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Precision of a mammalian circadian clock


Precision of a mammalian circadian clock



Die Naturwissenschaften 86(7): 333-335



ISSN/ISBN: 0028-1042

PMID: 10451856

DOI: 10.1007/s001140050628

This paper reports study of day-to-day instability in the locomotor activity rhythm of the nocturnal field mouse Mus booduga. The free-running period () of this rhythm was estimated in constant darkness in n=347 adult male mice. The "onset" and "offset" of locomotor activity rhythm were used as phase markers of the circadian clock. The precision of the onset of locomotor activity was observed to be a non-linear function of , with maximal precision at close to 24h. The precision of the offset of locomotor activity was found to increase with increasing . These results suggest that the homeostasis of is tighter when is close to 24h.

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Accession: 011179895

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