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Pain reactivity in former extremely low birth weight infants at corrected age 8 months compared with term born controls



Pain reactivity in former extremely low birth weight infants at corrected age 8 months compared with term born controls



Infant Behavior and Development 24(1): 41-55



The aim was to examine whether early and prolonged exposure to pain in preterm infants has long lasting biobehavioral consequences at 8 months corrected age. Facial and cardiac autonomic responses to blood collection in former extremely low birth weight (ELBW; ltoreq800g) infants were compared with term born infants. Overall, the pattern of behavioral and cardiac responses to the lance were similar between the groups, however the ELBW infants displayed significantly higher basal heart rate, qualitative differences in heart rate variability during finger lance and recovery, and faster behavioral and physiological recovery. Furthermore, among the ELBW infants, higher number of previous invasive procedures experienced since birth was associated with dampened facial and heart rate reactions to finger lance. Higher resting heart rate among the ELBW infants suggests a possible "resetting" of autonomic regulation.

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Accession: 011113112

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DOI: 10.1016/s0163-6383(01)00065-0


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