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Irruption of genomics in the search for disease related genes



Irruption of genomics in the search for disease related genes



Gut 52 Suppl 2: Ii1-Ii5



Genomics was initiated when robotics made possible the characterisation of large numbers of DNA fragments and when ever improving computers with dedicated software were applied to the localisation in the genome of these sequences and to the analysis of their content. By enabling the generation and management of large amounts of DNA based sequences these tools have changed our perception of the genomes of living organisms. These data, as applied to humans, are contributing to the understanding of gene function, disease processes, and evolution of our species. Presently they are changing the research strategies for identifying genetic variations influencing disease susceptibility and response to treatment. These advances will have a profound impact in biomedicine.

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Accession: 010885883

Download citation: RISBibTeXText

PMID: 12651875

DOI: 10.1136/gut.52.suppl_2.ii1



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