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Role of gamma interferon in controlling murine chlamydial genital tract infection



Role of gamma interferon in controlling murine chlamydial genital tract infection



Infection and Immunity 67(10): 5518-5521



Earlier investigations have not shown an important role for gamma interferon (IFN-gamma) in the early clearance of chlamydial infection from the murine female genital tract. In a model using a human genital isolate of Chlamydia trachomatis in IFN-gamma and IFN-gamma receptor knockout mice, we were able to demonstrate a major role for IFN-gamma in mediating control of infection throughout the course of infection.

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Accession: 011311485

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PMID: 10496942


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