Isolation of 9Z beta-carotene from Dunaliella bardawil and its stereoselective synthesis
Yamano, Y.; Yoshizawa, M.; Ito, M.
Journal of Nutritional Science and Vitaminology 45(1): 49-62
ISSN/ISBN: 0301-4800 PMID: 10360241 Accession: 010892487
An isolation of 9Z beta-carotene from Dunaliella bardawil was accomplished by low-pressure column chromatography with Ca(OH)2 column. Furthermore, it was stereoselectively synthesized by Wittig reaction between the C10-phosphonium salt 2 and 9Z beta-apo-8 -carotenal 1, which was prepared by Emmons-Horner reaction of 9Z beta-ionylidene-acetaldehyde 3 with phosphonates 6 and 7 or 8a and 9.