EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Is Doppler tissue velocity during early left ventricular filling preload independent?



Is Doppler tissue velocity during early left ventricular filling preload independent?



Heart 87(4): 336-339



Background: Transmitral Doppler flow indices are used to evaluate diastolic function. Recently, velocities measured by Doppler tissue imaging have been used as an index of left ventricular relaxation. Objective: To determine whether Doppler tissue velocities are influenced by alterations in preload. Methods: Left ventricular preload was altered in 17 patients (all men, mean (SD) age, 49 (8) years) during echocardiographic measurements of left ventricular end diastolic volume, maximum left atrial area, peak early Doppler filling velocity, and left ventricular myocardial velocities during early filling. Preload altering manoeuvres included Trendelenberg (stage 1), reverse Trendelenberg (stage 2), and amyl nitrate (stage 3). Systolic blood pressure was measured at each stage. Results: In comparison with baseline, left ventricular end diastolic volume (p=0.001), left atrial area (p=0.003), peak early mitral Doppler filling velocity (p=0.01), and systolic blood pressures (p=0.001) were all changed by preload altering manoeuvres. Only left ventricular myocardial velocity during early filling remained unchanged by these manoeuvres. Conclusions: In contrast to standard transmitral Doppler filling indices, Doppler tissue early diastolic velocities are not significantly affected by physiological manoeuvres that alter preload. Thus Doppler tissue velocities during early left ventricular diastole may provide a better index of diastolic function in cardiac patients by providing a preload independent assessment of left ventricular filling.

(PDF emailed within 0-6 h: $19.90)

Accession: 010885982

Download citation: RISBibTeXText

PMID: 11907005

DOI: 10.1136/heart.87.4.336



Related references

Color M-mode Doppler flow propagation velocity is a relatively preload-independent index of left ventricular filling. Journal of the American Society of Echocardiography 12(2): 129-137, 1999

Valsalva unmasks preload independency of the diastolic mitral annular velocities by Doppler tissue imaging and the preload dependency of the left ventricular early filling flow propagation by colour Doppler M-mode in normal subjects. European Heart Journal 19(ABST SUPPL ): 438, 1998

Color Doppler M-Mode Velocity Propagation An Index of Early Left Ventricular Filling That Combined with Pulsed Doppler Peak E Velocity may Predict Left Atrial Pressure. Journal of the American College of Cardiology 0(SPEC ISSUE): 335A, 1995

Preload affects doppler determined early left ventricular filling by relief of pericardial restraint. European Heart Journal 10(ABSTR SUPPL): 282, 1989

Influence of alteration in preload on the pattern of left ventricular diastolic filling as assessed by Doppler tissue imaging. European Heart Journal 20(ABSTR SUPPL ): 292, 1999

Impact of left ventricular ejection fraction on estimation of left ventricular filling pressures using tissue Doppler and flow propagation velocity. American Journal of Cardiology 91(6): 780-784, 2003

Influence of left ventricular preload reduction by hemodialysis on the doppler derived left ventricular filling profile. American Journal of Noninvasive Cardiology 4(6): 345-351, 1990

Influence of preload reduction on continuous-wave Doppler estimate to left ventricular relaxation Comparison with left ventricular filling indexes. Circulation 92(8 SUPPL ): I396-I397, 1995

Comparative value of tissue Doppler imaging and m-mode color Doppler mitral flow propagation velocity for the evaluation of left ventricular filling pressure. Chest 128(4): 2544-2550, 2005

Utility of preload alteration in assessment of left ventricular filling pressure by Doppler echocardiography: A simultaneous catheterization and Doppler echocardiographic study. Journal of the American College of Cardiology 30(2): 459-467, 1997

Striking effect of left ventricular high filling pressure with mitral regurgitation on mitral annular velocity during early diastole. A study using colour M-mode tissue Doppler imaging. European Journal of Echocardiography 3(1): 52-58, 2002

Comparison between tissue Doppler imaging and velocity-encoded magnetic resonance imaging for measurement of myocardial velocities, assessment of left ventricular dyssynchrony, and estimation of left ventricular filling pressures in patients with ischemic cardiomyopathy. American Journal of Cardiology 102(10): 1366-1372, 2008

Comparison of tissue Doppler and propagation velocity to invasive measures for measuring left ventricular filling pressures. American Journal of Cardiology 95(8): 1017-1020, 2005

Assessment of the temporal relationship between left ventricular relaxation and filling during early diastole using pulsed Doppler echocardiography and tissue Doppler imaging. Japanese Circulation Journal 63(3): 209-215, 1999