bont, H.J.; Meijerman, I.; Kuppen, P.J.; Mulder, G.J.; Nagelkerke, J.F. 1999: Interleukin-2-activated natural killer cells can induce both apoptosis and necrosis in rat hepatocytes. Hepatology 29(3): 785-792

Cifone, M.G.; D'Alò, S.; Parroni, R.; Millimaggi, D.; Biordi, L.; Martinotti, S.; Santoni, A. 1999: Interleukin-2-activated rat natural killer cells express inducible nitric oxide synthase that contributes to cytotoxic function and interferon-gamma production. Blood 93(11): 3876-3884

Sullivan, A.K.; Hardy, G.A.; Nelson, M.R.; Gotch, F.; Gazzard, B.G.; Imami, N. 2003: Interleukin-2-associated viral breakthroughs induce HIV-1-specific CD4 T cell responses in patients on fully suppressive highly active antiretroviral therapy. Aids 17(4): 628-629

Hayashi, M.; Tomita, M.; Yoshizato, K. 2002: Interleukin-2-collagen chimeric protein which liberates interleukin-2 upon collagenolysis. Protein Engineering 15(5): 429-436

Garrelds, I.M.; Van Meeteren, M.E.; Meijssen, M.A.C.; Zijlstra, F.J. 2002: Interleukin-2-deficient mice: Effect on cytokines and inflammatory cells in chronic colonic disease. Digestive Diseases and Sciences 47(3): 503-510

Hamar, P.; Peti-Peterdi, J.; Szabó, A.; Becker, G.; Flach, R.; Rosivall, L.; Heemann, U. 2001: Interleukin-2-dependent mechanisms are involved in the development of glomerulosclerosis after partial renal ablation in rats. Experimental Nephrology 9(2): 133-141

Liu, K.; Rosenberg, S.A. 2003: Interleukin-2-independent proliferation of human melanoma-reactive T lymphocytes transduced with an exogenous IL-2 gene is stimulation dependent. Journal of ImmunoTherapy 26(3): 190-201

Song, P.; Liu, X-Yuan.; Zhao, Z-Qi. 2002: Interleukin-2-induced antinociception in morphine-insensitive rats. Acta Pharmacologica Sinica 23(11): 981-984

Nag, S.; Lamkhioued, B.; Renzi, P.M. 2002: Interleukin-2-induced increased airway responsiveness and lung Th2 cytokine expression occur after antigen challenge through the leukotriene pathway. American Journal of Respiratory and Critical Care Medicine 165(11): 1540-1545

Zalcman, S.S. 2002: Interleukin-2-induced increases in climbing behavior: Inhibition by dopamine D-1 and D-2 receptor antagonists. Brain Research 944(1-2): 157-164

Jyothi, M.D.; Khar, A. 2000: Interleukin-2-induced nitric oxide synthase and nuclear factor-kappaB activity in activated natural killer cells and the production of interferon-gamma. Scandinavian Journal of Immunology 52(2): 148-155

Engin, Hüseyin.; Oksüzoğlu, C.Berna.; Altundağ, K. 2002: Interleukin-2-induced reversible hyperbilirubinemia and cholestasis in a patient with Gilbert's syndrome. Journal of Gastroenterology 37(2): 145-146

Boni, L.T.; Batenjany, M.M.; Neville, M.E.; Guo, Y.; Xu, L.; Wu, F.; Mason, J.T.; Robb, R.J.; Popescu, M.C. 2001: Interleukin-2-induced small unilamellar vesicle coalescence. Biochimica et Biophysica Acta 1514(1): 127-138

Aarnoudse, C.A.; Van Den Doel, P.B.; Heemskerk, B.; Schrier, P.I. 1999: Interleukin-2-induced, melanoma-specific T cells recognize CAMEL, an unexpected translation product of LAGE-1. International Journal of Cancer 82(3): 442-448

Weston, L.E.; Sullivan, J.S.; Keogh, A.M.; Geczy, A.F. 2000: Interleukin-2-producing helper T lymphocyte precursor frequency and rejection: a longitudinal cellular study after cardiac transplantation. Immunology and Cell Biology 78(3): 272-279

Cordel, S.; Dupas, B.; Douillard, J.Y.; Meflah, K. 1998: Interleukin-2/sodium butyrate treatment cures rats bearing liver tumors after acquired 5-fluorouracil resistance. International Journal of Cancer 78(6): 735-739

Parrish-Novak, J.; Foster, D.C.; Holly, R.D.; Clegg, C.H. 2002: Interleukin-21 and the IL-21 receptor: novel effectors of NK and T cell responses. Journal of Leukocyte Biology 72(5): 856-863

Brenne, A-Tove.; Ro, T.Baade.; Waage, A.; Sundan, A.; Borset, M.; Hjorth-Hansen, H. 2002: Interleukin-21 is a growth and survival factor for human myeloma cells. Blood 99(10): 3756-3762

Lejeune, D.; Dumoutier, L.; Constantinescu, S.; Kruijer, W.; Schuringa, J.Jacob.; Renauld, J-Christophe. 2002: Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10. Journal of Biological Chemistry 277(37): 33676-33682

Aggarwal, S.; Ghilardi, N.; Xie, M.-H.; de Sauvage, F.J.; Gurney, A.L. 2003: Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. Journal of Biological Chemistry 278(3): 1910-1914

Lotze, M.T.; Shurin, M.; Esche, C.; Tahara, H.; Storkus, W.; Kirkwood, J.M.; Whiteside, T.L.; Elder, E.M.; Okada, H.; Robbins, P. 2000: Interleukin-2: developing additional cytokine gene therapies using fibroblasts or dendritic cells to enhance tumor immunity. Cancer Journal from Scientific American 6(Suppl): S61-S66

Jiang, C.L.; Xu, D.; Lu, C.L.; Wang, Y.X.; You, Z.D.; Liu, X.Y. 2000: Interleukin-2: structural and biological relatedness to opioid peptides. Neuroimmunomodulation 8(1): 20-24

Storozynsky, E.; Woodward, J.G.; Frelinger, J.G.; Lord, E.M. 1999: Interleukin-3 and granulocyte-macrophage colony-stimulating factor enhance the generation and function of dendritic cells. Immunology 97(1): 138-149

Di Simone, N.; Caliandro, D.; Castellani, R.; Ferrazzani, S.; Caruso, A. 2000: Interleukin-3 and human trophoblast: In vitro explanations for the effect of interleukin in patients with antiphospholipid antibody syndrome. Fertility and Sterility 73(6): 1194-1200

Buelens, C.; Bartholomé, E.J.; Amraoui, Z.; Boutriaux, M.; Salmon, I.; Thielemans, K.; Willems, F.; Goldman, M. 2002: Interleukin-3 and interferon beta cooperate to induce differentiation of monocytes into dendritic cells with potent helper T-cell stimulatory properties. Blood 99(3): 993-998

Galanakis, E.; Makis, A.; Bourantas, K.L.; Papadopoulou, Z.L. 2002: Interleukin-3 and interleukin-4 in childhood brucellosis. Infection 30(1): 33-34

Michl, P.; Beikler, T.; Engelhardt, D.; Weber, M.M. 2000: Interleukin-3 and interleukin-6 stimulate bovine adrenal cortisol secretion through different pathways. Journal of Neuroendocrinology 12(1): 23-28

Itakura, A.; Miura, Y.; Hikasa, Y.; Kiso, Y.; Matsuda, H. 2001: Interleukin-3 and stem cell factor modulate cell cycle regulatory factors in mast cells: Negative regulation of p27Kip1 in proliferation of mast cells induced by interleukin-3 but not stem cell factor. Experimental Hematology 29(7): 803-811

Bessler, H.; Bergman, M.; Salman, H. 2000: Interleukin-3 and stress. Biomedicine and PharmacoTherapy 54(6): 299-304

Mangi, M.H.; Newland, A.C. 1999: Interleukin-3 in hematology and oncology: current state of knowledge and future directions. Cytokines Cellular and Molecular Therapy 5(2): 87-95

Poommipanit, P.B.; Chen, B.; Oltvai, Z.N. 1999: Interleukin-3 induces the phosphorylation of a distinct fraction of bcl-2. Journal of Biological Chemistry 274(2): 1033-1039

Kim, H.M.; Ko, S.G.; Kim, J.J.; Chung, Y.T.; An, N.H. 1999: Interleukin-3 or immunoglobulin E promotes expression of protein kinase C delta gene in murine mast cells. Pharmacological Research 40(2): 147-151

Ishizuka, T.; Okayama, Y.; Kobayashi, H.; Mori, M. 1999: Interleukin-3 production by mast cells from human lung. Inflammation 23(1): 25-35

Nitsche, A.; Junghahn, I.; Thulke, S.; Aumann, J.; Radonić, A.; Fichtner, I.; Siegert, W. 2003: Interleukin-3 promotes proliferation and differentiation of human hematopoietic stem cells but reduces their repopulation potential in NOD/SCID mice. Stem Cells 21(2): 236-244

Muñoz, L.; Nomdedéu, J.F.; López, O.; Carnicer, M.J.; Bellido, M.; Aventín, A.; Brunet, S.; Sierra, J. 2001: Interleukin-3 receptor alpha chain (CD123) is widely expressed in hematologic malignancies. Haematologica 86(12): 1261-1269

Bosshart, H. 2003: Interleukin-3 receptors in Hodgkin's disease. American Journal of Pathology 162(1): 355-6; author reply 356-7

Brizzi, M.F.; Formato, L.; Dentelli, P.; Rosso, A.; Pavan, M.; Garbarino, G.; Pegoraro, M.; Camussi, G.; Pegoraro, L. 2001: Interleukin-3 stimulates migration and proliferation of vascular smooth muscle cells: a potential role in atherogenesis. Circulation 103(4): 549-554

Wang, J.-M.; Lai, M.-Z.; Yang-Yen, H.-F. 2003: Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway. Molecular and Cellular Biology 23(6): 1896-1909

Bryder, D.; Jacobsen, S.E. 2000: Interleukin-3 supports expansion of long-term multilineage repopulating activity after multiple stem cell divisions in vitro. Blood 96(5): 1748-1755

Khaled, A.R.; Reynolds, D.A.; Young, H.A.; Thompson, C.B.; Muegge, K.; Durum, S.K. 2001: Interleukin-3 withdrawal induces an early increase in mitochondrial membrane potential unrelated to the Bcl-2 family. Roles of intracellular pH, ADP transport, and F(0)F(1)-ATPase. Journal of Biological Chemistry 276(9): 6453-6462

Zheng, X.; Karsan, A.; Duronio, V.; Chu, F.; Walker, D.C.; Bai, T.R.; Schellenberg, R.R. 2002: Interleukin-3, but not granulocyte-macrophage colony-stimulating factor and interleukin-5, inhibits apoptosis of human basophils through phosphatidylinositol 3-kinase: requirement of NF-kappaB-dependent and -independent pathways. Immunology 107(3): 306-315

Bentley, J.; Itchayanan, D.; Barnes, K.; McIntosh, E.; Tang, X.; Downes, C.P.; Holman, G.D.; Whetton, A.D.; Owen-Lynch, P.J.; Baldwin, S.A. 2003: Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface. Journal of Biological Chemistry 278(41): 39337-39348

Baumeister, T.; Rössner, S.; Pech, G.; de Bruijn, M.F.T.R.; Leenen, P.J.M.; Schuler, G.; Lutz, M.B. 2003: Interleukin-3Ralpha+ myeloid dendritic cells and mast cells develop simultaneously from different bone marrow precursors in cultures with interleukin-3. Journal of Investigative Dermatology 121(2): 280-288

Gabay, C.; Porter, B.; Guenette, D.; Billir, B.; Arend, W.P. 1999: Interleukin-4 (IL-4) and IL-13 enhance the effect of IL-1beta on production of IL-1 receptor antagonist by human primary hepatocytes and hepatoma HepG2 cells: differential effect on C-reactive protein production. Blood 93(4): 1299-1307

Denizot, Y.; Besse, A.; Raher, S.; Nachat, R.; Trimoreau, F.; Praloran, V.; Godard, A. 1999: Interleukin-4 (IL-4), but not IL-10, regulates the synthesis of IL-6, IL-8 and leukemia inhibitory factor by human bone marrow stromal cells. Biochimica et Biophysica Acta 1449(1): 83-92

Woods, J.M.; Tokuhira, M.; Berry, J.C.; Katschke, K.J.; Kurata, H.; Damergis, J.A.; Arai, K.; Koch, A.E. 1999: Interleukin-4 adenoviral gene therapy reduces production of inflammatory cytokines and prostaglandin E2 by rheumatoid arthritis synovium ex vivo. Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research 47(6): 285-292

Cook, H.T.; Singh, S.J.; Wembridge, D.E.; Smith, J.; Tam, F.W.; Pusey, C.D. 1999: Interleukin-4 ameliorates crescentic glomerulonephritis in Wistar Kyoto rats. Kidney International 55(4): 1319-1326

Winsor, G.L.; Waterhouse, C.C.; MacLellan, R.L.; Stadnyk, A.W. 2000: Interleukin-4 and IFN-gamma differentially stimulate macrophage chemoattractant protein-1 (MCP-1) and eotaxin production by intestinal epithelial cells. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 20(3): 299-308

Garber, T.R.; Gonias, S.L.; Webb, D.J. 2000: Interleukin-4 and IL-10 bind covalently to activated human alpha2-macroglobulin by a mechanism that requires Cys949. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 20(2): 125-131

Vecchiet, J.; Dalessandro, M.; Travasi, F.; Falasca, K.; Di Iorio, A.; Schiavone, C.; Zingariello, P.; Di Ilio, E.; Pizzigallo, E.; Paganelli, R. 2003: Interleukin-4 and interferon-gamma production during HIV-1 infection and changes induced by antiretroviral therapy. International Journal of Immunopathology and Pharmacology 16(2): 157-166

Velazquez, J.R.; Lacy, P.; Mahmudi-Azer, S.; Bablitz, B.; Milne, C.D.; Denburg, J.A.; Moqbel, R. 2000: Interleukin-4 and RANTES expression in maturing eosinophils derived from human cord blood CD34+ progenitors. Immunology 101(3): 419-425

Noguchi, K.; Shitashige, M.; Watanabe, H.; Murota, S.; Ishikawa, I. 1999: Interleukin-4 and interferon-gamma inhibit prostaglandin production by interleukin-1beta-stimulated human periodontal ligament fibroblasts. Inflammation 23(1): 1-13

Loman, S.; Jansen, H.M.; Out, T.A.; Lutter, R. 1999: Interleukin-4 and interferon-gamma synergistically increase secretory component gene expression, but are additive in stimulating secretory immunoglobulin A release by Calu-3 airway epithelial cells. Immunology 96(4): 537-543

Paludan, S.R. 1998: Interleukin-4 and interferon-gamma: the quintessence of a mutual antagonistic relationship. Scandinavian Journal of Immunology 48(5): 459-468

Sasaki, S.; Nishikawa, S.; Miura, T.; Mizuki, M.; Yamada, K.; Madarame, H.; Tagawa, Y.I.; Iwakura, Y.; Nakane, A. 2000: Interleukin-4 and interleukin-10 are involved in host resistance to Staphylococcus aureus infection through regulation of gamma interferon. Infection and Immunity 68(5): 2424-2430

Molina-Holgado, E.; Arévalo-Martín, A.; Castrillo, A.; Boscá, L.; Vela, Jé.M.; Guaza, C. 2002: Interleukin-4 and interleukin-10 modulate nuclear factor kappaB activity and nitric oxide synthase-2 expression in Theiler's virus-infected brain astrocytes. Journal of Neurochemistry 81(6): 1242-1252

Van Den Berg, J.G.; Aten, J.; Chand, M.A.; Claessen, N.; Dijkink, L.; Wijdenes, J.; Lakkis, F.G.; Weening, J.J. 2000: Interleukin-4 and interleukin-13 act on glomerular visceral epithelial cells. Journal of the American Society of Nephrology: Jasn 11(3): 413-422

Machino, T.; Hashimoto, S.; Gon, Y.; Kujime, K.; Maruoka, S.; Horie, T. 2001: Interleukin-4 and interleukin-13 induce fibronectin production by human lung fibroblasts. Allergology International 50(3): 197-202

Scopes, J.; Massey, H.M.; Ebrahim, H.; Horton, M.A.; Flanagan, A.M. 2001: Interleukin-4 and interleukin-13: Bidirectional effects on human osteoclast formation. Bone 29(3): 203-208

Parry, R.G.; Gillespie, K.M.; Parnham, A.; Clark, A.G.; Mathieson, P.W. 1999: Interleukin-4 and interleukin-4 receptor polymorphisms in minimal change nephropathy. Clinical Science 96(6): 665-668

Pampura, A.N.; Suyatkina, O.B.; Bobrovskaya, T.A.; Morozova, O.V.; Pogomy, N.N.; Cheburkin, A.A. 2001: Interleukin-4 and interleukin-5 determination in children with atopic dermatitis: Its role for evaluation of disease's severity. Course and prognosis. Pediatriya (Moscow) (2): 13-16

Seah, G.T.; Gao, P.S.; Hopkin, J.M.; Rook, G.A. 2001: Interleukin-4 and its alternatively spliced variant (IL-4delta2) in patients with atopic asthma. American Journal of Respiratory and Critical Care Medicine 164(6): 1016-1018

Blease, K.; Seybold, J.; Adcock, I.M.; Hellewell, P.G.; Burke-Gaffney, A. 1998: Interleukin-4 and lipopolysaccharide synergize to induce vascular cell adhesion molecule-1 expression in human lung microvascular endothelial cells. American Journal of Respiratory Cell and Molecular Biology 18(5): 620-630

Cornicelli, J.A.; Butteiger, D.; Rateri, D.L.; Welch, K.; Daugherty, A. 2000: Interleukin-4 augments acetylated LDL-induced cholesterol esterification in macrophages. Journal of Lipid Research 41(3): 376-383

Acosta Rodriguez, E.V.; Zuñiga, E.; Montes, C.L.; Gruppi, A. 2003: Interleukin-4 biases differentiation of B cells from Trypanosoma cruzi-infected mice and restrains their fratricide: role of Fas ligand down-regulation and MHC class II-transactivator up-regulation. Journal of Leukocyte Biology 73(1): 127-136

King, V.L.; Szilvassy, S.J.; Daugherty, A. 2002: Interleukin-4 deficiency decreases atherosclerotic lesion formation in a site-specific manner in female LDL receptor-/- mice. Arteriosclerosis Thrombosis and Vascular Biology 22(3): 456-461

Karachunski, P.I.; Ostlie, N.S.; Okita, D.K.; Conti-Fine, B.M. 1999: Interleukin-4 deficiency facilitates development of experimental myasthenia gravis and precludes its prevention by nasal administration of CD4+ epitope sequences of the acetylcholine receptor. Journal of Neuroimmunology 95(1-2): 73-84

Keelan, J.A.; Sato, T.A.; Hansen, W.R.; Gilmour, J.S.; Gupta, D.K.; Helsby, N.A.; Mitchell, M.D. 1999: Interleukin-4 differentially regulates prostaglandin production in amnion-derived WISH cells stimulated with pro-inflammatory cytokines and epidermal growth factor. Prostaglandins Leukotrienes and Essential Fatty Acids 60(4): 255-262

Aung, S.; Tang, Y.W.; Graham, B.S. 1999: Interleukin-4 diminishes CD8(+) respiratory syncytial virus-specific cytotoxic T-lymphocyte activity in vivo. Journal of Virology 73(11): 8944-8949

Kitaura, H.; Nagata, N.; Fujimura, Y.; Hotokezaka, H.; Tatamiya, M.; Nakao, N.; Yoshida, N.; Nakayama, K. 2003: Interleukin-4 directly inhibits tumor necrosis factor-alpha-mediated osteoclast formation in mouse bone marrow macrophages. Immunology Letters 88(3): 193-198

Manna, S.K.; Aggarwal, B.B. 1998: Interleukin-4 down-regulates both forms of tumor necrosis factor receptor and receptor-mediated apoptosis, NF-kappaB, AP-1, and c-Jun N-terminal kinase. Comparison with interleukin-13. Journal of Biological Chemistry 273(50): 33333-33341

Catani, L.; Amabile, M.; Luatti, S.; Valdrè, L.; Vianelli, N.; Martinelli, G.; Tura, S. 2001: Interleukin-4 downregulates nuclear factor-erythroid 2 (NF-E2) expression in primary megakaryocytes and in megakaryoblastic cell lines. Stem Cells 19(4): 339-347

Profita, M.; Vignola, A.M.; Sala, A.; Mirabella, A.; Siena, L.; Pace, E.; Folco, G.; Bonsignore, G. 1999: Interleukin-4 enhances 15-lipoxygenase activity and incorporation of 15(S)-HETE into cellular phospholipids in cultured pulmonary epithelial cells. American Journal of Respiratory Cell and Molecular Biology 20(1): 61-68

Faber, C.; Terao, E.; Morga, E.; Heuschling, P. 2000: Interleukin-4 enhances the in vitro precursor cell recruitment for tumor-specific T lymphocytes in patients with glioblastoma. Journal of ImmunoTherapy 23(1): 11-16

Li-Jiawen; Liu-Daofan; Cheng-Jiqun; Et-Al 2001: Interleukin-4 in experimental murine systemic candidiasis. Zhonghua Pifuke Zazhi 34(5): 343-345

Bischoff, S.C.; Sellge, G.; Manns, M.P.; Lorentz, A. 2001: Interleukin-4 induces a switch of human intestinal mast cells from proinflammatory cells to Th2-type cells. International Archives of Allergy and Immunology 124(1-3): 151-154

Yonemitsu, J. 2001: Interleukin-4 induces mouse cytomegalovirus interstitial pneumonia in a latent infection model. Kurume Medical Journal 48(1): 49-54

Trindade, M.C.; Nakashima, Y.; Lind, M.; Sun, D.H.; Goodman, S.B.; Maloney, W.J.; Schurman, D.J.; Smith, R.L. 1999: Interleukin-4 inhibits granulocyte-macrophage colony-stimulating factor, interleukin-6, and tumor necrosis factor-alpha expression by human monocytes in response to polymethylmethacrylate particle challenge in vitro. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society 17(6): 797-802

Taki, H.; Sugiyama, E.; Kuroda, A.; Mino, T.; Kobayashi, M. 2000: Interleukin-4 inhibits interleukin-11 production by rheumatoid synovial cells. Rheumatology 39(7): 728-731

Lee, I.Yong.; Kim, J.; Ko, E-Mi.; Jeoung, E.Jun.; Kwon, Y-Guen.; Choe, J. 2002: Interleukin-4 inhibits the vascular endothelial growth factor- and basic fibroblast growth factor-induced angiogenesis in vitro. Molecules and Cells 14(1): 115-121

Brodbeck, W.G.; Shive, M.S.; Colton, E.; Ziats, N.P.; Anderson, J.M. 2002: Interleukin-4 inhibits tumor necrosis factor-alpha-induced and spontaneous apoptosis of biomaterial-adherent macrophages. Journal of Laboratory and Clinical Medicine 139(2): 90-100

Zheng, K.C.; Ariizumi, M. 2002: Interleukin-4 interleukin-5 expression in mice exposed to 2, 4-toluene diisocyanate. Journal of Occupational Health 44(6): 421-426

Tanaka, H.; Kawada, N.; Yamada, T.; Kawada, K.; Nagai, H. 2000: Interleukin-4 is involved in allergen-induced airway eosinophilic inflammation and bronchial hyperresponsiveness independent of genetic background. Allergology International 49(4): 253-261

Kitajima, H.; Okubo, Y.; Honda, J.; Yonemitsu, J.; Yoshida, N.; Fumimori, T.; Oizumi, K. 2001: Interleukin-4 is needed for the infection of monocytes by human cytomegalovirus. Intervirology 44(4): 264-270

Deng, J.; Hua, K.; Lesser, S.S.; Greiner, A.H.; Walter, A.W.; Marrero, M.B.; Harp, J.B. 2000: Interleukin-4 mediates STAT6 activation in 3T3-L1 preadipocytes but not adipocytes. Biochemical and Biophysical Research Communications 267(2): 516-520

Chang, T.L.; Peng, X.; Fu, X.Y. 2000: Interleukin-4 mediates cell growth inhibition through activation of Stat1. Journal of Biological Chemistry 275(14): 10212-10217

Aumüller, E.; Gibbs, B.F.; Gronow, A.; Haas, H. 2003: Interleukin-4 production from human basophils is critically dependent on the storage conditions employed prior to stimulation. Inflammation Research: Official Journal of the European Histamine Research Society . 52(3): 107-110

Metwali, A.; Blum, A.; Elliott, D.E.; Weinstock, J.V. 2002: Interleukin-4 receptor alpha chain and STAT6 signaling inhibit gamma interferon but not Th2 cytokine expression within schistosome granulomas. Infection and Immunity 70(10): 5651-5658

Borish, L.C.; Nelson, H.S.; Lanz, M.J.; Claussen, L.; Whitmore, J.B.; Agosti, J.M.; Garrison, L. 1999: Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial. American Journal of Respiratory and Critical Care Medicine 160(6): 1816-1823

Husain, S.R.; Kawakami, K.; Kawakami, M.; Puri, R.K. 2003: Interleukin-4 receptor-targeted cytotoxin therapy of androgen-dependent and -independent prostate carcinoma in xenograft models. Molecular Cancer Therapeutics 2(3): 245-254

Rishikof, D.C.; Ricupero, D.A.; Kuang, P.-P.; Liu, H.; Goldstein, R.H. 2002: Interleukin-4 regulates connective tissue growth factor expression in human lung fibroblasts. Journal of Cellular Biochemistry 85(3): 496-504

Bonder, C.S.; Finlay-Jones, J.J.; Hart, P.H. 1999: Interleukin-4 regulation of human monocyte and macrophage interleukin-10 and interleukin-12 production. Role of a functional interleukin-2 receptor gamma-chain. Immunology 96(4): 529-536

Davies, J.D.; Mueller, R.; Minson, S.; O'Connor, E.; Krahl, T.; Sarvetnick, N. 1999: Interleukin-4 secretion by the allograft fails to affect the allograft-specific interleukin-4 response in vitro. Transplantation 67(12): 1583-1589

Levings, M.K.; Bessette, D.C.; Schrader, J.W. 1999: Interleukin-4 synergizes with Raf-1 to promote long-term proliferation and activation of c-jun N-terminal kinase. Blood 93(11): 3694-3702

Rüger, B.M.; Erb, K.J.; He, Y.; Lane, J.M.; Davis, P.F.; Hasan, Q. 2000: Interleukin-4 transgenic mice develop glomerulosclerosis independent of immunoglobulin deposition. European Journal of Immunology 30(9): 2698-2703

Messingham, K.A.N.; Heinrich, S.A.; Schilling, E.M.; Kovacs, E.J. 2002: Interleukin-4 treatment restores cellular immunity after ethanol exposure and burn injury. Alcoholism Clinical and Experimental Research 26(4): 519-526

Czarneski, J.; Meyers, J.; Peng, T.; Abraham, V.; Mick, R.; Ross, S.R. 2001: Interleukin-4 up-regulates mouse mammary tumor virus expression yet is not required for in vivo virus spread. Journal of Virology 75(23): 11886-11890

Srivannaboon, K.; Shanafelt, A.B.; Todisco, E.; Forte, C.P.; Behm, F.G.; Raimondi, S.C.; Pui, C.H.; Campana, D. 2001: Interleukin-4 variant (BAY 36-1677) selectively induces apoptosis in acute lymphoblastic leukemia cells. Blood 97(3): 752-758

Kawakami, K.; Hossain Qureshi, M.; Zhang, T.; Koguchi, Y.; Xie, Q.; Kurimoto, M.; Saito, A. 1999: Interleukin-4 weakens host resistance to pulmonary and disseminated cryptococcal infection caused by combined treatment with interferon-gamma-inducing cytokines. Cellular Immunology 197(1): 55-61

Khalil, H.M.; Abd el Baki, M.H.; Abd el Mawla, M.M.; Maklad, K.M.; Sharaf, S.A.; Saad, A.E. 1999: Interleukin-4, immunoglobulin E and immunoglobulin A and resistance to re-infection with Schistosoma haematobium before and after chemotherapy. Journal of the Egyptian Society of Parasitology 29(2): 395-408

Wirjatijasa, F.; Dehghani, F.; Blaheta, R.A.; Korf, H-Werner.; Hailer, N.P. 2002: Interleukin-4, interleukin-10, and interleukin-1-receptor antagonist but not transforming growth factor-beta induce ramification and reduce adhesion molecule expression of rat microglial cells. Journal of Neuroscience Research 68(5): 579-587

Wen, F-Qiang.; Kohyama, T.; Liu, X.; Zhu, Y.Kui.; Wang, H.; Kim, H.Jun.; Kobayashi, T.; Abe, S.; Spurzem, J.R.; Rennard, S.I. 2002: Interleukin-4- and interleukin-13-enhanced transforming growth factor-beta2 production in cultured human bronchial epithelial cells is attenuated by interferon-gamma. American Journal of Respiratory Cell and Molecular Biology 26(4): 484-490

Satoskar, A.R.; Elizondo, J.; Monteforte, G.M.; Stamm, L.M.; Bluethmann, H.; Katavolos, P.; Telford, S.R. 2000: Interleukin-4-deficient BALB/c mice develop an enhanced Th1-like response but control cardiac inflammation following Borrelia burgdorferi infection. FEMS Microbiology Letters 183(2): 319-325

Yahata, T.; Yahata, C.; Ohta, A.; Sekimoto, M.; Kitamura, H.; Iwakabe, K.; Habu, S.; Azuma, S.; Nakui, M.; Sato, M.; Koda, T.; Nishimura, T. 2000: Interleukin-4-dependent induction of preproenkephalin in antigen-specific T helper-type 2 (Th2) cells. Journal of Neuroimmunology 105(2): 103-108

Hayashi, T.; Yasutomi, Y.; Hasegawa, K.; Sasaki, Y.; Onodera, T. 2003: Interleukin-4-expressing plasmid DNA inhibits reovirus type-2-triggered autoimmune insulitis in DBA/1 J suckling mice. International Journal of Experimental Pathology 84(2): 101-106

Doseff, A.I.; Baker, J.H.; Bourgeois, T.A.; Wewers, M.D. 2003: Interleukin-4-induced apoptosis entails caspase activation and suppression of extracellular signal-regulated kinase phosphorylation. American Journal of Respiratory Cell and Molecular Biology 29(3 Part 1): 367-374

Pesu, M.; Takaluoma, K.; Aittomäki, S.; Lagerstedt, A.; Saksela, K.; Kovanen, P.E.; Silvennoinen, O. 2000: Interleukin-4-induced transcriptional activation by stat6 involves multiple serine/threonine kinase pathways and serine phosphorylation of stat6. Blood 95(2): 494-502

Kitamura, Y.; Taniguchi, T.; Kimura, H.; Nomura, Y.; Gebicke-Haerter, P.J. 2000: Interleukin-4-inhibited mRNA expression in mixed rat glial and in isolated microglial cultures. Journal of Neuroimmunology 106(1-2): 95-104

Paludan, S.R.; Ellermann-Eriksen, S.; Lovmand, J.; Mogensen, S.C. 1999: Interleukin-4-mediated inhibition of nitric oxide production in interferon-gamma-treated and virus-infected macrophages. Scandinavian Journal of Immunology 49(2): 169-176

Wurster, A.L.; Rodgers, V.L.; White, M.F.; Rothstein, T.L.; Grusby, M.J. 2002: Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL. Journal of Biological Chemistry 277(30): 27169-27175

Saarinen, J.V.; Harvima, R.J.; Naukkarinen, A.; Horsmanheimo, M.; Harvima, I.T. 2001: Interleukin-4-positive mast cells are highly associated with the extent of immediate allergic wheal reaction in the skin. Allergy 56(1): 58-64

Foster, P.S.; Hogan, S.P.; Yang, M.; Mattes, J.; Young, I.G.; Matthaei, K.I.; Kumar, R.K.; Mahalingam, S.; Webb, D.C. 2002: Interleukin-5 and eosinophils as therapeutic targets for asthma. Trends in Molecular Medicine 8(4): 162-167

Sanmugalingham, D.; De Vries, E.; Gauntlett, R.; Symon, F.A.; Bradding, P.; Wardlaw, A.J. 2000: Interleukin-5 enhances eosinophil adhesion to bronchial epithelial cells. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology 30(2): 255-263

Stirling, R.G.; van Rensen, E.L.; Barnes, P.J.; Chung, K.F. 2001: Interleukin-5 induces CD34(+) eosinophil progenitor mobilization and eosinophil CCR3 expression in asthma. American Journal of Respiratory and Critical Care Medicine 164(8 Part 1): 1403-1409

Dewson, G.; Cohen, G.M.; Wardlaw, A.J. 2001: Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils. Blood 98(7): 2239-2247

Bae, S.J.; Tanaka, Y.; Hakugawa, J.; Katayama, I. 1999: Interleukin-5 involvement in ovalbumin-induced eosinophil infiltration in mouse food-allergy model. Journal of Dermatological Science 21(1): 1-7

Umland, S.P.; Razac, S.; Shah, H.; Nahrebne, D.K.; Egan, R.W.; Billah, M.M. 1998: Interleukin-5 mRNA stability in human T cells is regulated differently than interleukin-2, interleukin-3, interleukin-4, granulocyte/macrophage colony-stimulating factor, and interferon-gamma. American Journal of Respiratory Cell and Molecular Biology 18(5): 631-642

Salvi, S.; Semper, A.; Blomberg, A.; Holloway, J.; Jaffar, Z.; Papi, A.; Teran, L.; Polosa, R.; Kelly, F.; Sandström, T.; Holgate, S.; Frew, A. 1999: Interleukin-5 production by human airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology 20(5): 984-991

Lio, D.; D'Anna, C.; Scola, L.; Di Lorenzo, G.; Colombo, A.; Listì, F.; Balistreri, C.R.; Candore, G.; Caruso, C. 1999: Interleukin-5 production by mononuclear cells from aged individuals: Implication for autoimmunity. Mechanisms of Ageing and Development 106(3): 297-304

Mishra, A.; Weaver, T.E.; Beck, D.C.; Rothenberg, M.E. 2001: Interleukin-5-mediated allergic airway inflammation inhibits the human surfactant protein C promoter in transgenic mice. Journal of Biological Chemistry 276(11): 8453-8459

Tomsic Matić, M.; Derganc, M.; Wraber, B.; Primozic, J. 2000: Interleukin-6 (IL-6) and soluble receptors for interleukin-2 (sIL-2R) in the diagnosis of early severe infection in the critically ill newborns. Pflugers Archiv: European Journal of Physiology 440(5 Suppl): R75-R77

Jones, K.G.; Brull, D.J.; Brown, L.C.; Sian, M.; Greenhalgh, R.M.; Humphries, S.E.; Powell, J.T. 2001: Interleukin-6 (IL-6) and the prognosis of abdominal aortic aneurysms. Circulation 103(18): 2260-2265