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Membrane rafts in immunoreceptor signaling: New doubts, new proofs?

Membrane rafts in immunoreceptor signaling: New doubts, new proofs?

Trends in Immunology 23(12): 562-564

Immunoreceptors are believed to initiate their signaling by association with membrane rafts rich in src-family kinases and other signaling molecules. Although a recent paper casts doubt over this concept, by exposing drawbacks of a commonly used procedure to disturb rafts by cholesterol extraction, several other recent papers give further support to the concept.

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Accession: 010972771

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PMID: 12464560

DOI: 10.1016/s1471-4906(02)02330-x

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