Section 12
Chapter 11,186

Pregnancy following transfer of cryopreserved-thawed embryos that had been a result of fertilization of all in vitro matured metaphase or germinal stage oocytes. case report

Check, M.L.; Brittingham, D.; Check, J.H.; Choe, J.K.

Clinical and Experimental Obstetrics and Gynecology 28(2): 69-70


ISSN/ISBN: 0390-6663
PMID: 11491375
Accession: 011185281

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Purpose: To see if pregnancies can be achieved after performing intracytoplasmic sperm injection (ICSI) of in vitro matured metaphase I or germinal vesicle stage oocytes and then cryopreserving them at the 2 pronuclear stage. Methods: Transfer of frozen/thawed hatched day 3 embryos to two women. All embryos were a result of in vitro maturation of immature oocytes followed by ICSI. Results: Both women conceived. One has delivered and one has successfully completed the first trimester. Conclusion: These two cases represent only the second and third reported cases of pregnancies following frozen embryo transfer where the embryos resulted from fertilizing immature oocytes by ICSI.

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