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Preparation via coligand exchange and characterization of (99mTc-EDDA-HYNIC-D-Phe1,Tyr3)Octreotide (99mTc-EDDA/HYNIC-TOC)



Preparation via coligand exchange and characterization of (99mTc-EDDA-HYNIC-D-Phe1,Tyr3)Octreotide (99mTc-EDDA/HYNIC-TOC)



Journal of Labelled Compounds and Radiopharmaceuticals 46(4): 307-318



(99mTc-EDDA-HYNIC-D-Phe1,Tyr3)octreotide (99mTc-EDDA/HYNIC-TOC) is a promising new agent with the potential to replace (111In-DTPA-D-Phe1)- octreotide in somatostatin receptor scintigraphy. This hydrazinonicotinic acid derivatized somatostatin complex contains ethylenediamine N,N' diacetic acid (EDDA) as a coligand resulting in a high in vitro and in vivo stability.

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Accession: 011189477

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DOI: 10.1002/jlcr.672


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