EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Iron status in pregnant women: which measurements are valid?



Iron status in pregnant women: which measurements are valid?



British Journal of Haematology 103(3): 817-824



Anaemia in pregnancy in developing countries continues to be a public health problem of significant proportion. At least 50% of the anaemia has been blamed on iron deficiency. In populations where chronic inflammation and iron deficiency anaemia coexist, the criteria to accurately define iron status are not always clear. Similarly, in pregnancy, with marked physiological changes, cut-off points for biochemical parameters need to be re-examined. In this study we examined the diagnostic accuracy of iron parameters including mean cellular volume (MCV), serum iron, transferrin, total iron binding capacity (TIBC) and its saturation, zinc protoporphyrin (ZPP), ferritin and serum transferrin receptor (TfR) for the assessment of iron status in a population of anaemic pregnant women in Malawi. Stained bone marrow aspirates were used as the standard for comparison. Results show that for the purpose of screening, serum ferritin is the best single indicator of storage iron provided a cut-off point of 30 microg/l is used. A number of other commonly used parameters of iron status were shown to have limited diagnostic accuracy. Logistic regression was used to obtain mathematical models for the prediction of bone marrow iron status using a combination of available parameters.

(PDF emailed within 0-6 h: $19.90)

Accession: 010885371

Download citation: RISBibTeXText

PMID: 9858238

DOI: 10.1046/j.1365-2141.1998.01035.x



Related references

Influence of prenatal iron and zinc supplements on supplemental iron absorption, red blood cell iron incorporation, and iron status in pregnant Peruvian women. American Journal of Clinical Nutrition 69(3): 509-515, 1999

Evaluation of iron status in chadian pregnant women consequences of maternal iron deficiency on the hematopoietic status of newborns. Tropical & Geographical Medicine 40(1): 1-6, 1988

Iron status in Ecuadorian pregnant women living at 2,800 m altitude: relationship with infant iron status. International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift für Vitamin- und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition 57(3): 327-332, 1987

Anemia and iron status of pregnant and non pregnant women in the guinea savanna of nigeria. Annals of Tropical Medicine & Parasitology 79(5): 485-494, 1985

Serum Ferritin is a Reliable, Non-invasive Test for Iron Status in Pregnancy: Comparison of Ferritin with Other Iron Status Markers in a Longitudinal Study on Healthy Pregnant Women; Erythropoiesis. Hematology 5(4): 319-325, 2001

Iron status of pregnant Indian women from an area of active iron supplementation. Nutrition 30(3): 291-296, 2014

Effect of iron supplementation on the iron status of pregnant women: consequences for newborns. American Journal of Clinical Nutrition 66(5): 1178-1182, 1997

The iron status and dietary iron intake of non supplemented pregnant women. Proceedings of the Nutrition Society 43(3): 99A, 1984

Iron status markers in nonanemic pregnant women with and without iron supplementation. International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics 100(2): 130-132, 2007

Assessment of iron deficiency in pregnant women by determining iron status. Journal of Ayub Medical College, Abbottabad 23(2): 36-40, 2014

Impact of prophylactic iron supplementation in healthy pregnant women on maternal iron status and birth outcome. Food and Nutrition Bulletin 32(3): 213-217, 2011

The effectiveness of weekly iron supplementation regimen in improving the iron status of Chinese children and pregnant women. Biomedical and Environmental Sciences 9(2-3): 341-347, 1996

Periconceptional iron supplementation does not reduce anemia or improve iron status among pregnant women in rural Bangladesh. American Journal of Clinical Nutrition 90(5): 1295-1302, 2010